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ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 Proteins (ATP6V1B2)

ATP6V1B2 encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Additionally we are shipping ATP6V1B2 Antibodies (52) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATP6V1B2 117596 P62815
ATP6V1B2 526 P21281
Mouse ATP6V1B2 ATP6V1B2 11966 P62814
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Top ATP6V1B2 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,452.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ATP6V1B2 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human , ,
,

More Proteins for ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2) Interaction Partners

Human ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2) interaction partners

  1. A missense mutation in ATP6V1B2 associated with Zimmermann-Laband syndrome.

  2. The ATP6V1B2 p.Arg506X is a haploinsufficient mutation and resulted in abnormal acidification in lysosomes.

Zebrafish ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2) interaction partners

  1. vatB1 and vatB2 are differentially expressed in embryos.

Mouse (Murine) ATPase, H+ Transporting, Lysosomal 56/58kDa, V1 Subunit B2 (ATP6V1B2) interaction partners

  1. ATP6V1B2 is a molecular target of SIRT1 (show SIRT1 Proteins) in fat cells.

  2. Disruption of vacuolar H+-ATPase a3-B2 subunit interaction inhibited osteoclast bone resorption.

  3. Redistribution of Atp6v1b2 occurs from intracellular compartments into the apical membrane of epididymal clear cells from Atp6v1b1 (show ATP6V1B1 Proteins)(-/-) mice.

  4. the activity of apical B2-containing V-ATPase (show ATP6V1H Proteins) holoenzymes in A intercalated cells is sufficient to maintain baseline acid-base homeostasis

ATP6V1B2 Protein Profile

Protein Summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A, three B, and two G subunits, as well as a C, D, E, F, and H subunit. The V1 domain contains the ATP catalytic site. The protein encoded by this gene is one of two V1 domain B subunit isoforms and is the only B isoform highly expressed in osteoclasts.

Gene names and symbols associated with ATP6V1B2

  • ATPase, H transporting, lysosomal V1 subunit B2 (Atp6v1b2)
  • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (atp6v1b2)
  • ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 (ATP6V1B2)
  • ATPase, H+ transporting, lysosomal V1 subunit B2 (atp6v1b2)
  • ATPase, H+ transporting, lysosomal V1 subunit B2 (Atp6v1b2)
  • AI194269 protein
  • AI790362 protein
  • ATP6B1B2 protein
  • ATP6B2 protein
  • atp6v1bb protein
  • fj51e01 protein
  • HO57 protein
  • R74844 protein
  • VATB protein
  • vatB2 protein
  • vha55 protein
  • Vma2 protein
  • VPP3 protein
  • wu:fj51e01 protein
  • zgc:109771 protein

Protein level used designations for ATP6V1B2

ATPase, H+ transporting, V1 subunit B , ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa , V-ATPase subunit B 2 , V-type proton ATPase subunit B, brain isoform , endomembrane proton pump 58 kDa subunit , vacuolar H+ATPase B2 , vacuolar proton pump subunit B 2 , ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B , vacuolar H-ATPase B subunit osteoclast isozyme , H+ transporting two-sector ATPase , V-ATPase B2 subunit , vacuolar H+-ATPase 56,000 subunit , H+-ATPase B subunit , H+-ATPase non-catalytic subunit B , vacuolar H+-ATPase , Vacuolar ATP synthase subunit B, brain isoform , ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 , ATPase, H+ transporting, lysosomal, V1 subunit B, member b , ATPase, H+ transporting, lysosomal 56/58kD, V1 subunit B , lysosomal 56/58kDa

GENE ID SPECIES
117596 Rattus norvegicus
380305 Xenopus laevis
395497 Gallus gallus
526 Homo sapiens
486137 Canis lupus familiaris
338082 Bos taurus
100173673 Pongo abelii
359840 Danio rerio
11966 Mus musculus
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