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anti-ATX1 Antioxidant Protein 1 Homolog (Yeast) (ATOX1) Antibodies

ATOX1 encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. Additionally we are shipping ATOX1 Proteins (16) and ATOX1 Kits (1) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATOX1 475 O00244
ATOX1 84355 Q9WUC4
ATOX1 11927 O08997
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Top anti-ATOX1 Antibodies at antibodies-online.com

Showing 10 out of 28 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to ATOX1 on HeLa cell (antibody concentration 10 µg/mL). ATOX1 monoclonal antibody (M01), clone 2E6 Western Blot analysis of ATOX1 expression in HeLa NE. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated WB ATOX1 monoclonal antibody (M08), clone 4D6. Western Blot analysis of ATOX1 expression in human spleen. ATOX1 monoclonal antibody (M08), clone 4D6. Western Blot analysis of ATOX1 expression in COLO 320 HSR. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ICC, IF, WB 0.025 mL Log in to see 5 to 7 Days
$140.44
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (33.22 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, ELISA, WB ATOX1 monoclonal antibody (M01), clone 2E6 Western Blot analysis of ATOX1 expression in Hela S3 NE . Immunofluorescence of monoclonal antibody to ATOX1 on HeLa cell. [antibody concentration 10 ug/ml] 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated IF, ELISA, WB   100 μg Log in to see 8 to 10 Days
$537.17
Details
Human Rabbit Un-conjugated IF   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry of Human lung cancer using ATOX1 Polyclonal Antibody at dilution of 1:30 200 μL Log in to see 8 to 9 Days
$588.50
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 14 Days
$369.79
Details
Human Mouse Un-conjugated IF, ELISA, WB   100 μg Log in to see 11 to 16 Days
$553.14
Details

ATOX1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
,
,
Rat (Rattus)


Mouse (Murine)


Top referenced anti-ATOX1 Antibodies

  1. Human Monoclonal ATOX1 Primary Antibody for IF, WB - ABIN394577 : Banci, Bertini, Calderone, Della-Malva, Felli, Neri, Pavelkova, Rosato: Copper(I)-mediated protein-protein interactions result from suboptimal interaction surfaces. in The Biochemical journal 2009 (PubMed)
    Show all 5 references for ABIN394577

  2. Human Monoclonal ATOX1 Primary Antibody for WB - ABIN396339 : Rodriguez-Granillo, Wittung-Stafshede: Differential roles of Met10, Thr11, and Lys60 in structural dynamics of human copper chaperone Atox1. in Biochemistry 2009 (PubMed)
    Show all 5 references for ABIN396339

More Antibodies against ATOX1 Interaction Partners

Fruit Fly (Drosophila melanogaster) ATX1 Antioxidant Protein 1 Homolog (Yeast) (ATOX1) interaction partners

  1. results clearly reveal a distorted copper homeostasis in Atox1-deficient Drosophila

Human ATX1 Antioxidant Protein 1 Homolog (Yeast) (ATOX1) interaction partners

  1. In addition to Atox1, the human cytoplasm also contains Cu chaperones for loading of superoxide dismutase 1 (show SOD1 Antibodies) (i.e. CCS (show CCS Antibodies)) and cytochrome c (show CYCS Antibodies) oxidase in mitochondria (i.e. Cox17 (show COX17 Antibodies)). [review]

  2. results suggest the possibility of a therapy with copper-chelating or ionophore drugs in subtypes of tumors showing specific alterations in ATOX1 expression

  3. C-Terminus of Human Copper Importer Ctr1 (show SLC31A1 Antibodies) Acts as a Binding Site and Transfers Copper to Atox1

  4. Cu chaperone function of Atox1 mediated through Cu transporter ATP7A (show ATP7A Antibodies) is required for VEGF (show VEGFA Antibodies)-induced angiogenesis via activation of Cu enzyme lysyl oxidase (show LOX Antibodies).

  5. Upon neuronal differentiation, transitions in redox states upregulates expression of ATOX1 and its partner ATP7A (show ATP7A Antibodies), producing higher flux of copper through the secretory pathway.

  6. To identify new interactions partners of Atox1, a yeast two-hybrid screen with a large human placenta library of cDNA fragments using Atox1 as bait, was performed.

  7. Studied the localization of Atox1 in HeLa cells using fluorescence imaging in combination with in vitro binding experiments to fluorescently labeled DNA duplexes harboring the proposed promotor sequence.

  8. Human cytoplasmic copper chaperones Atox1 and CCS (show CCS Antibodies) exchange copper ions in vitro

  9. Cisplatin is one of the most used anticancer drugs. Its cellular influx and delivery to target DNA may involve the copper chaperone Atox1 protein.

  10. The data collected here shows that the Atox1 keeps its dimer nature also in the presence of the CTR1 (show SLC31A1 Antibodies) c-terminal domain; however, two geometrical states are assumed by the Atox1.

Mouse (Murine) ATX1 Antioxidant Protein 1 Homolog (Yeast) (ATOX1) interaction partners

  1. Cu chaperone function of Atox1 mediated through Cu transporter ATP7A (show ATP7A Antibodies) is required for VEGF (show VEGFA Antibodies)-induced angiogenesis via activation of Cu enzyme lysyl oxidase (show LOX Antibodies).

  2. Atox1 is involved in neointimal formation after vascular injury through promoting vascular smooth muscle cell migration and inflammatory cell recruitment in injured vessels

  3. Atox1 functions to prevent Ang II (show AGT Antibodies)-induced endothelial dysfunction and hypercontraction in resistant vessels, as well as hypertension.

  4. the importance of Atox1, not only as a metallochaperone for delivering Cu to cuproenzymes, but also as a key player in maintaining the proper distribution and organization of Cu at the cellular level

  5. ATOX1 is a cytoplasmic copper chaperone that interacts with the copper-binding domain of the membrane copper transporters ATP7A (show ATP7A Antibodies) and ATP7B (show ATP7B Antibodies)

  6. Atox1 has a role in establishing the threshold for copper-dependent movement of the copper-transporting ATPases within the secretory compartment

  7. Atox1 functions not only as a copper chaperone for SOD3 (show SOD3 Antibodies) but also as a positive regulator for SOD3 (show SOD3 Antibodies) transcription and may have an important role in modulating oxidative stress in the cardiovascular system.

  8. Atox1 functions as a novel transcription factor that, when activated by copper, undergoes nuclear translocation, DNA binding, and transactivation, thereby contributing to cell proliferation.

  9. both the copper chaperone and the transcription factor functions are required for the activity of antioxidant enzyme, superoxide dismutase (SOD3 (show SOD3 Antibodies))

  10. Atox1 is required for the polyubiquitination of Ctr1 (show SLC31A1 Antibodies) and the Ctr1 (show SLC31A1 Antibodies)-mediated uptake of CDDP.

ATOX1 Antigen Profile

Protein Summary

This gene encodes a copper chaperone that plays a role in copper homeostasis by binding and transporting cytosolic copper to ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. This protein also functions as an antioxidant against superoxide and hydrogen peroxide, and therefore, may play a significant role in cancer carcinogenesis. Because of its cytogenetic location, this gene represents a candidate gene for 5q-syndrome.

Gene names and symbols associated with ATOX1

  • ATX1 antioxidant protein 1 homolog (yeast) (ATOX1) antibody
  • CG32446 gene product from transcript CG32446-RA (Atox1) antibody
  • ATX1 antioxidant protein 1 homolog (atox1) antibody
  • copper transport protein (atox1) antibody
  • Copper transport protein ATOX1 (atox1) antibody
  • ATX1 antioxidant protein 1 homolog (LOC100335457) antibody
  • antioxidant 1 copper chaperone (ATOX1) antibody
  • antioxidant 1 copper chaperone (Atox1) antibody
  • ATX1 (antioxidant protein 1) homolog 1 (yeast) (Atox1) antibody
  • AI256639 antibody
  • ATOX1 antibody
  • Atx1 antibody
  • CG12562 antibody
  • CG32446 antibody
  • DDBDRAFT_0185901 antibody
  • DDBDRAFT_0266724 antibody
  • DDB_0185901 antibody
  • DDB_0266724 antibody
  • DmAtox1 antibody
  • Dmel\\CG32446 antibody
  • HAH1 antibody
  • SAH antibody

Protein level used designations for ATOX1

ATX1 antioxidant protein 1 homolog (yeast) , copper transport protein ATOX1 , antioxidant protein 1 homolog , Atox1-PA , Atox1-PB , CG32446-PA , CG32446-PB , ATX1 antioxidant protein 1 homolog , Copper transport protein ATOX1 , metal transport protein ATX1 , ATX1 (antioxidant protein 1) homolog 1 , ATX1 homolog protein Rah1 , copper chaperone , copper chaperone SAH

GENE ID SPECIES
743743 Pan troglodytes
770231 Gallus gallus
100312962 Sus scrofa
326216 Drosophila melanogaster
734100 Xenopus (Silurana) tropicalis
8624483 Dictyostelium discoideum AX4
100301872 Oncorhynchus mykiss
100335457 Bos taurus
475 Homo sapiens
84355 Rattus norvegicus
11927 Mus musculus
613998 Bos taurus
403713 Canis lupus familiaris
443451 Ovis aries
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