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ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D2 Proteins (ATP6V0D2)

Subunit of the integral membrane V0 complex of vacuolar ATPase. Additionally we are shipping ATP6V0D2 Antibodies (13) and ATP6V0D2 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATP6V0D2 245972 Q8N8Y2
Mouse ATP6V0D2 ATP6V0D2 242341 Q80SY3
ATP6V0D2 297932 Q5FVL0
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Top ATP6V0D2 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,951.67
Details
Yeast Pongo abelii His tag   1 mg Log in to see 56 to 66 Days
$2,951.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,951.67
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,955.33
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ATP6V0D2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

More Proteins for ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D2 (ATP6V0D2) Interaction Partners

Human ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D2 (ATP6V0D2) interaction partners

  1. these data suggest that Adrm1 (show Adrm1 Proteins), a new Atp6v0d2-interacting protein, plays an important role in osteoclast differentiation, and in particular the fusion of preosteoclasts.

Mouse (Murine) ATPase, H+ Transporting, Lysosomal 38kDa, V0 Subunit D2 (ATP6V0D2) interaction partners

  1. we propose that PTH (show PTH Proteins) has a direct effect on osteoblasts and osteoclasts, and that this effect is mediated through PTH1R (show PTH1R Proteins), thus contributing to bone remodeling

  2. Insulin (show INS Proteins) significantly activated ERK1/2 MAP kinase (show MAPK1 Proteins) as well as markedly induced the expression of NFATc1 (show NFATC1 Proteins), an osteoclast marker gene, and Atp6v0d2, an osteoclast fusion-related gene.

  3. V-ATPase (show ATP6V1H Proteins) has a role in modulating a macrophage phenotype towards tumor-associated macrophages through the action of the a2 isoform of V-ATPase (show ATP6V1H Proteins)

  4. Luteolin can be effective in reducing bone resorption and that this effect of luteolin may be through disruption of osteoclast V-ATPase a3 (show TCIRG1 Proteins)-d2 interaction.

  5. PKCdelta deficiency does not perturb formation of the ruffled border or trafficking of lysosomal vesicles containing the vacuolar-ATPase (v-ATPase).

  6. these findings suggest that the critical role of ATP6v0d2 may be limited to the control of bone homeostasis under normal development.

  7. The data indicate that integrity of lipid rafts regulates the activity of V-ATPase (show ATP6V1H Proteins) in osteoclasts, suggesting that cholesterol-lowering agents might be useful for inhibiting osteoclast-dependent bone resorption.

  8. Atp6v0d2 is a regulator of osteoclast fusion and bone formation.

  9. Data indicate for the first time that the NFATc1/Atp6v0d2 and DC-STAMP signaling axis plays a key role in the osteoclast multinucleation process, which is essential for efficient bone resorption.

  10. Atp6v0d2 (d2), an isoform of the d subunit in the V-ATPase (show ATP6V1H Proteins), showed 5-fold higher expression than that of Atp6v0d1 (show ATP6V0D1 Proteins) (d1) in mature osteoclasts, indicating a potential function in osteoclastic bone resorption.

ATP6V0D2 Protein Profile

Protein Summary

Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity). May play a role in coupling of proton transport and ATP hydrolysis. Regulator of osteoclast fusion and bone formation.

Gene names and symbols associated with ATP6V0D2

  • ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (atp6v0d2)
  • ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2 (ATP6V0D2)
  • ATPase, H+ transporting, lysosomal V0 subunit D2 (Atp6v0d2)
  • 1620401A02Rik protein
  • AI324824 protein
  • ATP6D2 protein
  • V-ATPase protein
  • VMA6 protein

Protein level used designations for ATP6V0D2

ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d , V-ATPase subunit d 2 , V-type proton ATPase subunit d 2 , vacuolar proton pump subunit d 2 , Vacuolar proton pump subunit d 2 , ATPase, H+ transporting, V0 subunit D , osteoclast-specific vacuolar ATP synthase , vacuolar proton-translocating ATPase d subunit d2 , ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2

GENE ID SPECIES
447489 Xenopus laevis
420210 Gallus gallus
245972 Homo sapiens
477929 Canis lupus familiaris
511839 Bos taurus
100173359 Pongo abelii
242341 Mus musculus
297932 Rattus norvegicus
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