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ATPase Type 13A2 Proteins (ATP13A2)

ATP13A2 encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Additionally we are shipping ATP13A2 Antibodies (50) and ATP13A2 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ATP13A2 ATP13A2 362645  
ATP13A2 23400 Q9NQ11
ATP13A2 74772 Q9CTG6
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Top ATP13A2 Proteins at antibodies-online.com

Showing 5 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 69 to 74 Days
$12,906.52
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 69 to 74 Days
$9,050.32
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

ATP13A2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
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More Proteins for ATPase Type 13A2 (ATP13A2) Interaction Partners

Zebrafish ATPase Type 13A2 (ATP13A2) interaction partners

  1. Thsi stduy Our findings bring new insight into the biology of ATP13A2 and open novel opportunities for its study using zebrafish as a model organism.

Human ATPase Type 13A2 (ATP13A2) interaction partners

  1. tre (show TREH Proteins) results of this study suggests that the expression of ATP13A2 regulated by the PHD2 (show EGLN1 Proteins)-HIF1alpha (show HIF1A Proteins) signaling pathway,and this is instrumental in maintaining cellular iron homeostasis and cell viability in mitochondrially compromised DAergic neurons.

  2. that ATP13A2 contains a unique N-terminal hydrophobic extension that lies on the cytosolic membrane surface of the lysosome, where it interacts with the lysosomal signaling lipids phosphatidic acid and phosphatidylinositol(3,5)bisphosphate.

  3. ATP13A2 overexpression improves the lysosome membrane integrity and protects against iron-induced cell damage.

  4. A review of recent advances in the emerging association of ATP13A2 mutations with Parkinsonism and neuronal ceroid lipofuscinoses.

  5. The mutation rates of Thr12Met and Ala1144Thr of ATP13A2 in the Uygur and Han Parkinson's disease patients in the Xinjiang region are low.

  6. This study demonistrated that loss of ATP13A2 causes a specific protein trafficking defect, and that Atp13a2 null mice develop age-related motor dysfunction that is preceded by neuropathological changes.

  7. Data show that patients with Lewy body diseases have an overall deficit in ATP13A2 protein levels, with the remaining protein being more insoluble and partially redistributing towards Lewy bodies

  8. Present results of homozygosity mapping in two siblings affected with early onset Parkinson's disease (EOPD) and mutation screening of ATP13A2. The variation identified represents the 13th known disease causing mutation in ATP13A2.

  9. these data suggest the involvement of PARK9 in the biogenesis of exosomes and alpha-synuclein secretion.

  10. Reduced ATP13A2 expression significantly decreased vesicular zinc levels, indicating ATP13A2 facilitates transport of zinc.

Mouse (Murine) ATPase Type 13A2 (ATP13A2) interaction partners

  1. the loss of Atp13a2 causes sensorimotor impairments, alpha-synuclein accumulation as occurs in PD and related synucleinopathies, and accumulation of lipofuscin deposits characteristic of NCL (show NCL Proteins)

  2. study reveals a number of intriguing neuronal phenotypes due to the loss- or gain-of-function of ATP13A2 that support a role for this protein in regulating intracellular cation homeostasis and neuronal integrity

  3. This study showed that ATP13A2 regulates mitochondrial bioenergetics through macroautophagy.

ATP13A2 Protein Profile

Protein Summary

This gene encodes a member of the P5 subfamily of ATPases which transports inorganic cations as well as other substrates. Mutations in this gene are associated with Kufor-Rakeb syndrome (KRS), also referred to as Parkinson disease 9. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ATPase Type 13A2 Proteins (ATP13A2)

  • ATPase type 13A2 (Atp13a2)
  • ATPase type 13A2 (ATP13A2)
  • ATPase type 13A2 (atp13a2)
  • ATPase type 13A2 (PTRG_01071)
  • ATPase type 13A2 (MCYG_01937)
  • ATPase type 13A2 (LOC100222246)
  • ATPase type 13A2 (LOC100344893)
  • ATPase type 13A2 (LOC100358965)
  • ATPase type 13A2 (PGTG_17045)
  • 1110012E06Rik protein
  • AA589443 protein
  • ATP13A2 protein
  • CLN12 protein
  • HSA9947 protein
  • im:7147302 protein
  • KRPPD protein
  • PARK9 protein
  • RGD1307977 protein
  • zgc:136762 protein

Protein level used designations for ATPase Type 13A2 Proteins (ATP13A2)

probable cation-transporting ATPase 13A2 , ATPase type 13A2 , N-ATPase , probable cation-transporting ATPase 13A2-like , putative ATPase

GENE ID SPECIES
362645 Rattus norvegicus
419466 Gallus gallus
456525 Pan troglodytes
510792 Bos taurus
568666 Danio rerio
699678 Macaca mulatta
100053155 Equus caballus
6338252 Pyrenophora tritici-repentis Pt-1C-BFP
9229055 Arthroderma otae CBS 113480
100026165 Monodelphis domestica
100222246 Taeniopygia guttata
100344893 Oryctolagus cuniculus
100358965 Oryctolagus cuniculus
100439053 Pongo abelii
100523971 Sus scrofa
10530751 Puccinia graminis f. sp. tritici CRL 75-36-700-3
23400 Homo sapiens
74772 Mus musculus
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