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ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 Proteins (ABCG4)

The protein encoded by ABCG4 is included in the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCG4 Antibodies (51) and ABCG4 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ABCG4 64137 Q9H172
Mouse ABCG4 ABCG4 192663  
Rat ABCG4 ABCG4 300664  
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Top ABCG4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ABCG4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

More Proteins for ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4) Interaction Partners

Human ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4) interaction partners

  1. Study suggests that high ABCG4 expression is associated with poor prognosis in patients with non-small-cell lung cancer with advanced stages.

  2. HUWE1 (show HUWE1 Proteins) and NEDD4-1 (show NEDD4 Proteins) are two E3 ligases that are fundamental enzymes in the post-translational regulation of ABCG1 (show ABCG1 Proteins) and ABCG4 protein levels and cellular cholesterol export activity

  3. These results suggest that ABCA1 (show ABCA1 Proteins), ABCG1 (show ABCG1 Proteins), and ABCG4 are localized to distinct membrane meso-domains and disturb the meso-domain structures by reorganizing lipids on the plasma membrane

  4. This study demonstreated that Abcg4 acts in concert with Abcg2 to efflux Abeta (show APP Proteins) from the brain across the blood-brain barrier.

  5. Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4: maps to human chromosome 11, is expressed abundantly in brain, and has alternatively-spliced isoforms

  6. ABCG4 is expressed specifically in the brain and the eye.

  7. ABCG1 (show ABCG1 Proteins) and ABCG4 act in concert with ABCA1 (show ABCA1 Proteins) to maximize the removal of excess cholesterol from cells and to generate cholesterol-rich lipoprotein particles

  8. ABCG4 is highly expressed in microglia on alzheimer disease brain.

  9. Human ABC transporters ABCG2 (BCRP) and ABCG4

  10. ABCG4 may be involved in macrophage lipid homeostasis.

Mouse (Murine) ATP-Binding Cassette, Sub-Family G (WHITE), Member 4 (ABCG4) interaction partners

  1. transplantation of bone marrow deficient in ABCG4, a transporter of unknown function, into Ldlr (show LDLR Proteins)(-/-) mice resulted in thrombocytosis, accelerated thrombosis and atherosclerosis

  2. The loss of ABCG1 (show ABCG1 Proteins) and/or ABCG4 from the CNS results in changes in metabolic pathways and in behavior.

  3. ABCG1 (show ABCG1 Proteins) and ABCG4 promote cholesterol efflux from cells to HDL (show HSD11B1 Proteins)

  4. ABCG1 (show ABCG1 Proteins) and ABCG4 act in concert with ABCA1 (show ABCA1 Proteins) to maximize the removal of excess cholesterol from cells and to generate cholesterol-rich lipoprotein particles

  5. based on the results, we propose that ABCG1 (show ABCG1 Proteins) and ABCG4 mediate the intracellular vesicular transport of cholesterol/sterols within both neurons and astrocytes to regulate cholesterol transport in the brain

  6. a role for Abcg4 in sterastrocyol efflux in the brain, Abcg4 promotes efflux of cholesterol, desmosterol, and possibly other sterol biosynthetic intermediates to HDL (show HSD11B1 Proteins).

ABCG4 Protein Profile

Protein Summary

The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.

Gene names and symbols associated with ABCG4

  • ATP-binding cassette, sub-family G (WHITE), member 4 (ABCG4)
  • ATP-binding cassette, sub-family G (WHITE), member 4 (abcg4)
  • ATP-binding cassette sub-family G member 4 (CpipJ_CPIJ007191)
  • ATP-binding cassette sub-family G member 4 (CpipJ_CPIJ012365)
  • ATP-binding cassette sub-family G member 4 (CpipJ_CPIJ012372)
  • ATP-binding cassette sub-family G member 4 (CpipJ_CPIJ014443)
  • ATP-binding cassette sub-family G member 4 (CpipJ_CPIJ019125)
  • ATP-binding cassette sub-family G member 4 (CpipJ_CPIJ020198)
  • ATP-binding cassette sub-family G member 4 (PAAG_06842)
  • ATP-binding cassette, sub-family G (WHITE), member 4 (Abcg4)
  • ATP-binding cassette, subfamily G (WHITE), member 4 (Abcg4)
  • 6430517O04Rik protein
  • WHITE2 protein

Protein level used designations for ABCG4

ATP-binding cassette, sub-family G (WHITE), member 4 , ATP-binding cassette, subfamily G, member 4 , ATP-binding cassette sub-family G member 4 , ATP-binding cassette, subfamily G, member 4-like , ATP-binding cassette sub-family G member 4-like , putative ABC transporter

GENE ID SPECIES
428242 Gallus gallus
466802 Pan troglodytes
508443 Bos taurus
550918 Apis mellifera
564842 Danio rerio
6039746 Culex quinquefasciatus
6046116 Culex quinquefasciatus
6046125 Culex quinquefasciatus
6047536 Culex quinquefasciatus
6053250 Culex quinquefasciatus
6054483 Culex quinquefasciatus
9094554 Paracoccidioides sp. 'lutzii' Pb01
100338027 Oryctolagus cuniculus
100451383 Pongo abelii
100550413 Meleagris gallopavo
100595528 Nomascus leucogenys
64137 Homo sapiens
610604 Canis lupus familiaris
192663 Mus musculus
100518504 Sus scrofa
300664 Rattus norvegicus
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