You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) Antibodies

The protein encoded by ABCC3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCC3 Kits (14) and ABCC3 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCC3 8714 O15438
ABCC3 76408 B2RX12
ABCC3 140668 O88563
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-ABCC3 Antibodies at antibodies-online.com

Showing 10 out of 73 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ABCC3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB ABCC3 Antibody (Center) (ABIN654103) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB ABCC3 Antibody (Center) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. ABCC3 antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCC3 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated IHC (fro), IF, WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated IP, WB Western blot analysis of MRP3 expression in HepG2 (A), MCF7 (B), MDAMB435 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Mouse Un-conjugated IHC (fro), IF, WB   500 μL Log in to see 11 to 16 Days
$536.07
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Mouse Un-conjugated ICC, IHC (fro), FACS, WB   1000 μL Log in to see 8 to 10 Days
$881.83
Details

ABCC3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
, ,
,
, , , , , , , , , , , , , ,
Mouse (Murine) , ,
,

, , , , , , , , , , ,
Rat (Rattus) , ,


, , , , , , , , , , ,

Top referenced anti-ABCC3 Antibodies

  1. Human Polyclonal ABCC3 Primary Antibody for EIA, IHC (p) - ABIN950200 : Hoffman, Urbatsch, Vogel: Nucleotide binding to the human multidrug resistance protein 3, MRP3. in The protein journal 2010 (PubMed)
    Show all 5 references for ABIN950200

  2. Human Monoclonal ABCC3 Primary Antibody for IHC (fro), IF - ABIN1105171 : Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997 (PubMed)
    Show all 2 references for ABIN1105171

  3. Human Polyclonal ABCC3 Primary Antibody for FACS, IHC (p) - ABIN654103 : Moyer, Sun, Batzler, Li, Schaid, Yang, Weinshilboum: Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy. in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2010 (PubMed)

  4. Human Polyclonal ABCC3 Primary Antibody for WB - ABIN2781505 : Müller, Asher, Heled, Cohen, Risch, Rund: Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups. in Leukemia research 2008 (PubMed)

More Antibodies against ABCC3 Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) interaction partners

  1. ABCC3 rs4148416 polymorphism was significantly associated with poor osteosarcoma response.

  2. Data suggest that hepatic expression of MRP3 is up-regulated and canalicular localization of MRP2 (show ABCC2 Antibodies) is altered in pediatric patients with advanced nonalcoholic steatohepatitis; these alterations may be involved in changes observed in drug metabolism.

  3. ABCC3 expression may serve as a marker for MDR and predictor for poor clinical outcome of NSCLC.

  4. A functional Nrf2 (show GABPA Antibodies) response element within the eighth intron of the ABCC3 gene.

  5. Renal function of MRP3 is related to renal cell proliferation and cyst formation and that restoring MRP3 may be an effective therapeutic approach for polycystic kidney disease.

  6. These results suggest that carboplatin and paclitaxel may induce drug resistance mediated by MDR1 (show TBC1D9 Antibodies) and MRP3, which may be enhanced by the simultaneous use of both drugs.

  7. ABCC3 promoter methylation does not seem to exhibit any impact on maximum platelet aggregation and clopidogrel response at all

  8. Epidermal growth factor (show EGF Antibodies) - mediated epithelial-mesenchymal transition induces ABCC3 mRNA in MDA-MB-468 breast cancer cells. The process is calcium dependant.

  9. Our data suggest that besides bodyweight, OCT1 (show POU2F1 Antibodies) and ABCC3 genotypes play a significant role in the pharmacokinetics of intravenous morphine and its metabolites in children

  10. for ABCC3 variants, little evidence, if any, was found for an association of drug response to genetic variants

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3 (ABCC3) interaction partners

  1. data show that this transporter activity is involved in ABCC3-induced senescence, demonstrating that this protein has a complex role in cancer, since its loss of function may promote escape from OIS and tumor formation

  2. Transport of cefadroxil by ABCC3 and ABCC4 (show ABCC4 Antibodies) was saturable with K(m) values of 2.5 +/- 0.7 and 0.25 +/- 0.07 mM, respectively.

  3. role of the bile acid membrane transporter Mrp3 (Abcc3), which is expressed in the liver and gut (show GUSB Antibodies), in the hepatic growth response elicited by bile acids and in liver regeneration after partial hepatectomy

  4. Both Abcc2 (show ABCC2 Antibodies) and Abcc3 significantly influenced the PK properties of MTX (show MTX1 Antibodies).

  5. InsP(3)R2-mediated Ca(2 (show CA2 Antibodies)+) signals enhance organic anion secretion into bile by targeting Mrp2 (show ABCC2 Antibodies) to the canalicular membrane.

  6. Data show that Abcc2 (show ABCC2 Antibodies), Abcc3, and Abcg2 (show ABCG2 Antibodies) together mediate the rapid elimination of MTX (show MTX1 Antibodies) and 7OH-MTX (show MTX1 Antibodies).

  7. These results suggest that Mrp3 plays major roles in the efflux transport of various glucuronide conjugates from the enterocytes to the portal blood in the small intestine together with unknown transporter(s)

  8. induction of Mrp3 plays a significant role in hepatocyte protection during obstructive cholestasis

  9. VDR (show CYP27B1 Antibodies) has a role in the protection of colon cells from bile acid toxicity through regulation of the Mrp3 expression

  10. Mrp3 does not have a major role in bile salt physiology, but is involved in the transport of glucuronidated compounds, which could include glucuronidated bile salts in humans

ABCC3 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined\; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described\; however, not all variants have been fully characterized.

Gene names and symbols associated with ABCC3

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (ABCC3) antibody
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (Abcc3) antibody
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 3 (Abcc3) antibody
  • 1700019L09Rik antibody
  • ABC31 antibody
  • cMOAT2 antibody
  • EST90757 antibody
  • Mlp2 antibody
  • MOAT-D antibody
  • Mrp3 antibody

Protein level used designations for ABCC3

ATP-binding cassette sub-family C member 3 , canalicular multispecific organic anion transporter 2 , canicular multispecific organic anion transporter , multi-specific organic anion transporter D , multidrug resistance associated protein , multidrug resistance-associated protein 3 , ATP-binding cassette protein C3 , ATP-binding cassette transporter , transporter , ATP-binding cassette, sub-family C (CFTR/MRP), member 3 , MLP-2 , MRP-like protein 2 , multidrug resistance protein 3 , organic anion transporter

GENE ID SPECIES
8714 Homo sapiens
76408 Mus musculus
140668 Rattus norvegicus
Selected quality suppliers for anti-ABCC3 (ABCC3) Antibodies
Did you look for something else?