ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 Proteins (ABCG1)

The protein encoded by ABCG1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCG1 Antibodies (99) and ABCG1 Kits (32) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ABCG1 9619 P45844
ABCG1 11307 Q64343
Rat ABCG1 ABCG1 85264  
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Top ABCG1 Proteins at antibodies-online.com

Showing 6 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 18 Days
$768.00
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HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 11 to 18 Days
$983.13
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ABCG1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)
,

More Proteins for ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) interaction partners

  1. Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (show SCARB1 Proteins) or ABCG1 but not ABCA1 (show ABCA1 Proteins).

Human ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) interaction partners

  1. Data show that ELOVL7, SOCS3 (show SOCS3 Proteins), ACSL4 (show ACSL4 Proteins) and CLU (show CLU Proteins) were upregulated while PRKAR1A (show PRKAR1A Proteins) and ABCG1 were downregulated in the phlegm-dampness group.

  2. ABCG1 and ABCG4 (show ABCG4 Proteins) alter the distribution of gamma-secretase on the plasma membrane, leading to the decreased gamma-secretase activity and suppressed Abeta (show APP Proteins) secretion

  3. Both the full-length and the short isoforms of ABCG1 can dimerize with ABCG4 (show ABCG4 Proteins), whereas the ABCG2 multidrug transporter is unable to form a heterodimer with ABCG4 (show ABCG4 Proteins).

  4. DNA methylation (show HELLS Proteins) at the ABCG1 locus cg06500161 in blood DNA was associated with an increased risk for future type2 diabetes.

  5. we have newly identified a haplotype-tagging SNP, rs225396, in ABCG1 to be associated with PCV and nAMD in Chinese and Japanese cohorts. This provides new evidence to support ABCG1 as a susceptibility gene for PCV and nAMD.

  6. ABCG1 gene expression positively correlated with obesity indicators.

  7. Our results indicated that genetic variants of ABCG1 may be predictors of survival of nonsmall-cell lung cancer patients

  8. This review focuses on the role of ABC (show ABCB6 Proteins) transporters A1 and G1 in the pathogenesis of atherosclerosis

  9. Leu at position 550/562 in mABCG1/hABCG1 is critical for their plasma membrane localization but not for ABCG1-mediated cholesterol efflux.

  10. ABCG1 polymorphisms are associated with reduced risk of developing ischemic stroke in hypertriglyceridemic population and atherothrombotic stroke in this cohort of Chinese Han population.

Mouse (Murine) ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1) interaction partners

  1. Our data indicate that a combination of vildagliptin and pravastatin significantly induces the expression of LXR (show NR1H3 Proteins)-ABCA1 (show ABCA1 Proteins)/ABCG1 cascade and improves cholesterol efflux (P > 0.05) in adipocytes. Our data may explain, at least in part, the improvement in HDL (show HSD11B1 Proteins)-C levels observed in patients receiving both medications

  2. ABCG1 may play a protective role in early-stage atherosclerosis by reducing endothelial activation induced by oscillatory shear stress via suppressing the inflammatory response.

  3. Endothelial cholesterol efflux pathways mediated by ABCA1 and ABCG1 are nonredundant and atheroprotective, reflecting preservation of endothelial NO synthase activity and suppression of endothelial inflammation, especially in regions of disturbed arterial blood flow.

  4. ABCG1, irrespective of either a leucine or proline at position 550, is an intracellular protein (show CKAP2 Proteins) that localizes to vesicles of the endosomal pathway where it functions to mobilize sterols away from the endoplasmic reticulum and out of the cell.

  5. our study suggests that MEK1/2 inhibitors activate macrophage ABCG1 expression/RCT, and inhibit foam cell formation and lesion development by multiple mechanisms, supporting the concept that ERK1/2 inhibition is anti-atherogenic

  6. miR-33 augments macrophage lipid rafts and enhances proinflammatory cytokine induction and NF-kappaB activation by LPS. This occurs through an ABCA1- and ABCG1-dependent mechanism and is reversible by interventions upon raft cholesterol and by ABC transporter-inducing liver X receptor agonists.

  7. ABCG1 expression was down-regulated by TLR4 (show TLR4 Proteins), which induces inflammation and lipid accumulation in vascular smooth muscle cells via PPARgamma (show PPARG Proteins)/LXRalpha (show NR1H3 Proteins) signaling.

  8. Visfatin (show NAMPT Proteins) upregulated CD36 (show CD36 Proteins) and SRA (show MSR1 Proteins) expression and downregulated ABCA1 (show ABCA1 Proteins) and ABCG1 expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Proteins)-dependent pathways.

  9. Leu at position 550/562 in mABCG1/hABCG1 is critical for their plasma membrane localization but not for ABCG1-mediated cholesterol efflux.

  10. 3beta,5alpha,6beta-cholestanetriol and 25-hydroxycholesterol are physiologic substrates for ABCG1

ABCG1 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Six alternative splice variants have been identified.

Gene names and symbols associated with ABCG1

  • ATP-binding cassette, sub-family G (WHITE), member 1 (ABCG1)
  • ATP-binding cassette, sub-family G (WHITE), member 1 (abcg1)
  • ATP-binding cassette, sub-family G (WHITE), member 1 (Abcg1)
  • ATP-binding cassette, subfamily G (WHITE), member 1 (Abcg1)
  • Abc8 protein
  • ABCG1 protein
  • AW413978 protein
  • White protein
  • WHITE1 protein
  • zgc:162197 protein

Protein level used designations for ABCG1

ATP-binding cassette sub-family G member 1 , ATP-binding cassette, sub-family G (WHITE), member 1 , ATP-binding cassette sub-family G member 1-like , ABC transporter 8 , ATP-binding cassette transporter 8 , ATP-binding cassette transporter member 1 of subfamily G , homolog of Drosophila white , white protein homolog (ATP-binding cassette transporter 8) , ATP-binding cassette 8 , ATP-binding cassette, subfamily G, member 1 , white protein homolog

GENE ID SPECIES
418533 Gallus gallus
458577 Pan troglodytes
487777 Canis lupus familiaris
510745 Bos taurus
556979 Danio rerio
100014129 Monodelphis domestica
100058103 Equus caballus
100077803 Ornithorhynchus anatinus
100470191 Ailuropoda melanoleuca
9619 Homo sapiens
11307 Mus musculus
85264 Rattus norvegicus
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