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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antibodies

The membrane-associated protein encoded by ABCB1B is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB1B 5243 P08183
ABCB1B 18669 P06795
ABCB1B 24646  
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies at antibodies-online.com

Showing 10 out of 31 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody (ABIN670161), Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-MDR1/p-GP/CD243 Polyclonal Antibody , Unconjugated 1:200 at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p) Immunofluorescence analysis of mouse kidney tissue using anti-MDR1 (dilution of primary antibody - 1:1000) Immunohistochemical staining of paraffin embedded mouse kidney tissue using anti-MDR1 (primary antibody at 1:1000) 100 μg Log in to see 9 to 14 Days
$351.12
Details
Human Mouse Un-conjugated IF, IP, WB   100 μL Log in to see 14 Days
$343.75
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB   500 μL Log in to see 11 to 16 Days
$650.57
Details
Human Mouse Un-conjugated IC, IHC, WB   100 μg Log in to see 11 to 16 Days
$479.29
Details
Hamster Mouse Un-conjugated FACS, IF, IHC, WB   500 μL Log in to see 11 to 16 Days
$623.86
Details
Human Rabbit Un-conjugated IHC   50 μg Log in to see 11 to 16 Days
$688.29
Details
Human Mouse Un-conjugated FACS, IHC, WB   100 μL Log in to see 11 to 16 Days
$688.29
Details
Human Mouse Un-conjugated IC, FACS, IHC, WB   250 μg Log in to see 11 to 16 Days
$733.86
Details
Human Rat Un-conjugated IC, FACS, IHC, WB   125 μg Log in to see 11 to 16 Days
$755.86
Details

ABCB1B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antibodies

  1. Human Polyclonal ABCB1B Primary Antibody for FACS, IF (p) - ABIN670161 : Hu, Peng, Li: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer. in Journal of experimental & clinical cancer research : CR 2009 (PubMed)
    Show all 2 references for ABIN670161

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Interaction Partners

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Results find that ABCB1 (show ABCB1 Antibodies) is a target of miR (show MLXIP Antibodies)-9 and reverses the effect of miR (show MLXIP Antibodies)-9-mediated chemoresistance in K562 chronic myelogenous leukemia cells.

  2. findings suggest that osimertinib, a clinically-approved third-generation EGFR (show EGFR Antibodies) TKI, can reverse ABCB1 (show ABCB1 Antibodies)-mediated MDR, which supports the combination therapy with osimertinib and ABCB1 (show ABCB1 Antibodies) substrates may potentially be a novel therapeutic stategy in ABCB1 (show ABCB1 Antibodies)-positive drug resistant cancers.

  3. Subcellular distribution of P-gp (show ABCB4 Antibodies) and subsequent downregulation by pristimerin contribute to overcoming ABCB1 (show ABCB1 Antibodies)-mediated chemotherapeutic drug resistance. Our findings suggested inducing the decrease of P-gp (show ABCB4 Antibodies) membrane protein could be a new promising alternative therapeutic strategy in ABCB1 (show ABCB1 Antibodies)-mediated Multidrug resistance.

  4. Rack1 (show GNB2L1 Antibodies) regulated P-Glycoprotein activity, which was necessary for adriamycin-induced P-Glycoprotein - mediated phosphorylation of Anxa2 (show ANXA2 Antibodies) and Erk1/2 (show MAPK1/3 Antibodies).

  5. we found that the C3435T MDR1 (show TBC1D9 Antibodies) polymorphism does not affect blood levels of cortisol or ACTH (show POMC Antibodies) in healthy Japanese males. The effect size at alpha = 0.05 and at power 0.80 in the present sample size was 0.176 Thus, the present study suggests that the C3435T MDR1 (show TBC1D9 Antibodies) polymorphism does not have a great impact on blood levels of cortisol or ACTH (show POMC Antibodies).

  6. ABCB1 (show ABCB1 Antibodies) 1236C/T variants might play a role in the risk of Parkinson's disease, whereas ABCB1 (show ABCB1 Antibodies) 3435C/T polymorphisms might not contribute to susceptibility to disease (Meta-Analysis)

  7. ABCB1 (show ABCB1 Antibodies) might play a pivotal role in acquisition of taxane resistance.

  8. A pro-apoptotic effect of verapamil was observed in L3.6pl cells, but not in L3.6plGres cells, which was linked to their differential expression of P-gp (show ABCB4 Antibodies) and equilibrative nucleoside transporter-1 (ENT-1 (show SLC29A1 Antibodies)).

  9. Our findings suggest that multidrug resistant osteosarcoma cells are able to spread their ability to resist the effects of doxorubicin treatment on sensitive cells by transferring exosomes carrying MDR-1 (show TBC1D9 Antibodies) mRNA and its product P-glycoprotein.

  10. Methylation of Notch3 (show NOTCH3 Antibodies) modulates chemoresistance via P-glycoprotein

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) interaction partners

  1. Chrysosplenetin inhibited P-gp (show ABCB4 Antibodies) activity and reverse the up-regulated P-gp (show ABCB4 Antibodies) and MDR1 (show ABCB4 Antibodies) levels induced by artemisinin.

  2. Tamsulosin and tolterodine with P-gp (show ABCB4 Antibodies) gene expression and activity in an enantiomer-specific way.

  3. Pgp (show ABCB4 Antibodies)-coupled ATPase (show DNAH8 Antibodies) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  4. Data show that human transgenic mutant huntingtin (show HTT Antibodies) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (show ABCB4 Antibodies)) which suggests that MDR1 (show ABCB4 Antibodies) might be a potential therapeutic target for Huntington's disease.

  5. In vitro and in vivo downregulation of the ATP binding cassette transporter (show ABCC3 Antibodies) B1 by the HMG-CoA reductase (show HMGCR Antibodies) inhibitor simvastatin

  6. Efficient chemoprotection of CDD (show CDA Antibodies) and MDR1 (show ABCB4 Antibodies) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (show FOXC1 Antibodies)-C and anthracycline application

  7. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1 (show ABCB1 Antibodies)-1Delta mutant mice following exposure to various P-gp (show ABCB4 Antibodies) substrates.

  8. Data indicate that the brain penetration of ABT-888 in both Abcb1a (show ABCB4 Antibodies)/1b-/- and Abcb1a (show ABCB4 Antibodies)/1b-/-;Abcg2 (show ABCG2 Antibodies)-/- mice was significantly higher than in wild-type mice.

  9. Expression of Abcb1 (show ABCB1 Antibodies) at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (show NFE2L2 Antibodies).

  10. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1B

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • ABC20 antibody
  • Abcb1 antibody
  • CD243 antibody
  • CLCS antibody
  • GP170 antibody
  • mdr antibody
  • Mdr1 antibody
  • Mdr1b antibody
  • P-GP antibody
  • Pgy-1 antibody
  • Pgy1 antibody

Protein level used designations for ABCB1B

P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1 , ATP-binding cassette sub-family B member 1 , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1

GENE ID SPECIES
5243 Homo sapiens
18669 Mus musculus
24646 Rattus norvegicus
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