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The protein encoded by ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCG1 Kits (37) and ABCG1 Proteins (9) and many more products for this protein.
Showing 10 out of 92 products:
Human Monoclonal ABCG1 Primary Antibody for ELISA - ABIN394690
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN394690
Human Polyclonal ABCG1 Primary Antibody for FACS, IF - ABIN2157528
Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis. in Cell metabolism 2013
Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (show SCARB1 Antibodies) or ABCG1 but not ABCA1 (show ABCA1 Antibodies).
Our results indicated that genetic variants of ABCG1 may be predictors of survival of nonsmall-cell lung cancer patients
This review focuses on the role of ABC (show ABCB6 Antibodies) transporters A1 and G1 in the pathogenesis of atherosclerosis
Leu at position 550/562 in mABCG1/hABCG1 is critical for their plasma membrane localization but not for ABCG1-mediated cholesterol efflux.
ABCG1 polymorphisms are associated with reduced risk of developing ischemic stroke in hypertriglyceridemic population and atherothrombotic stroke in this cohort of Chinese Han population.
Data suggest that ligand-induced activation of RAGE (advanced glycosylation end product-specific receptor (show AGER Antibodies)) down-regulates ABCG1-mediated cholesterol efflux from macrophages leading to diabetic angiopathies and atherosclerotic plaques.
Propofol up-regulates expression of ABCA1 (show ABCA1 Antibodies), ABCG1, and SR-B1 (show SCARB1 Antibodies) through the PPARgamma (show PPARG Antibodies)/LXRalpha (show NR1H3 Antibodies) pathway in THP-1 (show GLI2 Antibodies) macrophage-derived foam cells.
Expression analysis revealed an association between ABCG1 methylation and lipid levels that might be partly mediated by ABCG1 expression.
HUWE1 (show HUWE1 Antibodies) and NEDD4-1 (show NEDD4 Antibodies) are two E3 ligases that are fundamental enzymes in the post-translational regulation of ABCG1 and ABCG4 (show ABCG4 Antibodies) protein levels and cellular cholesterol export activity
These findings indicate that SNP rs1893590 of ABCG1 has a significant impact over HDL (show HSD11B1 Antibodies)-C under asymptomatic clinical conditions in an age and BMI dependent way.
ABCG1 promoter rs57137919G>A variant had an allele-specific effect on ABCG1 expression and was associated with an increased apoptosis in cholesterol-loaded macrophages.
3beta,5alpha,6beta-cholestanetriol and 25-hydroxycholesterol are physiologic substrates for ABCG1
Our data suggest that GLP-1 (show GCG Antibodies)-based therapy modulate ABCA1 (show ABCA1 Antibodies)/ABCG1 expression in adipocytes potentially through an LXR-alpha (show NR1H3 Antibodies) mediated process.
The absence of ABCG1 inhibits tumour growth through modulation of macrophage function within the tumour, and illustrates a link between cholesterol homeostasis and cancer.
data support the impact of genes from the Abcg1-U2af1 (show U2AF1 Antibodies) region as modifiers of Tc1 (show C8orf4 Antibodies)-dependent memory and locomotor phenotypes in Tc1 (show C8orf4 Antibodies) mouse model of Down syndrome.
HDL (show HSD11B1 Antibodies) enhances transendothelial cholesterol transport by activation of a mechanism involving ABCA1 (show ABCA1 Antibodies), ABCG1 and SR-B1 (show SCARB1 Antibodies) but not involving PI3K and Akt (show AKT1 Antibodies).
AOPPs increase accumulation of lipids and exacerbate atherosclerosis through downregulation of ABCA1 (show ABCA1 Antibodies) and ABCG1 expression, and the JAK (show JAK3 Antibodies)-LXRalpha (show NR1H3 Antibodies) signaling pathway in apoE (show APOE Antibodies)-KO mice.
The role of cellular cholesterol transport proteins including adenosine triphosphate binding cassette transporter A1 (ABCA1 (show ABCA1 Antibodies)), G1 (ABCG1) and scavenger receptor class B type I (SR-BI) in diabetic nephropathy, was determined.
The study identifies a major role of adipocyte ABCG1 in adiposity and fat mass growth and suggests that adipose ABCG1 might represent a potential therapeutic target in obesity.
ABCG1 is involved in cellular vitamin E efflux.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
ATP-binding cassette sub-family G member 1
, ATP-binding cassette, sub-family G (WHITE), member 1
, ATP-binding cassette sub-family G member 1-like
, ABC transporter 8
, ATP-binding cassette transporter 8
, ATP-binding cassette transporter member 1 of subfamily G
, homolog of Drosophila white
, white protein homolog (ATP-binding cassette transporter 8)
, ATP-binding cassette 8
, ATP-binding cassette, subfamily G, member 1
, white protein homolog