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ATP-Binding Cassette, Sub-Family D (Ald), Member 4 Proteins (ABCD4)

The protein encoded by ABCD4 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family D (Ald), Member 4 Antibodies (47) and ATP-Binding Cassette, Sub-Family D (Ald), Member 4 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ABCD4 5826 O14678
ABCD4 19300 O89016
Rat ABCD4 ABCD4 299196  
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Top ATP-Binding Cassette, Sub-Family D (Ald), Member 4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ABCD4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

More Proteins for ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) Interaction Partners

Human ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) interaction partners

  1. Results propose a model whereby membrane-bound LMBD1 (show LMBRD1 Proteins) and ABCD4 facilitate the vectorial delivery of lysosomal vitamin B12 (show NDUFB3 Proteins) to cytoplasmic MMACHC (show MMACHC Proteins).

  2. mutations altering the putative ATPase (show ATP13A2 Proteins) domain of ABCD4 affect its function, suggesting that the ATPase activity of ABCD4 may be involved in intracellular processing of vitamin B12 (show NDUFB3 Proteins).

  3. Defects in ABCB4 (show ABCB4 Proteins) have been found to cause progressive familial intrahepatic cholestasis type 3.

Mouse (Murine) ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) interaction partners

  1. P70R resides in the ER but not the peroxisomal membranes, and the hydrophobic property of NH(2)-terminal region determines the subcellular localization of ABC subfamily D proteins.

ATP-Binding Cassette, Sub-Family D (Ald), Member 4 (ABCD4) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown. However, it is speculated that it may function as a heterodimer for another peroxisomal ABC transporter and, therefore, may modify the adrenoleukodystrophy phenotype. It may also play a role in the process of peroxisome biogenesis. Alternative splicing results in at least two different transcript variants, one which is protein-coding and one which is probably not protein-coding.

Gene names and symbols associated with ABCD4

  • ATP-binding cassette, sub-family D (ALD), member 4 (ABCD4)
  • ATP-binding cassette, sub-family D (ALD), member 4 (Abcd4)
  • ATP-binding cassette, sub-family D (ALD), member 4 (abcd4)
  • ATP-binding cassette, subfamily D (ALD), member 4 (Abcd4)
  • ABC41 protein
  • ABCD4 protein
  • EST352188 protein
  • MAHCJ protein
  • P69r protein
  • P70R protein
  • P79R protein
  • PMP69 protein
  • Pxmp1l protein
  • zgc:153503 protein

Protein level used designations for ABCD4

ATP-binding cassette, sub-family D (ALD), member 4 , ATP-binding cassette, sub-family D, member 4 , ATP-binding cassette sub-family D member 4-like , 69 kDa peroxisomal ABC-transporter , ATP-binding cassette sub-family D member 4 , PMP70-related protein , PXMP1-L , peroxisomal membrane protein 69 , PMP69 , peroxisomal membrane protein, 70 kDa-related

GENE ID SPECIES
423349 Gallus gallus
453032 Pan troglodytes
699380 Macaca mulatta
100412514 Callithrix jacchus
100450774 Pongo abelii
100479969 Ailuropoda melanoleuca
5826 Homo sapiens
490781 Canis lupus familiaris
528646 Bos taurus
19300 Mus musculus
767748 Danio rerio
299196 Rattus norvegicus
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