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ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 Proteins (ABCC11)

The protein encoded by ABCC11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCC11 Antibodies (51) and ABCC11 Kits (10) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ABCC11 85320 Q96J66
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Top ABCC11 Proteins at

Showing 3 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 0.5 mg Log in to see 69 to 74 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days

ABCC11 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11) Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 11 (ABCC11) interaction partners

  1. MRP8 (show S100A8 Proteins) elevated serum levels in patients with Behcet's disease indicate MRP8 (show S100A8 Proteins) role in the pathogenetic mechanisms of Behcet's disease.

  2. The ABCC11 gene SNP of the 538 G>A allele was associated with a downregulation of the mRNA expression of ApoD (show APOD Proteins) in the apocrine glands, which may indicate a role for the ABCC11 gene in the mediation of osmidrosis

  3. study revealed a novel role of MRP8 (show S100A8 Proteins)/14 in the autophagy-mediated elimination of intracellular BCG (show SLC11A1 Proteins) by promoting reactive oxygen species generation

  4. Circulating MRP-8 (show S100A8 Proteins)/14 is associated with TX-dependent platelet activation in ACS (show PLA2G15 Proteins), even during low-dose aspirin treatment, suggesting a contribution of residual TX to MRP-8 (show S100A8 Proteins)/14 shedding, which may further amplify platelet activation.

  5. Data suggest that tissue infiltrating macrophages secreting MRP8 (show S100A8 Proteins)/14 may contribute to myositis, by driving the local production of cytokines directly from muscle.

  6. MRP8 (show S100A8 Proteins)/14 can activate cells by binding to TLR4 (show TLR4 Proteins), leading to the release of proinflammatory cytokines. These mediators can lead to increased disease activity in enthesitis-related arthritis.

  7. Our results suggest that a specific type of toxicity, leukopenia, is associated with a particular variant of ABCC11, which is different from the earwax and eQTL (show EQTN Proteins) variants.

  8. High baseline serum MRP8 (show S100A8 Proteins)/14 levels are associated with lower survival in Chinese peritoneal dialysis patients.

  9. MRP8 (show S100A8 Proteins) has a crucial role in stimulating IL-6 (show IL6 Proteins) expression by rheumatoid arthritis fibroblast-like synoviocytes.

  10. High expression of ATP-binding cassette transporter ABCC11 in breast tumors is associated with aggressive subtypes and low disease-free survival.

ABCC11 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This ABC full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. The product of this gene participates in physiological processes involving bile acids, conjugated steroids, and cyclic nucleotides. In addition, a SNP in this gene is responsible for determination of human earwax type. This gene and family member ABCC12 are determined to be derived by duplication and are both localized to chromosome 16q12.1. Multiple alternatively spliced transcript variants have been described for this gene.

Gene names and symbols associated with ABCC11

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 11 (ABCC11)
  • EWWD protein
  • MRP8 protein
  • WW protein

Protein level used designations for ABCC11

ATP-binding cassette protein C11 , ATP-binding cassette sub-family C member 11 , ATP-binding cassette transporter MRP8 , ATP-binding cassette transporter sub-family C member 11 , multi-resistance protein 8 , multidrug resistance-associated protein 8

85320 Homo sapiens
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