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anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 3 (ABCD3) Antibodies

The protein encoded by ABCD3 is a member of the superfamily of ATP-binding cassette (ABC) transporters.

list all antibodies Gene Name GeneID UniProt
ABCD3 19299 P55096
ABCD3 5825 P28288
ABCD3 25270 P16970
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Top anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 3 Antibodies at antibodies-online.com

Showing 10 out of 36 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated IHC (p), IHC, ELISA, WB Immunohistochemistry-Paraffin: PMP70 Antibody [NBP1-20871] - 3.8ug/ml staining of paraffin embedded Human Testis. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry-Paraffin: PMP70 Antibody [NBP1-87258] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells. Immunocytochemistry/Immunofluorescence: PMP70 Antibody [NBP1-87258] Staining of human cell line U-2 OS shows positivity in vesicles. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Bat Goat Un-conjugated IHC (p), ELISA, WB Anti-ABCD3 / PMP70 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN962634 concentration 41396 ug/ml. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Mouse Un-conjugated ICC, IF, IHC, IHC (p) Immunohistochemistry: PMP70 Antibody (CL2524) [NBP2-36770] - Staining of human liver shows strong granular cytoplasmic immunoreactivity in hepatocytes. Immunocytochemistry/Immunofluorescence: PMP70 Antibody (CL2524) [NBP2-36770] - Staining in U251 cell line with Anti-ABCD3 monoclonal antibody, showing specific staining of peroxisomes in green. Microtubule- and nuclear probes are visualized in red and blue respectively (where available). Antibody staining is shown in green. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Rabbit Anti-Goat IgG at 1: 5000;  TMB staining Read the data in Microplate Reader by 450nm. Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti-PXMP1/ABCD3/PMP70 Polyclonal Antibody, Unconjugated (ABIN1386868) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Human Goat Un-conjugated IHC (p), ELISA, WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Bat Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 7 to 9 Days
$463.83
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Rabbit HRP IHC (p), WB   100 μL Log in to see 14 to 21 Days
$405.90
Details

ABCD3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ATP-Binding Cassette, Sub-Family D (Ald), Member 3 Antibodies

  1. Human Polyclonal ABCD3 Primary Antibody for IHC (p), IHC - ABIN451658 : Panov, Kubalik, Zinchenko, Ridings, Radoff, Hemendinger, Brooks, Bonkovsky: Metabolic and functional differences between brain and spinal cord mitochondria underlie different predisposition to pathology. in American journal of physiology. Regulatory, integrative and comparative physiology 2011 (PubMed)
    Show all 2 references for ABIN451658

  2. Human Polyclonal ABCD3 Primary Antibody for ICC, IF - ABIN4346502 : Reams, Jones-Triche, Chan, Hernandez, Soliman, Yates: Immunohistological analysis of ABCD3 expression in Caucasian and African American prostate tumors. in BioMed research international 2015 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family D (Ald), Member 3 Interaction Partners

Mouse (Murine) ATP-Binding Cassette, Sub-Family D (Ald), Member 3 (ABCD3) interaction partners

  1. Abcd3-/- mice accumulated the branched chain fatty acid phytanic acid after phytol loading.

  2. investigation of organelle-targeting properties of N-terminal portions of peroxisomal PMP70; mouse full-length sequence & deletion sequences used as probes for intracellular targeting in COS cells

  3. reduction of PMP70 might underlie decrease in peroxisomal functions and increase in oxidative stress in amyotrophic lateral sclerosis

  4. PPARalpha (show PPARA Antibodies) up-regulates the expression of Abcd3 in small intestine.

Human ATP-Binding Cassette, Sub-Family D (Ald), Member 3 (ABCD3) interaction partners

  1. ABCD1 (show ABCD1 Antibodies) and ABCD2 (show Abcd2 Antibodies) are involved in the transport of long and very long chain fatty acids (VLCFA) or their CoA-derivatives into peroxisomes with different substrate specificities, while ABCD3 is involved in the transport of branched chain acyl-CoA (show GNPAT Antibodies) into peroxisomes.ABCD4 is deduced to take part in the transport of vitamin B12 (show NDUFB3 Antibodies) from lysosomes into the cytosol.

  2. Data show that ACBD3 (show Acbd3 Antibodies) can recruit PI4KB (show PI4KB Antibodies) to model membranes as well as redirect PI4KB (show PI4KB Antibodies) to cellular membranes where it is not naturally found. Also, results show that ACBD3 (show Acbd3 Antibodies) regulates the enzymatic activity of PI4KB (show PI4KB Antibodies) kinase through membrane recruitment rather than allostery.

  3. The N-terminal motif of PMP70 suppresses cotranslational targeting to the endoplasmic reticulum.

  4. Increased ABCD3 expression correlates with Gleason Score.

  5. Deficiency of peroxisomal ABCD3 resulted in bile acid biosynthesis defect.

  6. We postulate a role for human ABCD3 in the oxidation of dicarboxylic acids and a role in buffering fatty acids that are overflowing from the mitochondrial beta-oxidation system

  7. investigation of organelle-targeting properties of N-terminal portions of peroxisomal PMP70; amino acid sequence and domain structure of human form discussed

  8. Pex19p binds to PMP70 co-translationally and keeps PMP70 in a proper conformation for the localization to peroxisome.

  9. Testosterone metabolites did not alter expression of ABCD3 mRNA in fibroblasts from X-linked adrenoleukodystrophy patients.

  10. MP70 (show GJA8 Antibodies) interacts with PEX19 (show PEX19 Antibodies) splice variants PEX19 (show PEX19 Antibodies)-delta-E2 and PEX19p-delta-E8.

ATP-Binding Cassette, Sub-Family D (Ald), Member 3 (ABCD3) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene names and symbols associated with ABCD3

  • ATP-binding cassette, sub-family D (ALD), member 3a (abcd3a) antibody
  • ATP-binding cassette, sub-family D (ALD), member 3 (ABCD3) antibody
  • ATP-binding cassette, sub-family D (ALD), member 3 (abcd3) antibody
  • ATP-binding cassette sub-family D member 3-like (LOC100218710) antibody
  • ATP-binding cassette, sub-family D (ALD), member 3 (LOC100223503) antibody
  • ATP-binding cassette, sub-family D (ALD), member 3 (Abcd3) antibody
  • ATP-binding cassette, subfamily D (ALD), member 3 (Abcd3) antibody
  • ABC43 antibody
  • ABCD3 antibody
  • AI313901 antibody
  • AU018866 antibody
  • AW146054 antibody
  • fb59g09 antibody
  • fd60b04 antibody
  • PMP68 antibody
  • PMP70 antibody
  • PXMP1 antibody
  • wu:fb59g09 antibody
  • wu:fd60b04 antibody
  • zgc:55740 antibody
  • ZWS2 antibody

Protein level used designations for ABCD3

ATP-binding cassette sub-family D member 3 , ATP-binding cassette, sub-family D, member 3 , ATP-binding cassette, sub-family D (ALD), member 3 , ATP-binding cassette, sub-family D, member 3-like , ATP-binding cassette sub-family D member 3-like , 68 kDa peroxisomal membrane protein , 70 kDa peroxisomal membrane protein , peroxisomal membrane protein 1 , peroxisomal membrane protein, 70 kDa , Peroxisomal membrane protein-1 (70kD) , dJ824O18.1 (ATP-binding cassette, sub-family D (ALD), member 3 (PMP70, PXMP1)) , peroxisomal membrane protein 1 (70kD, Zellweger syndrome) , 70-kDa peroxisomal membrane protein , Peroxisomal membrane protein 1

GENE ID SPECIES
406803 Danio rerio
424487 Gallus gallus
432040 Xenopus laevis
457037 Pan troglodytes
479939 Canis lupus familiaris
526059 Bos taurus
100172102 Pongo abelii
100218710 Taeniopygia guttata
100223503 Taeniopygia guttata
100351172 Oryctolagus cuniculus
100406482 Callithrix jacchus
100475140 Ailuropoda melanoleuca
100560970 Anolis carolinensis
100633340 Amphimedon queenslandica
19299 Mus musculus
5825 Homo sapiens
25270 Rattus norvegicus
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