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The membrane-associated protein encoded by ABCA8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA8 Antibodies (32) and ABCA8 Proteins (5) and many more products for this protein.
ABCA8 facilitates cholesterol efflux and modulates HDL (show HSD11B1 ELISA Kits)-cholesterol levels.
Genes ABCC7 (show CFTR ELISA Kits), A3, A8, A12 (show UGT1A9 ELISA Kits), and C8 prevailed among the most upregulated or downregulated ones. In conclusion, the results supported our theory about general adenosine triphosphate-binding cassette gene expression profiles and their importance for cancer on clinical as well as research levels
These data suggest a direct relationship between the levels of ABCA8 and the ectopic expression of alpha-syn and increased expression of p25alpha (show Tppp ELISA Kits)
ABCA8 is highly expressed in human brain and regulates lipid metabolism in oligodendrocytes, potentially playing a role in myelin formation and maintenance.
SLC2A1/GLUT1 (show SLC2A1 ELISA Kits), SLC1A3/EAAT1 (show SLC1A3 ELISA Kits), and SLC1A2/EAAT2 (show SLC1A2 ELISA Kits) were the main SLC (show CCL21 ELISA Kits) proteins whereas ABCG2/BCRP (show ABCG2 ELISA Kits), ABCB1/MDR1 (show ABCB4 ELISA Kits), ABCA2 (show ABCA2 ELISA Kits) and ABCA8 were the main ABC (show ABCB6 ELISA Kits) quantified in isolated brain microvessels
Functional analysis of the transport properties of ABCA8.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. The function of this protein has not yet been determined.
ATP-binding cassette, sub-family A (ABC1), member 8
, ATP-binding cassette, sub-family A (ABC1), member 8b
, ATP-binding cassette, sub-family A (ABC1), member 8a
, ATP-binding cassette sub-family A member 8-like
, ATP-binding cassette sub-family A member 8
, ATP-binding cassette sub-family A member 8-B