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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) Antibodies

The protein encoded by ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 Kits (22) and ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCC1 4363 P33527
ABCC1 17250 O35379
ABCC1 24565 Q8CG09
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Top anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 48 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, WB Western blot analysis of ABCC1 antibody (C-term) (ABIN390525) in Ramos... Flow cytometric analysis of NCI-H292 cells using ABCC1 Antibody (C-ter... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rat Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rat Un-conjugated FACS, IHC (fro), IHC (p), WB 1 mL Log in to see 11 to 16 Days
$832.33
Details
Human Mouse Un-conjugated FACS, IHC (fro), IHC (p), WB 1 mL Log in to see 11 to 16 Days
$832.33
Details
Human Goat Un-conjugated ELISA, WB EB08734 (0.05µg/ml) staining of A549 lysate (35µg protein in RIPA buff... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-MRP1 antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2... Anti-MRP1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details

ABCC1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
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Top referenced anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 Antibodies

  1. Human Monoclonal ABCC1 Primary Antibody for IHC (fro), IF - ABIN1105162 : Mendelson: Inaugural editorial in Clinical cancer research : an official journal of the American Association for Cancer Research 1999 (PubMed)
    Show all 6 references for ABIN1105162

  2. Human Monoclonal ABCC1 Primary Antibody for IHC (fro), IF - ABIN1105160 : Scheffer, Pijnenborg, Smit, Müller, Postma, Timens, van der Valk, de Vries, Scheper: Multidrug resistance related molecules in human and murine lung. in Journal of clinical pathology 2002 (PubMed)
    Show all 6 references for ABIN1105160

  3. Human Monoclonal ABCC1 Primary Antibody for IHC (fro), IF - ABIN1105161 : Flens, Izquierdo, Scheffer, Fritz, Meijer, Scheper, Zaman: Immunochemical detection of the multidrug resistance-associated protein MRP in human multidrug-resistant tumor cells by monoclonal antibodies. in Cancer research 1994 (PubMed)
    Show all 6 references for ABIN1105161

  4. Human Monoclonal ABCC1 Primary Antibody for FACS, IHC (fro) - ABIN187339 : Robey, Obrzut, Shukla, Polgar, Macalou, Bahr, Di Pietro, Ambudkar, Bates: Becatecarin (rebeccamycin analog, NSC 655649) is a transport substrate and induces expression of the ATP-binding cassette transporter, ABCG2, in lung carcinoma cells. in Cancer chemotherapy and pharmacology 2009 (PubMed)
    Show all 4 references for ABIN187339

  5. Human Monoclonal ABCC1 Primary Antibody for FACS, IHC (fro) - ABIN187338 : Wilson, Fraga, Rodriguez-Galindo, Hagedorn, Leggas, Stewart: Expression of the multi-drug resistance proteins and the pregnane X receptor in treated and untreated retinoblastoma. in Current eye research 2009 (PubMed)
    Show all 4 references for ABIN187338

  6. Chicken Polyclonal ABCC1 Primary Antibody for WB - ABIN2781507 : Nabekura, Yamaki, Ueno, Kitagawa: Effects of plant sterols on human multidrug transporters ABCB1 and ABCC1. in Biochemical and biophysical research communications 2008 (PubMed)

  7. Human Polyclonal ABCC1 Primary Antibody for EIA, WB - ABIN452701 : Siedlinski, Boezen, Boer, Smit, Postma: ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts. in Pharmacogenetics and genomics 2009 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. The scanning study identified 46 polymorphic variants by screening 30 exons of the ABCC1 gene with adjacent intronic fragments in 190 unrelated Polish individuals. A large fraction of variants represented rare or even completely novel ones.

  2. ILK (show ILK Antibodies) may have an important role in the progression of NSCLC, possibly through up-regulation of Snail (show SNAI1 Antibodies) and MRP1 (show MDM4 Antibodies).

  3. MRP1 (show MDM4 Antibodies) knockdown down-regulates the deposition of collagen and leads to a reduced hypertrophic scar fibrosis

  4. MRP1 (show MDM4 Antibodies) activity showed no significant change I primary colorectal cancer patients.

  5. Chronic arsenic exposure negatively correlates with the expression of MRP1 (show MDM4 Antibodies) in bronchoalveolar lavage cells in patients with lung cancer.

  6. The present study investigated the time course and dose dependency of the induction of three efflux proteins, P-gp (show ABCB4 Antibodies), MRP1 (show MDM4 Antibodies) and MRP5 (show ABCC5 Antibodies), in response to gemcitabine exposure in Capan-2 pancreatic cancer cell line at transcriptional and translational levels.

  7. Our data suggested that miR-7 (show LILRB1 Antibodies) mediated small cell lung cancer chemoresistance by repressing MRP1/ABCC1

  8. study shows that genetic variability in the nucleotide binding domain 1 has a significant impact on the ABCC1 transcript level in the target tissue and may modify survival of breast cancer patients

  9. The level of FBW7 expression in CNE2 cells was correlated with CDDP chemosensitivity. siRNA-mediated upregulation of FBW7 expression downregulated the expression of MRP, significantly increasing drug sensitivity in CNE2 cells.

  10. Single nucleotide polymorphisms in ABCC1 gene is associated with acute graft-versus-host disease.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. Lentivirus-based RNAi stably knocks down the expression of the Mrp1 gene in the established TM4 (show TPM4 Antibodies) sertoli cell line.

  2. neprilysin (show MME Antibodies) x ABCC1 double-deficient mice present a new model for early effects of amyloid-beta-related mild cognitive impairment that allows investigations without artificial overexpression of inherited Alzheimer's disease genes

  3. Expression of apoA-I (show APOA1 Antibodies) or ABCA1 (show ABCA1 Antibodies) can reduce steatosis by decreasing lipid storage in hepatocytes through lipid transport and may also reduce endoplasmic reticulum stress, further lessening hepatic steatosis

  4. Loss of Mrp1 coupled with reductions in steroid hormone levels leads to alterations in extrahepatic phase I, phase II and phase III metabolizing enzymes in a tissue-specific manner.

  5. Cd or H(2)O(2) exposure increased the expression of key transport genes, Mrp1 and Mrp2 (show ABCC2 Antibodies), in WT cells but not in metallothionein (show MT Antibodies)-null cells.

  6. These results identify Mrp1 as the transporter essential for S1P (show S1PR1 Antibodies) efflux from the endothelial cells and thus for inside-out S1P (show S1PR1 Antibodies) signaling to P-glycoprotein at the blood-brain and blood-spinal cord barriers.

  7. investigated changes in the expression and activity of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in highly purified lung dendritic cells during aging

  8. Data suggest glutathione offers neuroprotection against methylmercury toxicity in a manner dependent on MRP1-mediated efflux.

  9. Results show that the presence of Mdr1a (show ABCB4 Antibodies), Mdr1b (P-glycoprotein Pgp (show ABCB4 Antibodies)) and multidrug resistance-associated protein (show ABCC3 Antibodies) (MRP1) encoding genes in the olfactory mucosa of rat and mouse was confirmed by RT-PCR.

  10. Assessment of activity, exploratory behavior, and anxiety levels revealed behavioral alterations in Abcb1 (show ABCB1 Antibodies)(0/0) and Abcc1 (0/0) mice, whereas Abcg2 (show ABCG2 Antibodies)(0/0) mice were mostly unaffected.

Cow (Bovine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. P-gp (show ABCB4 Antibodies), Bcrp (show ABCG2 Antibodies) and Mrp1 are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.

Gene names and symbols associated with ABCC1

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (ABCC1) antibody
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1) antibody
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 1 (Abcc1) antibody
  • ABC29 antibody
  • ABCC antibody
  • Abcc1a antibody
  • Abcc1b antibody
  • Avcc1a antibody
  • GS-X antibody
  • Mdrap antibody
  • Mrp antibody
  • Mrp1 antibody

Protein level used designations for ABCC1

ATP-binding cassette transporter variant ABCC1delta-ex13 , ATP-binding cassette transporter variant ABCC1delta-ex13&14 , ATP-binding cassette transporter variant ABCC1delta-ex25 , ATP-binding cassette transporter variant ABCC1delta-ex25&26 , LTC4 transporter , leukotriene C(4) transporter , multidrug resistance-associated protein 1 , ATP-binding cassette, sub-family C (CFTR/MRP), member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1b , multiple drug resistance-associated protein , ATP-binding cassette sub-family C member 1 , multidrug resistance protein 1 , ATP-binding cassette sub-family C ( CFTR/MRP) member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1

GENE ID SPECIES
4363 Homo sapiens
17250 Mus musculus
403453 Canis lupus familiaris
281588 Bos taurus
395416 Gallus gallus
733619 Sus scrofa
100734674 Cavia porcellus
24565 Rattus norvegicus
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