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Metallocarboxypeptidase that mediates deglutamylation of target proteins. Additionally we are shipping AGBL4 Antibodies (13) and AGBL4 Proteins (2) and many more products for this protein.
AGBL4 promoter hypermethylation is associated with Colorectal Cancer.
Nna1 (show AGTPBP1 ELISA Kits) and CCP4 (show AGBL1 ELISA Kits) remove the C-terminal glutamate (show GRIN1 ELISA Kits) from substrates with two or more glutamates, whereas CCP6 requires four or more glutamates. CCP4 (show AGBL1 ELISA Kits) behaves as a promiscuous glutamase with little preference for chain length or neighboring amino acid composition
study shows that Mad2 (show MXI1 ELISA Kits) is a novel substrate for CCP6 in megakaryocytes; Mad2 (show MXI1 ELISA Kits) polyglutamylation plays a crucial role in the regulation of megakaryopoiesis
Metallocarboxypeptidase that mediates deglutamylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates from the carboxy-terminus of target proteins such as MYLK. Acts as a long-chain deglutamylase and specifically shortens long polyglutamate chains, while it is not able to remove the branching point glutamate, a process catalyzed by AGBL5/CCP5.
cytosolic carboxypeptidase 6
, ATP/GTP binding protein-like 4
, ATP/GTP-binding protein-like 4