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The protein encoded by ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCG1 Antibodies (100) and ABCG1 Proteins (9) and many more products for this protein.
Showing 10 out of 32 products:
Human ABCG1 ELISA Kit for Sandwich ELISA - ABIN416940
Gluba-Brzózka, Michalska-Kasiczak, Franczyk-Skóra, Nocu?, Banach, Rysz: Markers of increased cardiovascular risk in patients with chronic kidney disease. in Lipids in health and disease 2014
Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (show SCARB1 ELISA Kits) or ABCG1 but not ABCA1 (show ABCA1 ELISA Kits).
Findings suggest that the ABCG1-mediated efflux of cholesterol, but not of 7-ketocholesterol, shows specificity for structural domains of apoA-I (show APOA1 ELISA Kits) bound to reconstituted HDL (show HSD11B1 ELISA Kits). Although the mid region alone of apoA-I (show APOA1 ELISA Kits) associated to rHDL can promote ABCG1-mediated cholesterol efflux, deletion of carboxyl-terminal region 185-243 from full-length apoA-I (show APOA1 ELISA Kits) diminishes ABCG1-mediated cholesterol efflux.
ABCG1 regulates T cell differentiation into Tregs, highlighting a pathway by which cholesterol accumulation can influence T cell homeostasis in atherosclerosis
Data show that ELOVL7 (show ELOVL7 ELISA Kits), SOCS3 (show SOCS3 ELISA Kits), ACSL4 (show ACSL4 ELISA Kits) and CLU (show CLU ELISA Kits) were upregulated while PRKAR1A (show PRKAR1A ELISA Kits) and ABCG1 were downregulated in the phlegm-dampness group.
ABCG1 and ABCG4 (show ABCG4 ELISA Kits) alter the distribution of gamma-secretase on the plasma membrane, leading to the decreased gamma-secretase activity and suppressed Abeta (show APP ELISA Kits) secretion
Both the full-length and the short isoforms of ABCG1 can dimerize with ABCG4 (show ABCG4 ELISA Kits), whereas the ABCG2 (show ABCG2 ELISA Kits) multidrug transporter is unable to form a heterodimer with ABCG4 (show ABCG4 ELISA Kits).
DNA methylation (show HELLS ELISA Kits) at the ABCG1 locus cg06500161 in blood DNA was associated with an increased risk for future type2 diabetes.
we have newly identified a haplotype-tagging SNP, rs225396, in ABCG1 to be associated with PCV and nAMD in Chinese and Japanese cohorts. This provides new evidence to support ABCG1 as a susceptibility gene for PCV and nAMD.
ABCG1 gene expression positively correlated with obesity indicators.
Our results indicated that genetic variants of ABCG1 may be predictors of survival of nonsmall-cell lung cancer patients
This review focuses on the role of ABC (show ABCB6 ELISA Kits) transporters A1 and G1 in the pathogenesis of atherosclerosis
Our data indicate that a combination of vildagliptin and pravastatin significantly induces the expression of LXR (show NR1H3 ELISA Kits)-ABCA1 (show ABCA1 ELISA Kits)/ABCG1 cascade and improves cholesterol efflux (P > 0.05) in adipocytes. Our data may explain, at least in part, the improvement in HDL (show HSD11B1 ELISA Kits)-C levels observed in patients receiving both medications
ABCG1 may play a protective role in early-stage atherosclerosis by reducing endothelial activation induced by oscillatory shear stress via suppressing the inflammatory response.
Endothelial cholesterol efflux pathways mediated by ABCA1 (show ABCA1 ELISA Kits) and ABCG1 are nonredundant and atheroprotective, reflecting preservation of endothelial NO synthase (show NOS ELISA Kits) activity and suppression of endothelial inflammation, especially in regions of disturbed arterial blood flow.
ABCG1, irrespective of either a leucine or proline at position 550, is an intracellular protein (show CKAP2 ELISA Kits) that localizes to vesicles of the endosomal pathway where it functions to mobilize sterols away from the endoplasmic reticulum and out of the cell.
our study suggests that MEK1 (show MAP2K1 ELISA Kits)/2 inhibitors activate macrophage ABCG1 expression/RCT (show FOXE3 ELISA Kits), and inhibit foam cell formation and lesion development by multiple mechanisms, supporting the concept that ERK1/2 (show MAPK1/3 ELISA Kits) inhibition is anti-atherogenic
miR-33 augments macrophage lipid rafts and enhances proinflammatory cytokine induction and NF-kappaB activation by LPS. This occurs through an ABCA1- and ABCG1-dependent mechanism and is reversible by interventions upon raft cholesterol and by ABC transporter-inducing liver X receptor agonists.
ABCG1 expression was down-regulated by TLR4 (show TLR4 ELISA Kits), which induces inflammation and lipid accumulation in vascular smooth muscle cells via PPARgamma (show PPARG ELISA Kits)/LXRalpha (show NR1H3 ELISA Kits) signaling.
Visfatin (show NAMPT ELISA Kits) upregulated CD36 (show CD36 ELISA Kits) and SRA (show MSR1 ELISA Kits) expression and downregulated ABCA1 (show ABCA1 ELISA Kits) and ABCG1 expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 ELISA Kits)-dependent pathways.
Leu at position 550/562 in mABCG1/hABCG1 is critical for their plasma membrane localization but not for ABCG1-mediated cholesterol efflux.
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.
ATP-binding cassette sub-family G member 1
, ATP-binding cassette, sub-family G (WHITE), member 1
, ATP-binding cassette sub-family G member 1-like
, ABC transporter 8
, ATP-binding cassette transporter 8
, ATP-binding cassette transporter member 1 of subfamily G
, homolog of Drosophila white
, white protein homolog (ATP-binding cassette transporter 8)
, ATP-binding cassette 8
, ATP-binding cassette, subfamily G, member 1
, white protein homolog