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The protein encoded by ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCC11 Kits (10) and ABCC11 Proteins (6) and many more products for this protein.
Showing 10 out of 73 products:
Human Monoclonal ABCC11 Primary Antibody for IHC (fro), IF - ABIN1105164
Kruh, Guo, Hopper-Borge, Belinsky, Chen: ABCC10, ABCC11, and ABCC12. in Pflügers Archiv : European journal of physiology 2007
Show all 5 references for ABIN1105164
Human Polyclonal ABCC11 Primary Antibody for IHC (p), WB - ABIN650984
Sato, Amano, Ono, Ishida, Kodera, Matsumura, Yoneda, Masuda: Allele frequencies of the ABCC11 gene for earwax phenotypes among ancient populations of Hokkaido, Japan. in Journal of human genetics 2009
Human Monoclonal ABCC11 Primary Antibody for IF, ELISA - ABIN529878
Fuchs, Daniel, Sadeghi, Opelz, Naujokat: Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells. in Biochemical and biophysical research communications 2010
Cow (Bovine) Polyclonal ABCC11 Primary Antibody for EIA, WB - ABIN375006
Bortfeld, Rius, König, Herold-Mende, Nies, Keppler: Human multidrug resistance protein 8 (MRP8/ABCC11), an apical efflux pump for steroid sulfates, is an axonal protein of the CNS and peripheral nervous system. in Neuroscience 2006
MRP8 (show S100A8 Antibodies) elevated serum levels in patients with Behcet's disease indicate MRP8 (show S100A8 Antibodies) role in the pathogenetic mechanisms of Behcet's disease.
The ABCC11 gene SNP of the 538 G>A allele was associated with a downregulation of the mRNA expression of ApoD (show APOD Antibodies) in the apocrine glands, which may indicate a role for the ABCC11 gene in the mediation of osmidrosis
study revealed a novel role of MRP8 (show S100A8 Antibodies)/14 in the autophagy-mediated elimination of intracellular BCG (show SLC11A1 Antibodies) by promoting reactive oxygen species generation
Circulating MRP-8 (show S100A8 Antibodies)/14 is associated with TX-dependent platelet activation in ACS (show PLA2G15 Antibodies), even during low-dose aspirin treatment, suggesting a contribution of residual TX to MRP-8 (show S100A8 Antibodies)/14 shedding, which may further amplify platelet activation.
Data suggest that tissue infiltrating macrophages secreting MRP8 (show S100A8 Antibodies)/14 may contribute to myositis, by driving the local production of cytokines directly from muscle.
MRP8 (show S100A8 Antibodies)/14 can activate cells by binding to TLR4 (show TLR4 Antibodies), leading to the release of proinflammatory cytokines. These mediators can lead to increased disease activity in enthesitis-related arthritis.
Our results suggest that a specific type of toxicity, leukopenia, is associated with a particular variant of ABCC11, which is different from the earwax and eQTL (show EQTN Antibodies) variants.
High baseline serum MRP8 (show S100A8 Antibodies)/14 levels are associated with lower survival in Chinese peritoneal dialysis patients.
MRP8 (show S100A8 Antibodies) has a crucial role in stimulating IL-6 (show IL6 Antibodies) expression by rheumatoid arthritis fibroblast-like synoviocytes.
High expression of ATP-binding cassette transporter (show ABCA4 Antibodies) ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.
ATP-binding cassette protein C11
, ATP-binding cassette sub-family C member 11
, ATP-binding cassette transporter MRP8
, ATP-binding cassette transporter sub-family C member 11
, multi-resistance protein 8
, multidrug resistance-associated protein 8