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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) Antibodies

The protein encoded by ABCC2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Proteins (9) and ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCC2 1244 Q92887
ABCC2 12780 Q8VI47
ABCC2 25303 Q63120
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Top anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Antibodies at antibodies-online.com

Showing 10 out of 56 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated IHC (fro), IF, WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated IHC (fro), IF, WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ABCC2 is approximately 0.03 ng/mL as a capture antibody. 0.05 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (fro), WB   500 μL Log in to see 11 to 16 Days
$536.07
Details
Human Mouse Un-conjugated FACS, IHC (fro), IHC (p), WB   1 mL Log in to see 11 to 16 Days
$832.33
Details
Mouse Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$419.83
Details

ABCC2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
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Mouse (Murine) ,
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Rat (Rattus)


Top referenced anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Antibodies

  1. Human Monoclonal ABCC2 Primary Antibody for ELISA, WB - ABIN394929 : Takahashi, Miura, Scott, Kagaya, Kameoka, Tagawa, Saitoh, Fujishima, Yoshioka, Hirokawa, Sawada: Influence of CYP3A5 and drug transporter polymorphisms on imatinib trough concentration and clinical response among patients with chronic phase chronic myeloid leukemia. in Journal of human genetics 2010 (PubMed)
    Show all 5 references for ABIN394929

  2. Mouse (Murine) Polyclonal ABCC2 Primary Antibody for WB - ABIN610784 : Cockcroft, Thomas, Fensome, Geny, Cunningham, Gout, Hiles, Totty, Truong, Hsuan: Phospholipase D: a downstream effector of ARF in granulocytes. in Science (New York, N.Y.) 1994 (PubMed)
    Show all 5 references for ABIN610784

  3. Human Monoclonal ABCC2 Primary Antibody for IHC (fro), IF - ABIN1105169 : Peng, Yanagida, Chen, Han: Ellipsoidal TiO2 hierarchitectures with enhanced photovoltaic performance. in Chemistry (Weinheim an der Bergstrasse, Germany) 2012 (PubMed)
    Show all 4 references for ABIN1105169

  4. Human Monoclonal ABCC2 Primary Antibody for IHC (fro), IF - ABIN1105167 : Paulusma, Bosma, Zaman, Bakker, Otter, Scheffer, Scheper, Borst, Oude Elferink: Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene. in Science (New York, N.Y.) 1996 (PubMed)
    Show all 4 references for ABIN1105167

  5. Human Monoclonal ABCC2 Primary Antibody for IHC (fro), IF - ABIN1105168 : Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997 (PubMed)
    Show all 2 references for ABIN1105168

More Antibodies against ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) interaction partners

  1. Resveratrol-3-O-sulfate reduced in both MRP2-overexpressing MDCKII-UGT1A1 (show UGT1A1 Antibodies) cells and Human UGT1A9 (show UGT1A9 Antibodies)-overexpressing HeLa cells.

  2. A thalassemia patient has been found to be a carrier of UGT1A1 (show UGT1A1 Antibodies) and ABCC2 polymorphisms explaining a possible reduction of desferasirox metabolism together with a reduction of biliary elimination by MRP2 and causing a serious adverse reaction.

  3. ABCC2 expression in PBMCs may be, in part, influenced by gender, and that at least two endogenous control genes should be utilized.

  4. Activation of liver PKCs during cholestasis leads to Ezrin (show EZR Antibodies) Thr567 phosphorylation resulting in MRP2 internalization and degradation where ubiquitin ligase E3 GP78 (show AMFR Antibodies) is involved.

  5. These studies identify Akt2 (show AKT2 Antibodies) as a critical kinase that regulates radixin (show RDX Antibodies) phosphorylation and leads to Mrp-2 translocation and function.

  6. MRP2 expression in HepG2 cells is repressed by IL-18 (show IL18 Antibodies).

  7. MRP 2 expression is upregulated by ATP in colorectal cancer cells and enhances their survival to chemotherapeutic drugs.

  8. There was no association of ABCC2 with risk of colorectal cancer.

  9. CYP3A4 (show CYP3A4 Antibodies)*22 and ABCC2 haplotypes did not influence tacrolimus trough concentrations

  10. ErbB2 (show ERBB2 Antibodies) modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein (show ABCC3 Antibodies) MRP-2.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) interaction partners

  1. Deficiency in Mrp2 lowers platinum excretion and increases susceptibility to kidney injury, which can be rescued by the human MRP2 ortholog.

  2. In Bcrp1;Mrp2;Mrp3(-/-), but not Bcrp1;Mdr1a/b;Mrp(-/-) mice.

  3. Cd or H(2)O(2) exposure increased the expression of key transport genes, Mrp1 (show ABCC1 Antibodies) and Mrp2, in WT cells but not in metallothionein (show MT Antibodies)-null cells.

  4. hepatic transporters Ntcp (show SLC10A1 Antibodies) and Mrp2 are downregulated in rodent models of necrotizing enterocolitis

  5. Both Abcc2 and Abcc3 (show ABCC3 Antibodies) significantly influenced the PK properties of MTX (show MTX1 Antibodies).

  6. hyperosmotic cholestasis is triggered by a NADPH oxidase (show NOX1 Antibodies)-driven reactive oxygen species formation that mediates Fyn (show FYN Antibodies)-dependent retrieval of the Mrp2 and Bsep (show ABCB11 Antibodies) from the canalicular membrane, which may involve an increased cortactin (show CTTN Antibodies) phosphorylation.

  7. Strain- and sex-dependent circadian patterns in abcc2 expressions displayed robust relations with the chronotolerance of ileum mucosa for irinotecan

  8. In ABCC2-deficient mice impaired ABCC2 function is associated with a significant increase in erythromycin metabolism.

  9. Membrane vesicles prepared from human erythrocytes, which express the MRP2 have important implications for the Selenium-dependent and -independent disposition of Arasenic.

  10. NHERF-1 (show SLC9A3R1 Antibodies) binds to Mrp2, and plays a critical role in the canalicular expression of Mrp2 and its function as a determinant of glutathione-dependent, bile acid-independent bile flow

ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 2 (ABCC2) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine\; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.

Gene names and symbols associated with ABCC2

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (ABCC2) antibody
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 2 (Abcc2) antibody
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 2 (Abcc2) antibody
  • Abc30 antibody
  • AI173996 antibody
  • Cmoat antibody
  • cMRP antibody
  • DJS antibody
  • Mrp2 antibody

Protein level used designations for ABCC2

ATP-binding cassette sub-family C member 2 , canalicular multidrug resistance protein , canalicular multispecific organic anion transporter 1 , multidrug resistance-associated protein 2 , multidrug resistance protein 2 , ATP-binding cassette, sub-family C (CFTR/MRP), member 2 , calicular multispecific organic anion transporter , multidrug resistance associated protein 2

GENE ID SPECIES
1244 Homo sapiens
12780 Mus musculus
25303 Rattus norvegicus
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