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anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) Antibodies

The protein encoded by ABCD1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Kits (11) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCD1 215 P33897
ABCD1 11666 P48410
ABCD1 363516  
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Top anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB ABCD1 Antibody (Center) flow cytometric analysis of HL-60 cells (right... ABCD1 antibody (Center) immunohistochemistry analysis in formalin fixe... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-ABCD1 antibody IHC staining of human pancreas. Immunohistochemist... 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Arabidopsis thaliana Rabbit Un-conjugated WB   100 μL Log in to see 5 to 6 Days
$467.78
Details
Human Mouse Un-conjugated IHC (p)   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit APC FACS, IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$383.17
Details

ABCD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
, ,
Mouse (Murine)
Rat (Rattus)

Top referenced anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Antibodies

  1. Human Polyclonal ABCD1 Primary Antibody for EIA, IHC (p) - ABIN950202 : Xie, Ke, Wang, Huang, Lan: [A novel missense mutation resulting in X-linked adrenoleukodystrophy in female heterozygotes of a Chinese family]. in Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 2010 (PubMed)
    Show all 3 references for ABIN950202

  2. Arabidopsis thaliana Polyclonal ABCD1 Primary Antibody for WB - ABIN334558 : Sun, Suen, Zhang, Liang, Carrie, Whelan, Ward, Hawkins, Jiang, Lim: A dual-targeted purple acid phosphatase in Arabidopsis thaliana moderates carbon metabolism and its overexpression leads to faster plant growth and higher seed yield. in The New phytologist 2012 (PubMed)
    Show all 2 references for ABIN334558

  3. Human Polyclonal ABCD1 Primary Antibody for EIA, WB - ABIN452684 : Höftberger, Kunze, Weinhofer, Aboul-Enein, Voigtländer, Oezen, Amann, Bernheimer, Budka, Berger: Distribution and cellular localization of adrenoleukodystrophy protein in human tissues: implications for X-linked adrenoleukodystrophy. in Neurobiology of disease 2007 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Interaction Partners

Human ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) interaction partners

  1. CCALD is the most common phenotype (64%) in our Chinese patients with X-ALD. Eight novel mutations in the ABCD1 gene identified are disease-causing mutations.

  2. The current study demonstrates that a single splicing mutation affects the ABCD1 transcripts and the ALDP protein function.

  3. both BCAP31 (show BCAP31 Antibodies) and ABCD1 were associated with hepatic cholestasis and death before 1 year. Remarkably, a patient with an isolated deletion at the 3'-end of SLC6A8 (show SLC6A8 Antibodies) had a similar severe phenotype as seen in BCAP31 (show BCAP31 Antibodies) deficiency

  4. Exome sequencing in two brothers with distinct phenotype including congenital language disorder, growth retardation, intellectual disability and urinary and fecal incontinence, identifies missense mutations in ABCD1 and DACH2 (show DACH2 Antibodies).

  5. As a result of loss of ABCD1, there is pathogenic accumulation of very long chain fatty acids which leads to mitochondrial dysfunction.

  6. We detected the same mutation of the ABCD1 gene in two unrelated patients with X-linked adrenoleukodystrophy.

  7. We describe four unrelated women with a late-onset progressive spastic paraparesis and heterozygous mutations in the ABCD1 gene

  8. X-inactivation pattern of the ABCD1 gene is associated with symptomatic status in female X-linked adrenoleukodystrophy carriers.

  9. This study unveil unequivocally that cryptic splicing-induced aberrant messenger-RNA carrying an internal frameshift deletion results from an intronic mutation in the ABCD1 gene.

  10. Array comparative genomic hybridization analysis suggested that the deletion was a genomic rearrangement in the 90-kb span starting in exon 4 and included ABCD1

Mouse (Murine) ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) interaction partners

  1. during the active myelination phase the microsomal fatty acid elongation activity is stimulated in abcd1-deficient mice

  2. Deletion of AMPKalpha1 (show PRKAA1 Antibodies) in the mixed glial cells of Abcd1-KO mice induced spontaneous mitochondrial dysfunction

  3. Abcd2 (show Abcd2 Antibodies) is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice

  4. Data indicate that astrocytes from adrenoleukodystrophy protein Abcd1-/- mice respond sensitively to long-term very-long-chain fatty acids (VLCFA) treatment.

  5. Our data support a link between oxidative stress and the deficiency of Abcd1 or Acox1 (show ACOX1 Antibodies) peroxisomal proteins.

  6. Study demonstrates that oxidative damage to proteins specifically affects five key enzymes of glycolysis and TCA (Tricarboxylic acid) cycle in spinal cords of Abcd1(-) mice.

  7. ALDP facilitates the interaction between peroxisomes and mitochondria, resulting, when ALDP is deficient in X-ALD, in increased VLCFA accumulation

  8. Accumulation of very long-chain fatty acids does not affect mitochindrial function in Abcd1 protein deficiency.

  9. Abcd1 and Abcd2 (show Abcd2 Antibodies) gene silencing sensitizes astrocytes for inflammation and may have a role in X-adrenoleukodystrophy

ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Gene names and symbols associated with ABCD1

  • ATP-binding cassette, sub-family D (ALD), member 1 (abcd1) antibody
  • ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1) antibody
  • ATP-binding cassette sub-family D member 1 (CpipJ_CPIJ013253) antibody
  • ATP-binding cassette sub-family D member 1 (VDBG_05717) antibody
  • ATP-binding cassette sub-family D member 1 (ABCD1) antibody
  • ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1) antibody
  • ATP-binding cassette, subfamily D (ALD), member 1 (Abcd1) antibody
  • WPP domain-containing protein 2 (WPP2) antibody
  • ABC42 antibody
  • ABCD1 antibody
  • Ald antibody
  • Aldgh antibody
  • ALDP antibody
  • AMN antibody
  • F2G19.18 antibody
  • F2G19_18 antibody
  • RGD1562128 antibody
  • WPP domain protein 2 antibody
  • zgc:172102 antibody

Protein level used designations for ABCD1

ATP-binding cassette, sub-family D (ALD), member 1 , adrenoleukodystrophy protein , ATP-binding cassette sub-family D member 1 , ATP-binding cassette sub-family D member 1-like , ATP-binding cassette, sub-family D, member 1 , X-linked adrenoleukodystrophy (ALD) gene homolog

GENE ID SPECIES
495468 Xenopus laevis
515178 Bos taurus
566367 Danio rerio
612520 Canis lupus familiaris
696794 Macaca mulatta
6046470 Culex quinquefasciatus
9531595 Verticillium alfalfae VaMs.102
100328741 Oryctolagus cuniculus
100493545 Xenopus (Silurana) tropicalis
100519529 Sus scrofa
100027916 Monodelphis domestica
100586126 Nomascus leucogenys
215 Homo sapiens
11666 Mus musculus
363516 Rattus norvegicus
841123 Arabidopsis thaliana
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