You are viewing an incomplete version of our website. Please click to reload the website as full version.

AarF Domain Containing Kinase 3 Proteins (ADCK3)

ADCK3 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. Additionally we are shipping ADCK3 Antibodies (99) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADCK3 56997 Q8NI60
ADCK3 67426 Q60936
Rat ADCK3 ADCK3 360887 Q5BJQ0
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ADCK3 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details

ADCK3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for AarF Domain Containing Kinase 3 (ADCK3) Interaction Partners

Human AarF Domain Containing Kinase 3 (ADCK3) interaction partners

  1. ADCK3/COQ8 localises to mitochondrial cristae and is targeted to this organelle via the presence of an N-terminal localisation signal

  2. work reveals Mg(2 (show MUC7 Proteins)+)-dependent ATPase activity of ADCK3, providing strong support for the theoretical prediction of this protein being a functional atypical kinase.

  3. a structural foundation for investigating the role of transmembrane association in regulating the biological activity of ADCK3

  4. Mitochondrial ADCK3 employs an atypical protein kinase-like fold to enable coenzyme Q biosynthesis.

  5. These observations highlight the importance of screening for a potentially treatable cause, CABC1/ADCK3 mutations

  6. play an important role in mediating p53 (show TP53 Proteins)-inducible apoptosis through the mitochondrial pathway.

  7. CABC1 gene mutations in four ubiquinone-deficient patients in three distinct families were reported.

  8. Five additional mutations in ADCK3 were found in three patients with sporadic ataxia (show USP14 Proteins), including one known to have CoQ10 deficiency in muscle.

ADCK3 Protein Profile

Protein Summary

This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found\; however, their full-length nature has not been determined.

Gene names and symbols associated with ADCK3

  • aarF domain containing kinase 3 (ADCK3)
  • aarF domain containing kinase 3 (Adck3)
  • aarF domain containing kinase 3 (adck3)
  • 4632432J16Rik protein
  • AI462003 protein
  • ARCA2 protein
  • cabc1 protein
  • COQ8 protein
  • COQ10D4 protein
  • mKIAA0451 protein
  • SCAR9 protein

Protein level used designations for ADCK3

aarF domain containing kinase 3 , chaperone activity of bc1 complex-like, mitochondrial-like , aarF domain-containing protein kinase 3 , chaperone activity of bc1 complex-like, mitochondrial , chaperone, ABC1 activity of bc1 complex homolog , coenzyme Q8 homolog , chaperone, ABC1 activity of bc1 complex like , chaperone, ABC1 activity of bc1 complex homolog (S. pombe) , chaperone-ABC1-like , chaperone, ABC1 activity of bc1 complex-like

GENE ID SPECIES
100525602 Sus scrofa
56997 Homo sapiens
67426 Mus musculus
360887 Rattus norvegicus
480108 Canis lupus familiaris
536925 Bos taurus
416745 Gallus gallus
437001 Danio rerio
Selected quality suppliers for ADCK3 Proteins (ADCK3)
Did you look for something else?