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ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. Additionally we are shipping ABCB5 Antibodies (67) and ABCB5 Kits (11) and many more products for this protein.
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similar pattern of mRNA expression of Pregnane X Receptor (PXR (show NR1I2 Proteins)), cytochrome P4503A and MDR1 genes found in fish treated with different PXR (show NR1I2 Proteins) inducers suggests that the intrinsic association between these three genes is conserved in zebrafish
ABCB5 has a role in chemoresistance in Merkel Cell Carcinoma
Results suggest that ATP binding cassette subfamily B member 5 ABCB5/Abcb5 upregulates cellular glutathione levels to protect cells from various poisons.
ATP-binding cassette member B5 (ABCB5) identifies dermal immunoregulatory cells capable of exerting therapeutic immunoregulatory functions through engagement of programmed cell death 1 (show PDCD1 Proteins).
This is the first study showing the relationship between miR (show MLXIP Proteins)-340-5p and expression of ABCB5 in melanoma cells
c-MYC (show MYC Proteins) confers resistance to 5-fluorouracil through regulating ABCB5 expression in human colon cancer cells.
ABCB5 alleles alter susceptibility to haloperidol-induced toxicity (HIT) in mouse and humans.
The resistance of CD133(+) melanoma subpopulation is attributed to the enhanced drug efflux mediated by ATP-binding cassette sub-family B member 5 (ABCB5), since the knockdown of ABCB5 was found to sensitize CD133(+) cells to CAPE.
In melanoma-initiating cells, ABCB5 controls IL1beta (show IL1B Proteins) secretion, which serves to maintain slow cycling, chemoresistant cells through an IL1beta (show IL1B Proteins)/IL8 (show IL8 Proteins)/CXCR1 (show CXCR1 Proteins) cytokine signaling circuit.
Suggest that the helicase HAGE (show DDX43 Proteins) has a key role in the resistance of ABCB5+ malignant melanoma stem cells to IFNalpha treatment by promoting SOCS1 (show SOCS1 Proteins) expression.
ABCB5 and MDR1 gene expression correlate with drug resistance in acute leukemia patients.
ATP-binding cassette, sub-family B, member 5 (ABCB5) marks limbal stem cells (LSCs) and is required for LSC (show ARHGEF1 Proteins) maintenance, corneal development and repair
the helicase HAGE is required for ABCB5+ MMIC-dependent tumor growth through promoting RAS protein expression
Expression of Abcb5.ts (testis-specific (show AIF1 Proteins)) (AY766239), a transporter consisting of 1255 amino acids and comprising two transmembrane and nucleotide binding domains, is restricted to testis tissue. In contrast, Abcb5.e (AY766238) is ubiquitously expressed.
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005
ATP-binding cassette, sub-family B (MDR/TAP), member 5
, ATP-binding cassette, sub-family B, member 5
, ABC efflux transporter 5
, ATP-binding cassette sub-family B member 5
, ABCB5 P-gp
, ATP-binding cassette protein
, P-glycoprotein ABCB5