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ATPase, Ca++ Transporting, Plasma Membrane 1 Proteins (ATP2B1)

The protein encoded by ATP2B1 belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. Additionally we are shipping ATP2B1 Antibodies (20) and ATP2B1 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATP2B1 490 P20020
Rat ATP2B1 ATP2B1 29598 P11505
ATP2B1 67972  
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Top ATP2B1 Proteins at antibodies-online.com

Showing 5 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ATP2B1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1) Interaction Partners

Cow (Bovine) ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1) interaction partners

  1. Adding pure bovine MMP-2 (show MMP2 Proteins) to the smooth muscle membrane suspension causes an increase in Ca(2+)-ATPase activity, but the pretreatment with TIMP-2 (show TIMP2 Proteins) inhibits the increase in the enzyme activity

  2. To demonstrate the subcellular localization and regulation of bovine sperm PMCA, cell fractionation, enzyme activity determination and Western blotting studies of PMCA in spermatozoa removed from the cauda epididymidis of bull, was performed.

Human ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1) interaction partners

  1. Data show that plasma membrane Ca(2+)-ATPase (show ATP2B2 Proteins) (PMCA) was associated with tubulin (show TUBB Proteins) in normotensive and hypertensive erythrocytes.

  2. rs11105378 near ATP2B1 was associated with increased systolic and diastolic blood pressure in a Chinese population.

  3. ATP2B1 rs12817819 A allele is associated with increased risk for drug resistant hypertension.

  4. While PMCA1b has a housekeeping function in colon cancer cells, PMCA4b (show ATP2B4 Proteins) participates in the reorganization of the calcium signaling machinery during cell differentiation.

  5. Report that ATP2B1 rs2681472 is associated with early-onset preeclampsia in Northern Han Chinese women.

  6. An increase of phosphatidylcholine (show SGMS2 Proteins)/detergent molar ratio leads to a biphasic behavior of the PMCA Ca2+-ATPase activity, whose maximum depends on phosphatidylcholine (show SGMS2 Proteins) characteristics.

  7. The present study confirmed the significant association of ATP2B1 rs17249754 with risk of hypertension among Chinese children.

  8. The downregulation of PMCA1 and the disruption of calcium homeostasis may play important roles in UVB-induced HLE (show ELANE Proteins) B-3 cell apoptosis.

  9. analysis of how human plasma membrane Ca2 (show CA2 Proteins)+ pump PMCA h4xb is hyperactivated by mutation of Glu99 to Lys (show LYZ Proteins)

  10. Association of the ATP2B1 gene and susceptibility to hypertension, blood pressure traits and carotid-femoral pulse wave velocities in a Chinese population.

Pig (Porcine) ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1) interaction partners

  1. Purified plasma membrane Ca2+ ATPase was able to hydrolyze ATP at a very low rate in the absence of Ca2 (show CA2 Proteins)+.

  2. results suggest that the activating mechanism of ethanol may involve opening an autoinhibitory domain located close to the calmodulin (show CALM Proteins) binding domain

  3. ceramide activates plasma membrane Ca2+-ATPase from kidney-promixal tubule cells with protein kinase A as an intermediate

Mouse (Murine) ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1) interaction partners

  1. Deletion of the Pmca1 in the intestine is associated with reduced growth and bone mineralization, and a failure to up-regulate calcium absorption in response to 1alpha,25(OH)2D3.

  2. decreased ATP2B1 gene expression is associated with impaired endothelial NOS (show NOS3 Proteins) activity and nitric oxide production, and the ATP2B1 gene plays a crucial role in the regulation of blood pressure

  3. ATP2B1 is the causative gene in the blood pressure-associated 12q21 locus; ATP2B1 expression in the vessel influences blood pressure

  4. ATP2B1 plays important roles in the regulation of blood pressure through alteration of calcium handling and vasoconstriction in vascular smooth muscle cells.

  5. Cav1.4alpha1 (show CACNA1F Proteins) is required for proper targeting of the presynaptic PMCA1 complex in retinal photoreceptors.

  6. the decapacitation mechanism of the SVA might target membrane sphingolipid SPM (show NPC1 Proteins) and regulate PMCA activity to lower [Ca(2 (show CA2 Proteins)+)](i), thereby decreasing the [cAMP](i) level and preventing sperm pre-capacitation.

  7. Plasma membrane Ca2+-ATPase and NCX1 Na+/Ca2+ exchanger (show SLC8A1 Proteins) expression in distal convoluted tubule cells mediate calcium efflux.

  8. Mouse photoreceptors, cone bipolar cells and horizontal cells, which respond to light with a graded polarization, express isoform PMCA1

  9. results are consistent with an essential housekeeping or developmental function for plasma membrane Ca2+-ATPase (PMCA)1

  10. Data indicate that plasma membrane Ca(2 (show CA2 Proteins)+)-ATPases 1 and 4, in addition to SERCA2 (show ATP2A2 Proteins) and NCX (show SLC8A1 Proteins), play a significant role in both excitation-contraction coupling and calcium homeostasis in bladder smooth muscle.

ATP2B1 Protein Profile

Protein Summary

The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with ATP2B1

  • ATPase, Ca++ transporting, plasma membrane 1 (ATP2B1)
  • ATPase, Ca++ transporting, plasma membrane 1 (atp2b1)
  • ATPase, Ca++ transporting, plasma membrane 1 (Atp2b1)
  • 2810442I22Rik protein
  • ATP2B1 protein
  • DKFZp459A1127 protein
  • E130111D10Rik protein
  • PMCA protein
  • Pmca1 protein
  • Pmca1a protein
  • Pmca1b protein
  • Pmca1c protein
  • PMCA1kb protein

Protein level used designations for ATP2B1

plasma membrane calcium ATPase 1 , plasma membrane calcium-transporting ATPase 1 , plasma membrane calcium pump , ATPase, Ca++ transporting, plasma membrane 1 , plasma membrane calcium-transporting ATPase 1-like , PMCA1 , plasma membrane calcium ATPase , plasma membrane Ca2+ pump (PMCA1b) , Ca2+/Mg2+ ATPase

GENE ID SPECIES
282641 Bos taurus
403480 Canis lupus familiaris
549593 Xenopus (Silurana) tropicalis
100051636 Equus caballus
100172812 Pongo abelii
100011221 Monodelphis domestica
100407701 Callithrix jacchus
100127567 Xenopus (Silurana) tropicalis
100180580 Ciona intestinalis
100591048 Nomascus leucogenys
490 Homo sapiens
29598 Rattus norvegicus
397636 Sus scrofa
67972 Mus musculus
374244 Gallus gallus
100009543 Oryctolagus cuniculus
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