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anti-ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6) Antibodies

The protein encoded by ABCC6 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCC6 Proteins (10) and ABCC6 Kits (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCC6 368 O95255
ABCC6 27421 Q9R1S7
Anti-Rat ABCC6 ABCC6 81642 O88269
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Top anti-ABCC6 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ABCC6 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rat Un-conjugated IHC (fro), FACS, IF, IHC (p), WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rat Un-conjugated IHC (fro), IF, WB   1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ABCC6 is approximately 0.03ng/ml as a capture antibody. Western Blot detection against Immunogen (36.74 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rat Un-conjugated IHC (fro), IF, IHC (p), WB   1 mL Log in to see 11 to 16 Days
$833.80
Details
Human Rat Un-conjugated IHC (fro), IF, WB   1 mL Log in to see 11 to 16 Days
$833.80
Details
Human Rat Un-conjugated ICC, IHC (fro), FACS, WB   1000 μL Log in to see 8 to 10 Days
$881.83
Details
Human Rat Un-conjugated ICC, IHC, WB   1000 μL Log in to see 8 to 10 Days
$881.83
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Mouse Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details

ABCC6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human
, ,
,
Mouse (Murine)


Top referenced anti-ABCC6 Antibodies

  1. Human Monoclonal ABCC6 Primary Antibody for ELISA, WB - ABIN394570 : Zarbock, Hendig, Szliska, Kleesiek, Götting: Analysis of MMP2 promoter polymorphisms in patients with pseudoxanthoma elasticum. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 5 references for ABIN394570

  2. Human Monoclonal ABCC6 Primary Antibody for IHC (fro), IF - ABIN1105180 : Bergen, Plomp, Schuurman, Terry, Breuning, Dauwerse, Swart, Kool, van Soest, Baas, ten Brink, de Jong: Mutations in ABCC6 cause pseudoxanthoma elasticum. in Nature genetics 2000 (PubMed)
    Show all 2 references for ABIN1105180

  3. Human Monoclonal ABCC6 Primary Antibody for ELISA, WB - ABIN559915 : Pinckard, Sheehan, Schreiber: Ligand-induced formation of p55 and p75 tumor necrosis factor receptor heterocomplexes on intact cells. in The Journal of biological chemistry 1997 (PubMed)
    Show all 2 references for ABIN559915

  4. Human Monoclonal ABCC6 Primary Antibody for IHC (fro), FACS - ABIN1105178 : Scheffer, Hu, Pijnenborg, Wijnholds, Bergen, Scheper: MRP6 (ABCC6) detection in normal human tissues and tumors. in Laboratory investigation; a journal of technical methods and pathology 2002 (PubMed)
    Show all 2 references for ABIN1105178

More Antibodies against ABCC6 Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6) interaction partners

  1. Pseudoxanthoma elasticum is due to mutation of the ABCC6 gene on chromosome 16.

  2. Membrane insertion and topology of the amino-terminal domain TMD0 of multidrug-resistance associated protein 6

  3. A direct relationship between reduced ABCC6 levels and the expression of pro-mineralization genes in hepatocytes.

  4. Minimal rescue of the morpholino-induced phenotype was achieved with eight of the nine mutant human ABCC6 mRNAs tested, implying pathogenicity. This study demonstrates that the Chinese PXE population harbors unique ABCC6 mutations.

  5. Virtual screening expands this possibility to explore more compounds that can interact with ABCC6, and may aid in understanding the mechanisms leading to pseudoxanthoma elasticum

  6. The increase in ABCC6 expression accompanied by the induction of cholesterol biosynthesis supposes a functional role for ABCC6 in human lipoprotein and cholesterol homeostasis.

  7. ABCC6 gene is important to determine the genotype of patients diagnosed with pseudoxanthoma elasticum.

  8. Hepatic ABCC6-mediated ATP release is the main source of circulating PPi, revealing an unanticipated role of the liver in systemic PPi homeostasis.

  9. This study describes the URG7 expression in E.coli and a structural study of it by using circular dichroism and fluorescence spectroscopy.

  10. This study showed that the expression of ABCC6 in liver is an important determinant of calcification in cardiac tissues in response to injuries

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6) interaction partners

  1. bisphosphonates may be helpful for prevention of mineral deposits in Pseudoxanthoma elasticum and generalized arterial calcification of infancy caused by mutations in the ABCC6 gene.

  2. In a mouse model of CKD, ABCC6 protein expression was decreased in liver and kidney, however mRNA levels were unchanged.

  3. In the Abcc6(-/-) genotype, dermal fibroblasts actively contribute to changes that promote matrix calcification; these cells can be further modulated with time by the calcified environment, contributing to the age-dependent progression.

  4. This study showed that the expression of ABCC6 in liver is an important determinant of calcification in cardiac tissues in response to injuries

  5. Magnesium oxide reduces carotid intima media thickness in Abcc6-/- mouse model for pseudoxanthoma elasticum.

  6. Studied the role of genetic modulation and the role of diet in nephrocalcinosis using two established mouse models of ectopic mineralization, Abcc6(tm1Jfk) and Enpp1 (show ENPP1 Antibodies)(asj (show ARSJ Antibodies)) mice.

  7. Report lower elasticity and increased myogenic tone without major changes in agonist-dependent contraction in aged Abcc6(-/-) mouse model of pseudoxanthoma elasticum.

  8. the development of cardiac hypertrophy in the 24-month-old Abcc6(-/-) mice suggests that old pseudoxanthoma elasticum patients might be prone to developing late cardiopathy.

  9. ABCC6 is in the basolateral membrane, mediating the sinusoidal efflux of a metabolite from the hepatocytes to systemic circulation.

  10. A single-nucleotide polymorphism in the Abcc6 gene associates with connective tissue mineralization in mice similar to targeted models for pseudoxanthoma elasticum.

ABCC6 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). The encoded protein, a member of the MRP subfamily, is involved in multi-drug resistance. Mutations in this gene cause pseudoxanthoma elasticum. Alternatively spliced transcript variants that encode different proteins have been described for this gene.

Gene names and symbols associated with ABCC6

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (ABCC6) antibody
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (Abcc6) antibody
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 6 (Abcc6) antibody
  • ABC34 antibody
  • Abcc1b antibody
  • ARA antibody
  • DCC antibody
  • dyscalc antibody
  • Dyscalc1 antibody
  • EST349056 antibody
  • GACI2 antibody
  • MLP1 antibody
  • MOAT-E antibody
  • MOATE antibody
  • Mrp6 antibody
  • PXE antibody
  • PXE1 antibody
  • URG7 antibody

Protein level used designations for ABCC6

ATP-binding cassette sub-family C member 6 , anthracycline resistance-associated protein , multi-specific organic anion transporter E , multidrug resistance-associated protein 6 , ATP-binding cassette, sub-family C, member 6 , multidrug resistance-associated protein-6 , ATP-binding cassette, sub-family C (CFTR/MRP), member 6 , MLP-1 , MRP-like protein 1 , liver multidrug resistance-associated protein 6

GENE ID SPECIES
368 Homo sapiens
27421 Mus musculus
81642 Rattus norvegicus
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