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The protein encoded by ABCC5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCC5 Proteins (4) and ABCC5 Kits (2) and many more products for this protein.
Showing 10 out of 85 products:
Human Monoclonal ABCC5 Primary Antibody for IHC (fro), IF - ABIN1105175
Borst, de Wolf, van de Wetering: Multidrug resistance-associated proteins 3, 4, and 5. in Pflügers Archiv : European journal of physiology 2007
Show all 3 references for ABIN1105175
Human Monoclonal ABCC5 Primary Antibody for IHC (fro), IF - ABIN1105176
Kool, de Haas, Scheffer, Scheper, van Eijk, Juijn, Baas, Borst: Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. in Cancer research 1997
Show all 2 references for ABIN1105176
Human Monoclonal ABCC5 Primary Antibody for IHC (fro), IF - ABIN1105177
Scheffer, Kool, Heijn, de Haas, Pijnenborg, Wijnholds, van Helvoort, de Jong, Hooijberg, Mol, van der Linden, de Vree, van der Valk, Elferink, Borst, Scheper: Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies. in Cancer research 2000
Show all 2 references for ABIN1105177
Cow (Bovine) Polyclonal ABCC5 Primary Antibody for EIA, IHC (p) - ABIN375007
Meyer Zu Schwabedissen, Grube, Heydrich, Linnemann, Fusch, Kroemer, Jedlitschky et al.: Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular ... in The American journal of pathology 2005
Human Polyclonal ABCC5 Primary Antibody for FACS, IHC (p) - ABIN652519
Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006
genetic association study in population in Mexico: Data suggest SNPs in ABCC5 (3933+313T>C) are not associated with adverse reactions to methotrexate; they protect against myelosuppression in pediatric patients with ALL (acute lymphoblastic leukemia).
We identified several genes (FasL (show FASL Antibodies), MSH2 (show MSH2 Antibodies), ABCC5, CASP3 (show CASP3 Antibodies), and CYP3A4 (show CYP3A4 Antibodies))that showed association with PFS in patients with osteosarcoma. These pharmacogenetic risk factors might be useful to predict treatment outcome
ABCC5 is a general glutamate (show GRIN1 Antibodies) conjugate and analog transporter that affects the disposition of endogenous metabolites, toxins, and drugs.
The present study investigated the time course and dose dependency of the induction of three efflux proteins, P-gp (show ABCB4 Antibodies), MRP1 (show MDM4 Antibodies) and MRP5, in response to gemcitabine exposure in Capan-2 pancreatic cancer cell line at transcriptional and translational levels.
cCMP is a substrate for MRP5
The blockade of ABC transporter (show ABCG2 Antibodies) MRP5 could help to improve drug effectiveness, reduce tumour growth and prevent recurrence in glioblastoma multiforme.
To identify substrates of orphan transporter ATP-binding cassette subfamily C (show CYP Antibodies) member 5 (ABCC5), identified a class of metabolites, N-lactoyl-amino acids, and found that a protease, cytosolic nonspecific dipeptidase 2 (CNDP2 (show CNDP2 Antibodies)), catalyzes their formation.
ABCC5 transporter is a novel type 2 diabetes susceptibility gene in European and African American populations.
ABCC5 functions as a mediator of breast cancer skeletal metastasis. ABCC5 expression in breast cancer cells is important for efficient osteoclast-mediated bone resorption.
Further research is needed to clarify whether MRP5 is indicative of malignant pathological features in meningiomas and whether possible therapeutic implications exist
Deficiency of MKP5 (show DUSP10 Antibodies) resulted in increased inflammatory activation in macrophages. These findings thus demonstrate that MKP5 (show DUSP10 Antibodies) critically controls inflammation in white adipose tissue and the development of metabolic disorders
Reduced cGMP export as a consequence of decreased MRP5 expression can attenuate heart failure in sepsis.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected\; however, the complete sequence and translation initiation site is unclear.
ATP-binding cassette sub-family C member 5
, canalicular multispecific organic anion transporter C
, multi-specific organic anion transporter C
, multidrug resistance-associated protein 5
, ATP-binding cassette, sub-family C (CFTR/MRP), member 5a
, ATP-binding cassette, sub-family C (CFTR/MRP), member 5b
, ATP-binding cassette, sub-family C, member 5
, ATP-binding cassette sub-family C (CFTR/MRP) member 5a
, ATP-binding cassette, sub-family C (CFTR/MRP), member 5