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A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. Additionally we are shipping ATAD2 Kits (4) and ATAD2 Proteins (4) and many more products for this protein.
Showing 10 out of 47 products:
Human Polyclonal ATAD2 Primary Antibody for EIA, WB - ABIN950545
Revenko, Kalashnikova, Gemo, Zou, Chen: Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. in Molecular and cellular biology 2010
Show all 5 references for ABIN950545
Human Polyclonal ATAD2 Primary Antibody for WB - ABIN656997
Zou, Guo, Revenko, Tepper, Gemo, Kung, Chen: Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer. in Cancer research 2009
Show all 3 references for ABIN656997
Human Polyclonal ATAD2 Primary Antibody for ICC, IF - ABIN4281939
Raeder, Birkeland, Trovik, Krakstad, Shehata, Schumacher, Zack, Krohn, Werner, Moody, Wik, Stefansson, Holst, Oyan, Tamayo, Mesirov, Kalland, Akslen, Simon, Beroukhim, Salvesen: Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. in PLoS ONE 2013
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Suppression of ATAD2 impaired the growth of HepG2 and Hep3B subcutaneous xenografts, by enhancing apoptosis and p-p53 (show TP53 Antibodies) and p-p38 (show CRK Antibodies) levels.
Data indicate that gene expression alterations in endometrial carcinoma samples with high ATPase (show DNAH8 Antibodies) family, AAA (show APP Antibodies) domain containing 2 protein (ATAD2) expression showed upregulation of several cancer-related genes including B-MYB (show MYBL2 Antibodies) gene.
Results showed that ATPase family AAA domain-containing 2 overexpression was associated with progression and prognosis of colorectal cancer.
Cervical cancer tissues may have highly expressed ATAD2. Oncogene (show RAB1A Antibodies) ATAD2 may play an important role in cervical cancer proliferation, invasion and migration.
We identified ANCCA protein expression as a novel independent poor prognostic indicator in endometrial carcinoma
Study reveals ANCCA as a key mediator of kinesin family deregulation in breast cancer and the crucial role of multiple kinesins in growth and survival of the tumor cells.
Results found that ATAD2 is highly expressed in hepatocellular carcinoma tissues and could affect the expression of hedghog pathway.
High expression of ATAD2 is associated with ovarian carcinomas
miR (show MLXIP Antibodies)-372 suppressed the expression of ATAD2, which was highly expressed in HCC (show FAM126A Antibodies) and exerted a proto-oncogene (show RAB1A Antibodies) effect in hepatic carcinogenesis.
High ANCCA protein expression is associated with lymphatic metastasis in lung adenocarcinoma.
EZH2 (show EZH2 Antibodies) and ANCCA are androgen regulated and strongly expressed in early prostate morphogenesis and during puberty, suggesting their important role in prostate development.
A large family of ATPases has been described, whose key feature is that they share a conserved region of about 220 amino acids that contains an ATP-binding site. The proteins that belong to this family either contain one or two AAA (ATPases Associated with diverse cellular Activities) domains. AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes. The protein encoded by this gene contains two AAA domains, as well as a bromodomain.
ATPase family AAA domain-containing protein 2
, AAA nuclear coregulator cancer-associated protein