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anti-ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2) Antibodies

The protein encoded by Abcd2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping Abcd2 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Abcd2 225 Q9UBJ2
Abcd2 26874 Q61285
Anti-Rat Abcd2 Abcd2 84356 Q9QY44
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Top anti-Abcd2 Antibodies at antibodies-online.com

Showing 10 out of 24 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ABCD2 Antibody (Center) in mouse brain tissue lysates (35 µg/lane). ABCD2 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB ABCD2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ABCD2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. ABCD2 Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

Abcd2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,

, , , , ,
Mouse (Murine)


Top referenced anti-Abcd2 Antibodies

  1. Human Polyclonal Abcd2 Primary Antibody for EIA, WB - ABIN950204 : Saito, Kawamoto, Kamatani: Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. in Journal of human genetics 2009 (PubMed)
    Show all 3 references for ABIN950204

  2. Human Polyclonal Abcd2 Primary Antibody for EIA, WB - ABIN950203 : Maier, Mayerhofer, Asheuer, Köhler, Rothe, Muntau, Roscher, Holzinger, Aubourg, Berger: X-linked adrenoleukodystrophy phenotype is independent of ABCD2 genotype. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN950203

More Antibodies against Abcd2 Interaction Partners

Human ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2) interaction partners

  1. 13-cis (show CISH Antibodies)-retinoic acid induces ABCD2 expression in human monocytes/macrophages.

  2. ABCD2 has a role, but not a strong one, in risk of early recurrent events after transient ischemic attack

  3. results show that although patients with ABCD2 score greater than 4 were more likely to develop recurrent TIA/CVA in short term, those with lesser score still harbour a considerable risk for TIA/CVA

  4. The transcriptional activity of the ABCD2 promoter was strongly increased by ectopic expression of beta-catenin (show CTNNB1 Antibodies) and TCF-4 (show TCF4 Antibodies).

  5. LXRalpha (show NR1H3 Antibodies) is a negative modulator of Abcd2, acting through a novel regulatory mechanism involving overlapping SREBP and LXRalpha (show NR1H3 Antibodies) binding sites

  6. Testosterone metabolites increased expression of ABCD2 mRNA in fibroblasts from X-linked adrenoleukodystrophy patients.

  7. These findings are of particular importance for the attempt of pharmacological induction of ABCD2 as a possible therapeutic approach in X-linked adrenoleukodystrophy.

  8. LDRP (ABCD2) interacts with both farnesylated wild-type and farnesylation-deficient mutant PEX19 (show PEX19 Antibodies). This interaction is mediated by amino acids 1-218 of ALDRP.

  9. ALDRP interacts with PMP70 (show ABCD3 Antibodies). This interaction occurs via the ALDRP C-terminus [374-740] and the PMP70 (show ABCD3 Antibodies) C-terminus [338-659]. This interaction was demonstrated using human PMP70 (show ABCD3 Antibodies) and mouse ALDRP.

  10. ALDRP interacts with PEX19 (show PEX19 Antibodies) splice variants PEX19 (show PEX19 Antibodies)-delta-E2 and PEX19 (show PEX19 Antibodies)-delta-E8.

Mouse (Murine) ATP-Binding Cassette, Sub-Family D (ALD), Member 2 (Abcd2) interaction partners

  1. Abcd2 is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1 (show ABCD1 Antibodies)-deficient mice

  2. The absence of ABCD2 altered expression of gene clusters associated with lipid metabolism, including PPARalpha (show PPARA Antibodies) signaling.

  3. ABCD2 is a sterol regulatory element binding protein (show CNBP Antibodies) target gene that is highly abundant in fat and opposes the accumulation of dietary lipids generally absent from the triglyceride storage pool within adipose tissue.

  4. Evidence against the adrenoleukodystrophy-related gene acting as a modifier of X-adrenoleukodystrophy.

  5. LXRalpha (show NR1H3 Antibodies) is a negative modulator of Abcd2, acting through a novel regulatory mechanism involving overlapping SREBP and LXRalpha (show NR1H3 Antibodies) binding sites

  6. Abcd1 (show ABCD1 Antibodies) and Abcd2 gene silencing sensitizes astrocytes for inflammation and may have a role in X-adrenoleukodystrophy

  7. ABCD2 plays a role in th degradation of long-chain saturated and omega9-monounsaturated fatty acids and in the synthesis of docosahexanoic acid.

Abcd2 Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown\; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis.

Gene names and symbols associated with Abcd2

  • ATP-binding cassette, sub-family D (ALD), member 2 (ABCD2) antibody
  • ABC transporter D family protein (abcD2) antibody
  • ATP-binding cassette, sub-family D (ALD), member 2 (abcd2) antibody
  • ATP-binding cassette, sub-family D (ALD), member 2 (Abcd2) antibody
  • ATP-binding cassette, subfamily D (ALD), member 2 (Abcd2) antibody
  • ABC39 antibody
  • ALDL1 antibody
  • ALDR antibody
  • ALDRP antibody
  • DDBDRAFT_0214891 antibody
  • DDBDRAFT_0219834 antibody
  • DDB_0214891 antibody
  • DDB_0219834 antibody
  • hALDR antibody

Protein level used designations for Abcd2

ATP-binding cassette, sub-family D, member 2 , ATP-binding cassette, sub-family D (ALD), member 2 , ATP-binding cassette sub-family D member 2 , ATP-binding cassette sub-family D member 2-like , adrenoleukodystrophy-like 1 , adrenoleukodystrophy-related protein , adrenoleukodystrophy related

GENE ID SPECIES
466952 Pan troglodytes
477643 Canis lupus familiaris
526436 Bos taurus
8629134 Dictyostelium discoideum AX4
100413459 Callithrix jacchus
100520309 Sus scrofa
417694 Gallus gallus
697556 Macaca mulatta
100019263 Monodelphis domestica
100433322 Pongo abelii
100549247 Meleagris gallopavo
100556516 Anolis carolinensis
100583742 Nomascus leucogenys
100640478 Amphimedon queenslandica
225 Homo sapiens
26874 Mus musculus
84356 Rattus norvegicus
Selected quality suppliers for anti-Abcd2 (Abcd2) Antibodies
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