ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) ELISA Kits

The protein encoded by ABCC1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCC1 Antibodies (72) and ABCC1 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ABCC1 4363 P33527
ABCC1 17250 O35379
ABCC1 24565 Q8CG09
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Top ABCC1 ELISA Kits at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rat 0.118 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
$932.09
Details
Human 0.082 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Rat 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Mouse
0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$658.90
Details
Guinea Pig 0.094 ng/mL 0.156-10 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Rabbit 75 pg/mL 125-8000 pg/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details

Top referenced ABCC1 ELISA Kits

  1. Human ABCC1 ELISA Kit for Sandwich ELISA - ABIN828375 : Ma, Zhou, Zhang, Li, Li, Ju, Shi, Sun, Zhao, Mu, Yan, Lu: Modulation of drug-resistant membrane and apoptosis proteins of breast cancer stem cells by targeting berberine liposomes. in Biomaterials 2013 (PubMed)

More ELISA Kits for ABCC1 Interaction Partners

Human ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. Visfatin (show NAMPT ELISA Kits) increases the nuclear translocation of Akt (show AKT1 ELISA Kits) and its binding with ABCC1. These data showed that visfatin (show NAMPT ELISA Kits) can decrease doxorubicin sensitivity of Non-small-cell lung cancer cells via activation of Akt (show AKT1 ELISA Kits)/MRP1 (show MDM4 ELISA Kits).

  2. Studied hedgehog (show SHH ELISA Kits) signaling effect thru ATP-binding cassette (ABC (show ABCB6 ELISA Kits)) transporters in hepatoma drug sensitivity. Results suggest Hedgehog (show SHH ELISA Kits) signaling transcription factor Gli-2 (show GLI2 ELISA Kits) to be the primary regulator for drug sensitivity of hepatoma through the ABCC1 transporter.

  3. This study demonstrated that mitochondrial MRP-1 (show MDM4 ELISA Kits) is expressed in the outer mitochondrial membrane and is a client protein of HSP90beta (show HSP90AB1 ELISA Kits).

  4. High ABCC1 expression is associated with hepatic fibrosis.

  5. This study shows direct binding between MRP1 (show MDM4 ELISA Kits) Linker 1 (L1MRP1) domain and alpha- and beta-tubulin (show TUBB ELISA Kits) subunits, using a scanning peptide approach

  6. In summary, chaetominine strongly reverses drug resistance by interfering with the PI3K (show PIK3CA ELISA Kits)/Akt (show AKT1 ELISA Kits)/Nrf2 (show GABPA ELISA Kits) signaling, resulting in reduction of MRP1 (show MDM4 ELISA Kits)-mediated drug efflux and induction of Bax (show BAX ELISA Kits)/Bcl-2 (show BCL2 ELISA Kits)-dependent apoptosis in an ADR (show AKR1B1 ELISA Kits)-resistant K562/Adr (show AKR1B1 ELISA Kits) leukemia cell line.

  7. cross-talk between MRP1 (show MDM4 ELISA Kits) glycosylation and phosphorylation occurs.

  8. meta-analysis results strongly suggest that MRP1 (show MDM4 ELISA Kits) is overexpressed in both neurons and astrocytes of intractable epilepsy patients, inhibition of MRP1 (show MDM4 ELISA Kits) may enhance antiepileptic drug efficacy by increasing local drug availability

  9. Our results show MRP1 (show MDM4 ELISA Kits) as a potential biomarker of resistance to treatment with irinotecan when found in CTCs from mCRC patients.

  10. Taxus chinensis var.-mediated downregulation of MRP1 (show MDM4 ELISA Kits), MDR1, and LRP (show RPSA ELISA Kits) might contribute to the reversal of drug resistance in non-small cell lung cancer stem cells.

Mouse (Murine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. Data, including data from studies in knockout mice, suggest that Mrp1 is involved in development of vascular endothelial dysfunction in diabetic angiopathy; Mrp1 appears to be required for oxidative stress in endothelial cells due to hyperglycemia.

  2. Oxidant-enriched Tumorigenic Endothelial Cells (EOMA) cells survive a heavy oxidant burden by rapid efflux of GSSG, which is lethal if trapped within the cell. A hyperactive MRP-1 system for GSSG efflux acts as a critical survival factor for these cells, making it a potential target for EOMA therapeutics.

  3. P-gp, Bcrp, Mrp1 and Mrp4 are differentially expressed at the outer and inner blood retinal barrier, resulting in an altered ability to limit substrate distribution at the retina as compared with the blood brain barrier

  4. Lentivirus-based RNAi stably knocks down the expression of the Mrp1 gene in the established TM4 (show TPM4 ELISA Kits) sertoli cell line.

  5. neprilysin (show MME ELISA Kits) x ABCC1 double-deficient mice present a new model for early effects of amyloid-beta-related mild cognitive impairment that allows investigations without artificial overexpression of inherited Alzheimer's disease genes

  6. Expression of apoA-I (show APOA1 ELISA Kits) or ABCA1 (show ABCA1 ELISA Kits) can reduce steatosis by decreasing lipid storage in hepatocytes through lipid transport and may also reduce endoplasmic reticulum stress, further lessening hepatic steatosis

  7. Loss of Mrp1 coupled with reductions in steroid hormone levels leads to alterations in extrahepatic phase I, phase II and phase III metabolizing enzymes in a tissue-specific manner.

  8. Cd or H(2)O(2) exposure increased the expression of key transport genes, Mrp1 and Mrp2 (show ABCC2 ELISA Kits), in WT cells but not in metallothionein (show MT ELISA Kits)-null cells.

  9. These results identify Mrp1 as the transporter essential for S1P (show S1PR1 ELISA Kits) efflux from the endothelial cells and thus for inside-out S1P (show S1PR1 ELISA Kits) signaling to P-glycoprotein at the blood-brain and blood-spinal cord barriers.

  10. investigated changes in the expression and activity of multidrug resistance protein 1 and multidrug resistance-associated protein 1 in highly purified lung dendritic cells during aging

Cow (Bovine) ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1) interaction partners

  1. Using electron cryomicroscopy, authors determined the molecular structures of bovine MRP1 in two conformations: an apo (show C9orf3 ELISA Kits) form at 3.5 A without any added substrate and a complex form at 3.3 A with one of its physiological substrates, leukotriene C4; structures show that by forming a single bipartite binding site, MRP1 can recognize a of substrates with different chemical structures.

  2. P-gp (show ABCB4 ELISA Kits), Bcrp (show ABCG2 ELISA Kits) and Mrp1 are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

ABCC1 Antigen Profile

Antigen Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.

Gene names and symbols associated with ABCC1

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (ABCC1) antibody
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1 (Abcc1) antibody
  • ATP-binding cassette, subfamily C (CFTR/MRP), member 1 (Abcc1) antibody
  • ABC29 antibody
  • ABCC antibody
  • Abcc1a antibody
  • Abcc1b antibody
  • Avcc1a antibody
  • GS-X antibody
  • Mdrap antibody
  • Mrp antibody
  • Mrp1 antibody

Protein level used designations for ABCC1

ATP-binding cassette transporter variant ABCC1delta-ex13 , ATP-binding cassette transporter variant ABCC1delta-ex13&14 , ATP-binding cassette transporter variant ABCC1delta-ex25 , ATP-binding cassette transporter variant ABCC1delta-ex25&26 , LTC4 transporter , leukotriene C(4) transporter , multidrug resistance-associated protein 1 , ATP-binding cassette, sub-family C (CFTR/MRP), member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1b , multiple drug resistance-associated protein , ATP-binding cassette sub-family C member 1 , multidrug resistance protein 1 , ATP-binding cassette sub-family C ( CFTR/MRP) member 1a , ATP-binding cassette, sub-family C (CFTR/MRP), member 1

GENE ID SPECIES
4363 Homo sapiens
17250 Mus musculus
403453 Canis lupus familiaris
281588 Bos taurus
395416 Gallus gallus
733619 Sus scrofa
100734674 Cavia porcellus
24565 Rattus norvegicus
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