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Abhydrolase Domain Containing 6 Proteins (ABHD6)

Has 2-arachidonoylglycerol hydrolase activity (By similarity). Additionally we are shipping ABHD6 Antibodies (25) and ABHD6 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ABHD6 57406 Q9BV23
ABHD6 66082 Q8R2Y0
Rat ABHD6 ABHD6 305795 Q5XI64
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Top ABHD6 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ABHD6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Abhydrolase Domain Containing 6 (ABHD6) Interaction Partners

Human Abhydrolase Domain Containing 6 (ABHD6) interaction partners

  1. data suggest that ABHD6 controls BMP catabolism and is therefore part of the late endosomal/lysosomal lipid-sorting machinery

  2. Results confirm the genetic association of the locus 3p14.3 with systemic lupus erythematosus in Europeans and point to the ABHD6 and not PXK (show PXK Proteins), as the major susceptibility gene in the region.

  3. ABHD6 increases from neonatal age.

  4. Data show that the three hydrolases are genuine MAG (show MAG Proteins) lipases; medium-chain saturated MAGs were the best substrates for hABHD6 and hMAGL, whereas hABHD12 preferred the 1 (3)- and 2-isomers of arachidonoylglycerol.

  5. High expression of ABHD6 in Ewing family tumors (EFT) in comparison to normal tissues and other tumors suggests that ABHD6 might be an interesting new diagnostic or therapeutic target for EFT.

  6. report the tissue distribution, subcellular location and differential distribution among cancer cell lines of Abhd6, one unannotated member of this group

Mouse (Murine) Abhydrolase Domain Containing 6 (ABHD6) interaction partners

  1. Whole-body and b-cell specific ABHD6-KO mice exhibit enhanced glucose-stimulated insulin (show INS Proteins) secretion, and their islets show elevated monoacylglycerol production and insulin (show INS Proteins) secretion in response to glucose.

  2. ABHD6 can hydrolyze several lipid substrates, positioning ABHD6 at the interface of glycerophospholipid metabolism and lipid signal transduction.

  3. Data suggest ABHD6 as a therapeutic target that could be relevant in treating inflammation-related conditions.

  4. FAAH (show FAAH Proteins) but not monoacyl glycerol lipase (show LIPG Proteins) exerts important protective actions against 2-arachidonoyl glycerol-induced cellular damage.

  5. Dual inhibition of alpha/beta-hydrolase domain 6 and fatty acid amide hydrolase (show FAAH Proteins) increases endocannabinoid levels in neurons.

  6. ABHD6 is a rate-limiting step of 2-AG signaling

  7. Data reveal that 85% of brain 2 (show POU3F2 Proteins)-arachidonoylglycerol hydrolase activity can be ascribed to monoacylglycerol lipase(MAGL (show MGLL Proteins)), and the remaining 15% is catalyzed by ABHD6 and ABHD12 (show ABHD12 Proteins).

ABHD6 Protein Profile

Protein Summary

Has 2-arachidonoylglycerol hydrolase activity (By similarity). May be a regulator of endocannabinoid signaling pathways (By similarity).

Gene names and symbols associated with ABHD6

  • abhydrolase domain containing 6 (abhd6-b)
  • abhydrolase domain containing 6 (ABHD6)
  • abhydrolase domain containing 6 (abhd6)
  • abhydrolase domain containing 6 (Abhd6)
  • 0610041D24Rik protein
  • AA673485 protein
  • ABHD6 protein
  • abhd6-b protein
  • AV065425 protein
  • MGC64518 protein

Protein level used designations for ABHD6

monoacylglycerol lipase abhd6-B , abhydrolase domain-containing protein 6-B , abhydrolase domain containing 6 , monoacylglycerol lipase ABHD6 , monoacylglycerol lipase ABHD6-like , 2-arachidonoylglycerol hydrolase , abhydrolase domain-containing protein 6 , lipase protein

GENE ID SPECIES
380544 Xenopus laevis
416009 Gallus gallus
470830 Pan troglodytes
702384 Macaca mulatta
100057821 Equus caballus
100145783 Xenopus (Silurana) tropicalis
100399741 Callithrix jacchus
100433718 Pongo abelii
100482314 Ailuropoda melanoleuca
100515411 Sus scrofa
100355792 Oryctolagus cuniculus
100603829 Nomascus leucogenys
57406 Homo sapiens
484712 Canis lupus familiaris
505283 Bos taurus
66082 Mus musculus
305795 Rattus norvegicus
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