anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antibodies

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Log in to see 11 to 16 Days
$351.12
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB   500 μL Log in to see 11 to 16 Days
$650.57
Details
Human Mouse Un-conjugated IC, IHC, WB   100 μg Log in to see 11 to 16 Days
$479.29
Details
Hamster Mouse Un-conjugated FACS, IF, IHC, WB   500 μL Log in to see 11 to 16 Days
$623.86
Details
Human Rabbit Un-conjugated IHC   50 μg Log in to see 11 to 16 Days
$688.29
Details
Human Mouse Un-conjugated FACS, IHC, WB   100 μL Log in to see 11 to 16 Days
$688.29
Details
Human Mouse Un-conjugated IC, FACS, IHC, WB   250 μg Log in to see 11 to 16 Days
$771.57
Details
Human Rat Un-conjugated IC, FACS, IHC, WB   125 μg Log in to see 11 to 16 Days
$795.14
Details
Human Mouse Un-conjugated IC, FACS, IHC, WB   125 μg Log in to see 11 to 16 Days
$807.71
Details

ABCB1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , , , ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies

  1. Human Polyclonal ABCB1B Primary Antibody for FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 references for 670161

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Interaction Partners

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Meta-analysis found no evidence for ABCB1 (show ABCB1 Antibodies) C3435T and C1236T polymorphisms as risk factors for pediatric Acute Lymphoblastic Leukemia.

  2. ABCB1 (show ABCB1 Antibodies) gene polymorphisms in association with others risk factors contribute to anti-TB drug resistance, mainly ethambutol.

  3. For the first time, we demonstrated that MDR1 (show TBC1D9 Antibodies) rs1128503 polymorphisms were associated with systemic lupus erythematosus susceptibility in Chinese Guangxi population.

  4. multiple pathways, including MMP9 (show MMP9 Antibodies) cleavage and ubiquitinylation, mediated P-gp (show ABCB4 Antibodies) downmodulation.

  5. We also determined the effect of Pygo2 on the sensitivity of breast tumors resistant to doxorubicin in a mouse model. Finally, RNA samples from 64 paired patient tumors (before and after chemotherapy) highly and significantly overexpressed Pygo2 and/or MDR1 after treatment, thus underlining a pivotal role for the Pygo2-mediated Wnt/b-catenin pathway in the clinical chemoresistance of breast cancer.

  6. We did not find any relationship between the methylation levels of the ABCB1 (show ABCB1 Antibodies) promoter and clopidogrel resistance (CR). In conclusions, our study indicated that ABCB1 (show ABCB1 Antibodies) polymorphisms might be useful in further evaluating the pathogenesis of CR.

  7. A subset of virus-specific CD161 (show KLRB1 Antibodies)(+) T cells selectively express the multidrug transporter MDR1 (show TBC1D9 Antibodies) and are resistant to chemotherapy in acute myeloid leukemia (show BCL11A Antibodies).

  8. Primary CD4 (show CD4 Antibodies)+P-gphigh T cells eliminate intracellular raltegravir more readily than P-gplow cells and HIV-1 viraemia correlates with P-gp (show ABCB4 Antibodies) overall activity; specific CD4 (show CD4 Antibodies)+P-gphigh T cell subsets could facilitate the persistence of viral replication in vivo and ultimately promote the appearance of drug resistance

  9. We observed an association between ABCB1 (show ABCB1 Antibodies) 3435 T/T and lower grade of toxicities (p=0.05) in patients receiving taxanes for breast cancer. No other associations were found for CYP (show PPIG Antibodies) 3A4 *1B, 3A5*3 and ABCB1 (show ABCB1 Antibodies) C1236T.

  10. that residual SWI (show SMARCA1 Antibodies)/SNF (show SNRPA Antibodies) complexes lacking SMARCB1 (show SMARCB1 Antibodies) are vital determinants of drug sensitivity, not just to TOP2A (show TOP2A Antibodies)-targeted agents, but to the much broader range of cancer drugs effluxed by ABCB1 (show ABCB1 Antibodies).

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. the high-affinity site of P-glycoprotein is inaccessible because of either a conformational change or binding of detergent at the binding site in a detergent micelle environment; ligands bind to a low-affinity site, resulting in altered modulation of P-gp (show ABCB4 Antibodies) ATPase (show DNAH8 Antibodies) activity

  2. Data suggest that ATP binding to Abcb1b/P-glycoprotein (Pgp) in liposomes exhibits cooperativity with verapamil (a cardiovascular/antiarrhythmia drug); cooperativity between verapamil and a nonhydrolyzable ATP analog (AMPPNP) leads to distinct global conformational changes in Abcb1b/Pgp.

  3. Chrysosplenetin inhibited P-gp (show ABCB4 Antibodies) activity and reverse the up-regulated P-gp (show ABCB4 Antibodies) and MDR1 (show ABCB4 Antibodies) levels induced by artemisinin.

  4. Tamsulosin and tolterodine with P-gp (show ABCB4 Antibodies) gene expression and activity in an enantiomer-specific way.

  5. Pgp (show ABCB4 Antibodies)-coupled ATPase (show DNAH8 Antibodies) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  6. Data show that human transgenic mutant huntingtin (show HTT Antibodies) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (show ABCB4 Antibodies)) which suggests that MDR1 (show ABCB4 Antibodies) might be a potential therapeutic target for Huntington's disease.

  7. In vitro and in vivo downregulation of the ATP binding cassette transporter (show ABCC3 Antibodies) B1 by the HMG-CoA reductase (show HMGCR Antibodies) inhibitor simvastatin

  8. Efficient chemoprotection of CDD (show CDA Antibodies) and MDR1 (show ABCB4 Antibodies) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (show FOXC1 Antibodies)-C and anthracycline application

  9. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1 (show ABCB1 Antibodies)-1Delta mutant mice following exposure to various P-gp (show ABCB4 Antibodies) substrates.

  10. Data indicate that the brain penetration of ABT-888 in both Abcb1a (show ABCB4 Antibodies)/1b-/- and Abcb1a (show ABCB4 Antibodies)/1b-/-;Abcg2 (show ABCG2 Antibodies)-/- mice was significantly higher than in wild-type mice.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • ABC20 antibody
  • Abcb1 antibody
  • CD243 antibody
  • CLCS antibody
  • GP170 antibody
  • mdr antibody
  • Mdr1 antibody
  • Mdr1b antibody
  • P-GP antibody
  • Pgy-1 antibody
  • Pgy1 antibody

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPECIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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