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The product of ACAT2 is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. Additionally we are shipping ACAT2 Proteins (10) and ACAT2 Kits (4) and many more products for this protein.
Showing 10 out of 79 products:
Cow (Bovine) Polyclonal ACAT2 Primary Antibody for IHC, WB - ABIN2777595
Sakashita, Miyazaki, Chang, Chang, Kiyota, Satoh, Komohara, Morganelli, Horiuchi, Takeya: Acyl-coenzyme A:cholesterol acyltransferase 2 (ACAT2) is induced in monocyte-derived macrophages: in vivo and in vitro studies. in Laboratory investigation; a journal of technical methods and pathology 2003
results show that the enzymatic activity of mutant Glu(14)Gly is approximately two times higher than wildtype, and that this increase is primarily due to the increased expression and/or stability of the mutant ACAT2 protein
Results show that DLAT (show DLAT Antibodies) and ACAT2 as upstream acetyltransferases of K76 and K294 in 6PGD (show PGD Antibodies) protein.
Reduced ACAT2 is associated with impaired butyrate oxidation in ulcerative colitis.
HNF4alpha positively regulates ACAT2 gene expression at mRNA level. Overexpression of HNF4alpha increased ACAT2 expression, whereas knockdown of HNF4alpha decreased ACAT2 expression.
Describe a gender-related difference in hepatic ACAT2 activity in normolipidemic non-obese Chinese patients suggesting a possible role for ACAT2 in the regulation of cholesterol metabolism in humans.
Data describe the high resolution structure of human cytosolic acetoacetyl-CoA thiolase (CT), both unliganded (at 2.3 angstroms resolution) and in complex with CoA (at 1.6 angstroms resolution).
human ACAT2 is transcriptionally regulated by cholesterol.
ACAT2 expression was induced upon R1881 (androgen agonist) treatment in prostate cancer cells
ACAT-2 expression was negative in clear cell type renal cell carcinoma (show MOK Antibodies) and normal kidney.
The increased NPC1L1 and ACAT2 mRNA levels in gallstone patients might indicate an upregulated absorption and esterification of cholesterol in the small intestine.
Intestine-specific MTP (show LAPTM4A Antibodies) and global ACAT2 (show SOAT2 Antibodies) deficiency lowers acute cholesterol absorption with chylomicrons and HDLs (show CSF1R Antibodies)
ACAT2 (show SOAT2 Antibodies) seems to be a hepatic player affecting the cholesterol fluxes fated to VLDL or to HDL (show HSD11B1 Antibodies), the latter via up-regulation of ABCA1 (show ABCA1 Antibodies)
handling of sterols by the intestine involves both G5G8 and ACAT2 but that an additional factor (possibly Niemann-Pick C1-like 1) may be key in determining absorption efficiency
inhibition of intestinal or hepatic ACAT2 improves atherogenic hyperlipidemia and limits hepatic cholesteryl ester accumulation
Pyripyropene ACAT2-selective inhibition in the intestine and the liver can be effective against atherosclerosis.
Inhibition of acyl-coenzyme A:cholesterol acyltransferase 2 (show SOAT2 Antibodies) prevents dietary cholesterol-associated steatosis by enhancing hepatic triglyceride mobilization.
ACAT2 (show SOAT2 Antibodies) provides core CE of newly secreted VLDL, whereas LCAT (show LCAT Antibodies) adds CE during LDL particle formation
ABCA1 (show ABCA1 Antibodies), especially in the absence of ACAT2 (show SOAT2 Antibodies), can have a significant effect on cholesterol absorption, although ACAT2 (show SOAT2 Antibodies) has a more substantial role in this process than ABCA1 (show ABCA1 Antibodies)
depletion of hepatic ACAT2-driven cholesterol esterification reveals a non-biliary route for fecal neutral sterol loss
The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation.
acetoacetyl Coenzyme A thiolase
, acetyl-CoA acetyltransferase, cytosolic
, acetyl-CoA transferase-like protein
, cytosolic acetoacetyl-CoA thiolase
, acetyl-Coenzyme A acetyltransferase 2
, acetyl-Coenzyme A acetyltransferase 3
, acetyl-Coenzyme A acetyltransferase 2 (acetoacetyl Coenzyme A thiolase)
, t-complex protein 1, related sequence 1