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The protein encoded by ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCG1 Kits (32) and ABCG1 Proteins (9) and many more products for this protein.
Showing 10 out of 99 products:
Chinese Hamster Polyclonal ABCG1 Primary Antibody for ICC, IF - ABIN152900
Hu, Abe-Dohmae, Tsujita, Iwamoto, Ogikubo, Otsuka, Kumon, Yokoyama: Biogenesis of HDL by SAA is dependent on ABCA1 in the liver in vivo. in Journal of lipid research 2008
Show all 99 references for ABIN152900
Human Monoclonal ABCG1 Primary Antibody for ELISA - ABIN394690
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
Show all 5 references for ABIN394690
Human Polyclonal ABCG1 Primary Antibody for IF (p), IHC (p) - ABIN673719
Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. in Molecular medicine reports 2016
Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (show SCARB1 Antibodies) or ABCG1 but not ABCA1 (show ABCA1 Antibodies).
DNA methylation (show HELLS Antibodies) at the ABCG1 locus cg06500161 in blood DNA was associated with an increased risk for future type2 diabetes.
we have newly identified a haplotype-tagging SNP, rs225396, in ABCG1 to be associated with PCV and nAMD in Chinese and Japanese cohorts. This provides new evidence to support ABCG1 as a susceptibility gene for PCV and nAMD.
ABCG1 gene expression positively correlated with obesity indicators.
Our results indicated that genetic variants of ABCG1 may be predictors of survival of nonsmall-cell lung cancer patients
This review focuses on the role of ABC (show ABCB6 Antibodies) transporters A1 and G1 in the pathogenesis of atherosclerosis
Leu at position 550/562 in mABCG1/hABCG1 is critical for their plasma membrane localization but not for ABCG1-mediated cholesterol efflux.
ABCG1 polymorphisms are associated with reduced risk of developing ischemic stroke in hypertriglyceridemic population and atherothrombotic stroke in this cohort of Chinese Han population.
Data suggest that ligand-induced activation of RAGE (advanced glycosylation end product-specific receptor (show AGER Antibodies)) down-regulates ABCG1-mediated cholesterol efflux from macrophages leading to diabetic angiopathies and atherosclerotic plaques.
Propofol up-regulates expression of ABCA1 (show ABCA1 Antibodies), ABCG1, and SR-B1 (show SCARB1 Antibodies) through the PPARgamma (show PPARG Antibodies)/LXRalpha (show NR1H3 Antibodies) pathway in THP-1 (show GLI2 Antibodies) macrophage-derived foam cells.
Expression analysis revealed an association between ABCG1 methylation and lipid levels that might be partly mediated by ABCG1 expression.
ABCG1 may play a protective role in early-stage atherosclerosis by reducing endothelial activation induced by oscillatory shear stress via suppressing the inflammatory response.
Endothelial cholesterol efflux pathways mediated by ABCA1 (show ABCA1 Antibodies) and ABCG1 are nonredundant and atheroprotective, reflecting preservation of endothelial NO synthase (show NOS Antibodies) activity and suppression of endothelial inflammation, especially in regions of disturbed arterial blood flow.
ABCG1, irrespective of either a leucine or proline at position 550, is an intracellular protein (show CKAP2 Antibodies) that localizes to vesicles of the endosomal pathway where it functions to mobilize sterols away from the endoplasmic reticulum and out of the cell.
our study suggests that MEK1 (show MAP2K1 Antibodies)/2 inhibitors activate macrophage ABCG1 expression/RCT (show FOXE3 Antibodies), and inhibit foam cell formation and lesion development by multiple mechanisms, supporting the concept that ERK1/2 (show MAPK1/3 Antibodies) inhibition is anti-atherogenic
miR-33 augments macrophage lipid rafts and enhances proinflammatory cytokine induction and NF-kappaB activation by LPS. This occurs through an ABCA1- and ABCG1-dependent mechanism and is reversible by interventions upon raft cholesterol and by ABC transporter-inducing liver X receptor agonists.
ABCG1 expression was down-regulated by TLR4 (show TLR4 Antibodies), which induces inflammation and lipid accumulation in vascular smooth muscle cells via PPARgamma (show PPARG Antibodies)/LXRalpha (show NR1H3 Antibodies) signaling.
Visfatin (show NAMPT Antibodies) upregulated CD36 (show CD36 Antibodies) and SRA (show MSR1 Antibodies) expression and downregulated ABCA1 (show ABCA1 Antibodies) and ABCG1 expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Antibodies)-dependent pathways.
3beta,5alpha,6beta-cholestanetriol and 25-hydroxycholesterol are physiologic substrates for ABCG1
Our data suggest that GLP-1 (show GCG Antibodies)-based therapy modulate ABCA1 (show ABCA1 Antibodies)/ABCG1 expression in adipocytes potentially through an LXR-alpha (show NR1H3 Antibodies) mediated process.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
ATP-binding cassette sub-family G member 1
, ATP-binding cassette, sub-family G (WHITE), member 1
, ATP-binding cassette sub-family G member 1-like
, ABC transporter 8
, ATP-binding cassette transporter 8
, ATP-binding cassette transporter member 1 of subfamily G
, homolog of Drosophila white
, white protein homolog (ATP-binding cassette transporter 8)
, ATP-binding cassette 8
, ATP-binding cassette, subfamily G, member 1
, white protein homolog