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anti-Abhydrolase Domain Containing 5 (ABHD5) Antibodies

The protein encoded by ABHD5 belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. Additionally we are shipping ABHD5 Proteins (9) and ABHD5 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABHD5 51099 Q8WTS1
ABHD5 67469 Q9DBL9
ABHD5 316122 Q6QA69
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Top anti-ABHD5 Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated IHC, WB WB Suggested Anti-ABHD5 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated ELISA, WB ABIN190850 (1µg/ml) staining of A431 cell line lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Mouse Un-conjugated WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of ABHD5 expression in A-431. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of ABHD5 expression in transfected 293T cell line by ABHD5 monoclonal antibody (M01), clone 1F3. Lane 1: ABHD5 transfected lysate(39 KDa). Lane 2: Non-transfected lysate. Immunoperoxidase of monoclonal antibody to ABHD5 on formalin-fixed paraffin-embedded human small Intestine (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA, WB ABHD5 monoclonal antibody (M02), clone 4B12 Western Blot analysis of ABHD5 expression in A-431 . Detection limit for recombinant GST tagged ABHD5 is 0.3 ng/ml as a capture antibody. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to ABHD5 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3 ug/ml] Western Blot analysis of ABHD5 expression in transfected 293T cell line by ABHD5 monoclonal antibody (M01), clone 1F3.Lane 1: ABHD5 transfected lysate(39 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$430.00
Details
Human Goat Un-conjugated IHC (p), ELISA, WB Human Pancreas: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details

ABHD5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine) ,
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Rat (Rattus) ,
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Top referenced anti-ABHD5 Antibodies

  1. Human Monoclonal ABHD5 Primary Antibody for IHC (p), ELISA - ABIN565526 : Kinney, Qiao, Levaugh, Shao: B56alpha/protein phosphatase 2A inhibits adipose lipolysis in high-fat diet-induced obese mice. in Endocrinology 2010 (PubMed)
    Show all 11 references for ABIN565526

  2. Human Monoclonal ABHD5 Primary Antibody for WB - ABIN396214 : Lan, Fu, Liu, Huang, Chang, Liu, Peng, Chen: High frequency of ETFDH c.250G>A mutation in Taiwanese patients with late-onset lipid storage myopathy. in Clinical genetics 2010 (PubMed)
    Show all 5 references for ABIN396214

  3. Human Monoclonal ABHD5 Primary Antibody for WB - ABIN395090 : Schweiger, Lass, Zimmermann, Eichmann, Zechner: Neutral lipid storage disease: genetic disorders caused by mutations in adipose triglyceride lipase/PNPLA2 or CGI-58/ABHD5. in American journal of physiology. Endocrinology and metabolism 2009 (PubMed)
    Show all 5 references for ABIN395090

  4. Human Monoclonal ABHD5 Primary Antibody for ELISA, WB - ABIN565527 : Watt, van Denderen, Castelli, Bruce, Hoy, Kraegen, Macaulay, Kemp: Adipose triglyceride lipase regulation of skeletal muscle lipid metabolism and insulin responsiveness. in Molecular endocrinology (Baltimore, Md.) 2008 (PubMed)
    Show all 3 references for ABIN565527

  5. Human Polyclonal ABHD5 Primary Antibody for ELISA, WB - ABIN190850 : Lass, Zimmermann, Haemmerle, Riederer, Schoiswohl, Schweiger, Kienesberger, Strauss, Gorkiewicz, Zechner: Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome. in Cell metabolism 2006 (PubMed)
    Show all 2 references for ABIN190850

  6. Dog (Canine) Polyclonal ABHD5 Primary Antibody for WB - ABIN374842 : Koltes, Spurlock: Coordination of lipid droplet-associated proteins during the transition period of Holstein dairy cows. in Journal of dairy science 2011 (PubMed)

  7. Cow (Bovine) Polyclonal ABHD5 Primary Antibody for WB - ABIN2775424 : Bruno, Bertini, Di Rocco, Cassandrini, Ruffa, De Toni, Seri, Spada, Li Volti, DAmico, Trucco, Arca, Casali, Angelini, Dimauro, Minetti: Clinical and genetic characterization of Chanarin-Dorfman syndrome. in Biochemical and biophysical research communications 2008 (PubMed)

More Antibodies against ABHD5 Interaction Partners

Human Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. Authors show that rat ATGL (show PNPLA2 Antibodies), coactivated by rat CGI-58, efficiently hydrolyzes triglycerides and retinyl ester.

  2. novel ABHD5 truncating variant in a twenty nine month old female child, who presented with icthyosiform erythroderma.

  3. simultaneous tryptophan alanine permutations in both arms abolish localization and activity of CGI-58 as opposed to tryptophan substitutions that occur in only one arm.

  4. this study presents clinical and molecular data of four affected relatives with Chanarin-Dorfman syndrome homozygous for a N209X mutation in ABHD5, and provides a short review by comparing patients with N209X homozygous mutations to patients with other ABHD5 mutations.

  5. PLIN5 (show PLIN5 Antibodies) was significantly colocated with ATGL (show PNPLA2 Antibodies), mitochondria and CGI-58, indicating a close association between the key lipolytic effectors in resting skeletal muscle.

  6. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (show PLIN1 Antibodies) 1A-coated lipid droplets

  7. Abhd5 expression falls substantially and correlates negatively with malignant features in human colorectal cancer.

  8. Findings indicate a molecular mechanisms by which lysophosphatidic acid acyltransferase (show MBOAT2 Antibodies) CGI-58 regulates lipid homeostasis.

  9. ABHD5, PGRMC1 (show PGRMC1 Antibodies) and SQS (show FDFT1 Antibodies) are novel markers for sebaceous carcinoma and can reliably distinguish sebaceous neoplasms from non-sebaceous tumors, specifically BCC with clear cell features.

  10. A report of two Chanarin-Dorfman syndrome sisters with severe steatohepatitis and decompensated cirrhosis due to steatohepatitis in whom the clinical presentation developed due to a new mutation in ABHD5 gene.

Mouse (Murine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. Here, we identify synthetic ligands that release ABHD5 from PLIN1 (show PLIN1 Antibodies) or PLIN5 (show PLIN5 Antibodies) without PKA activation and rapidly activate adipocyte and muscle lipolysis.

  2. we identify adipocyte-type fatty acid-binding protein (A-Fabp (show FABP4 Antibodies)) and other members of the fatty acid-binding protein (Fabp (show FABP Antibodies)) family as interaction partners of Cgi-58.

  3. Data (including data from studies in atherosclerotic knockout mice) suggest CGI58-deficient macrophages store-up triglyceride-rich droplets and have reduced phagocytic capacity, comparable to Atgl- (adipose triglyceride lipase (show PNPLA2 Antibodies)-)deficient macrophages.

  4. -mediated phosphorylation of CGI-58 is required for dispersion of CGI-58 from perilipin (show PLIN1 Antibodies) 1A-coated lipid droplets

  5. Muscle CGI-58 deficiency causes cardiac dysfunction and fat deposition in oxidative muscles but induces a series of favorable metabolic changes in mice fed a high-fat diet.

  6. intestinal CGI-58 is required for efficient postprandial lipoprotein-TG secretion and for maintaining hepatic and plasma lipid homeostasis.

  7. CGI-58 transgenic/ApoE (show APOE Antibodies)-/- mice exhibited an anti-atherosclerosis phenotype compared with wild type (WT) controls (CGI-58 WT/ApoE (show APOE Antibodies)-/-), illustrated by less plaque area in aortic roots.

  8. The anti-lipolytic activity of the HCV core protein alters ATGL (show PNPLA2 Antibodies) binding to CGI-58 and enhances the association of both proteins with lipid droplets.

  9. These data thus identified a vicious cycle (IL-1beta (show IL1B Antibodies)-SOCS3 (show SOCS3 Antibodies)-FOXO1 (show FOXO1 Antibodies)-IL-1beta (show IL1B Antibodies)) that amplifies IL-1beta (show IL1B Antibodies) secretion and is initiated by CGI-58 deficiency-induced activation of the NLRP3 (show NLRP3 Antibodies) inflammasome in macrophages.

  10. Perilipins 2 and 3 lack a carboxy-terminal domain present in perilipin 1 (show PLIN1 Antibodies) involved in sequestering ABHD5 and suppressing basal lipolysis.

Pig (Porcine) Abhydrolase Domain Containing 5 (ABHD5) interaction partners

  1. These findings suggest that CGI-58 may be a new target for enhancing the quality of pork products as well as offering the potential of CGI-58 for human obesity treatment.

ABHD5 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation.

Gene names and symbols associated with ABHD5

  • abhydrolase domain containing 5 (ABHD5) antibody
  • abhydrolase domain containing 5 (abhd5) antibody
  • abhydrolase domain containing 5a (abhd5a) antibody
  • abhydrolase domain containing 5 (LOC100229229) antibody
  • abhydrolase domain containing 5 (LOC100350162) antibody
  • abhydrolase domain containing 5 (Abhd5) antibody
  • 1300003D03Rik antibody
  • 2010002J10Rik antibody
  • abhd5 antibody
  • CDS antibody
  • CGI-58 antibody
  • CGI58 antibody
  • IECN2 antibody
  • IECN5 antibody
  • NCIE2 antibody

Protein level used designations for ABHD5

abhydrolase domain containing 5 , CGI58 protein , 1-acylglycerol-3-phosphate O-acyltransferase ABHD5 , abhydrolase domain-containing protein 5 , lipid droplet-binding protein CGI-58 , alpha/beta hydrolase domain-containing 5 , lipid droplet binding protein , Abhydrolase domain-containing protein 5

GENE ID SPECIES
460303 Pan troglodytes
549643 Xenopus (Silurana) tropicalis
566493 Danio rerio
100066775 Equus caballus
100229229 Taeniopygia guttata
100350162 Oryctolagus cuniculus
100125355 Ovis aries
51099 Homo sapiens
67469 Mus musculus
485570 Canis lupus familiaris
497624 Sus scrofa
535588 Bos taurus
316122 Rattus norvegicus
446400 Xenopus laevis
420673 Gallus gallus
100174407 Pongo abelii
Selected quality suppliers for anti-ABHD5 (ABHD5) Antibodies
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