ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) ELISA Kits

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies (280) and ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Proteins (7) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 ELISA Kits at antibodies-online.com

Showing 4 out of 21 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Rat 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Human 0.076 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$779.90
Details
Mouse 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$779.90
Details
Rat
0.312 ng/mL - 20 ng/mL   96 Tests Log in to see 8 to 12 Days
$790.25
Details

More ELISA Kits for ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (show ABCB4 ELISA Kits), Bcrp (show ABCG2 ELISA Kits) and Mrp1 (show ABCC1 ELISA Kits) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. we review the emerging role of molecular dynamics simulation techniques in our understanding of the membrane-embedded conformation of P-gp (show ABCB4 ELISA Kits)--{REVIEW}

  2. Studied ABCB1 protein expression immunohistochemically in twelve human post-mortem brain regions known to play a role in schizophrenia, in 13 patients with schizophrenia and nine controls; found a significantly reduced density of ABCB1-expressing neurons in the left habenula.

  3. Using an integrated pathway-based approach, we identified polymorphisms in ABCC6 (show ABCC6 ELISA Kits), ABCB1 and CYP2C8 (show CYP2C8 ELISA Kits) associated with overall survival. These associations were replicated in a large independent cohort, highlighting the importance of pharmacokinetic genes as prognostic markers in Ewing sarcoma

  4. The authors found that transient TUBB3 (show TUBB3 ELISA Kits) activation, through ABCB1, in response to the stimulation of FOXO3a (show FOXO3 ELISA Kits) expression, significantly contributes to the cross-resistance of the paclitaxel-resistant cell population and consequently limits the efficacy of both agents where cancer cells have developed multiple resistance.

  5. MDR1 and CYP3A5 (show CYP3A5 ELISA Kits) genetic polymorphisms significantly influence plasma trough levels and therapeutic response of imatinib in patients with chronic myeloid leukemia (show BCL11A ELISA Kits). Patients with GG genotype for CYP3A5 (show CYP3A5 ELISA Kits)-A6986G (P=0.016) and TT genotype for MDR1-C3435T (P=0.013) polymorphisms had significantly higher trough levels of imatinib.

  6. Rescue experiments confirmed the combined role of LUCAT1, miR (show MLXIP ELISA Kits)-200c and ABCB1 on osteosarcoma proliferation, invasion and methotrexate resistance. Overall, results indicate the vital role of LUCAT1 in the methotrexate resistance regulation through miR (show MLXIP ELISA Kits)-200c/ABCB1 pathway, providing a novel insight and treatment strategy for osteosarcoma drug resistance.

  7. Mdr1 enforces T Cell homeostasis in the presence of intestinal bile acids.

  8. Data show that co-treated with vincristine and XL019, a inhibitor of JAK2 and P-glycoprotein (P-gp), up-regulated expression of p21 and phosphorylated H2A histone family, member X (pH2AX).

  9. Tangeretin could sensitize ABCB1-overexpressing cancer cells to chemotherapeutical agents by directly inhibiting ABCB1 transporter function.

  10. over-functional P-gp (show ABCB4 ELISA Kits) might play an important role in the pathogenesis of ITP (show ITPA ELISA Kits) and induce GCs (show GCLC ELISA Kits) resistance in nonresponsive ITP (show ITPA ELISA Kits) patients. The blockage of P-gp (show ABCB4 ELISA Kits) could be a promising therapeutic approach for GCs (show GCLC ELISA Kits)-resistant patients with ITP (show ITPA ELISA Kits).

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. conclusion, MDR1 (show ABCB4 ELISA Kits) and BCRP (show ABCG2 ELISA Kits) are expressed on apical membranes of the rodent placental SynT (show STX1A ELISA Kits)-II layer.

  2. Mdr1 (show ABCB4 ELISA Kits) enforces T Cell homeostasis in the presence of intestinal bile acids.

  3. Loss of ABCB1 expression is associated with neonatal hyperbilirubinemia.

  4. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (show ABCB4 ELISA Kits) ATPase (show DNAH8 ELISA Kits) activity

  5. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  6. Chrysosplenetin inhibited P-gp (show ABCB4 ELISA Kits) activity and reverse the up-regulated P-gp (show ABCB4 ELISA Kits) and MDR1 (show ABCB4 ELISA Kits) levels induced by artemisinin.

  7. Tamsulosin and tolterodine with P-gp (show ABCB4 ELISA Kits) gene expression and activity in an enantiomer-specific way.

  8. Pgp (show ABCB4 ELISA Kits)-coupled ATPase (show DNAH8 ELISA Kits) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  9. Data show that human transgenic mutant huntingtin (show HTT ELISA Kits) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (show ABCB4 ELISA Kits)) which suggests that MDR1 (show ABCB4 ELISA Kits) might be a potential therapeutic target for Huntington's disease.

  10. In vitro and in vivo downregulation of the ATP binding cassette transporter (show ABCC3 ELISA Kits) B1 by the HMG-CoA reductase (show HMGCR ELISA Kits) inhibitor simvastatin

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen Profile

Antigen Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP binding cassette subfamily B member 1 (ABCB1) antibody
  • ATP binding cassette subfamily B member 1 L homeolog (abcb1.L) antibody
  • ATP binding cassette subfamily B member 1A (Abcb1a) antibody
  • ATP binding cassette subfamily B member 1 (Abcb1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • malic enzyme complex, mitochondrial (Mod2) antibody
  • ABC20 antibody
  • ABCB1 antibody
  • Cd243 antibody
  • CLCS antibody
  • GP170 antibody
  • Mdr antibody
  • Mdr-1 antibody
  • Mdr1 antibody
  • Mdr1a antibody
  • Mdr1b antibody
  • Mod-2 antibody
  • Mod-2r antibody
  • Mod-2s antibody
  • Mod2-r antibody
  • Mod2-s antibody
  • p-gp antibody
  • PGP1 antibody
  • Pgy-1 antibody
  • Pgy1 antibody
  • xemdr antibody

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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