anti-Acetyl-CoA Acetyltransferase 1 (ACAT1) Antibodies

ACAT1 encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Additionally we are shipping ACAT1 Kits (15) and ACAT1 Proteins (13) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACAT1 38 P24752
ACAT1 25014 P17764
ACAT1 110446 Q8QZT1
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Top anti-ACAT1 Antibodies at antibodies-online.com

Showing 10 out of 165 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ACAT1 Pab (ABIN391807) in SK-BR-3 cell line lysates (35 µg/lane).ACAT1 (arrow) was detected using the purified polyclonal antibody (1:60 dilution). Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ACAT1 antibody (C-term) (ABIN391807), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ACAT1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-ACAT1 Pab in SK-BR-3 cell line lysates (35ug/lane).ACAT1 (arrow) was detected using the purified Pab (1:60 dilution). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Cow Rabbit Un-conjugated IHC, WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated IHC (p), WB Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7 to 9 Days
$676.50
Details
Hamster Rabbit Un-conjugated ICC, IF, IP, WB   0.1 mL Log in to see 7 to 9 Days
$381.94
Details
Bat Goat Un-conjugated ELISA, WB 100 μg Log in to see 7 to 9 Days
$610.50
Details
Human Goat Un-conjugated ELISA, WB Western Blot: ACAT1 Antibody [NBP1-51994] - Analysis of Mouse (A) and Rat (B) kidney lysates, and Mouse (C) and Rat (D) Liver lysates (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: ACAT1 Antibody [NBP1-51994] - (0.01ug/ml) staining of Human Liver lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details

ACAT1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ACAT1 Antibodies

  1. Human Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN4277536 : Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. in Journal of proteomics 2012 (PubMed)
    Show all 5 Pubmed References

  2. Hamster Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN152908 : Chang, Chen, Thomas, Cheng, Del Priore, Newton, Pape, Chang: Regulation and immunolocalization of acyl-coenzyme A: cholesterol acyltransferase in mammalian cells as studied with specific antibodies. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal ACAT1 Primary Antibody for ICC, IF - ABIN4277537 : Sanchez-Alvarez, Martinez-Outschoorn, Lin, Lamb, Hulit, Howell, Sotgia, Rubin, Lisanti: Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention. in Cell cycle (Georgetown, Tex.) 2013 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal ACAT1 Primary Antibody for ELISA, WB - ABIN4277535 : Hongo, Watanabe, Arita, Kanome, Kageyama, Shioda, Miyazaki: Leptin modulates ACAT1 expression and cholesterol efflux from human macrophages. in American journal of physiology. Endocrinology and metabolism 2009 (PubMed)

  5. Polyclonal ACAT1 Primary Antibody for IP, WB - ABIN540796 : Song, Kost, Martin: Androgens augment renal vascular responses to ANG II in New Zealand genetically hypertensive rats. in American journal of physiology. Regulatory, integrative and comparative physiology 2006 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ACAT1 Interaction Partners

Human Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. these results illustrate that ACAT1-catalyzed esterification of 24S-OHC with long-chain unsaturated fatty acid followed by formation of atypical LD-like structures at the ER membrane is a critical requirement for 24S-OHC-induced cell death.

  2. ACAT1 exonic mutations that affect ESE sequences may result in aberrant splicing. This may affect the activity of mitochondrial acetoacetyl-CoA thiolase.

  3. TLR4 (show TLR4 Antibodies) siRNA inhibits cell proliferation, migration and invasion by suppressing ACAT1 expression, suggesting that TLR4 (show TLR4 Antibodies) may be a potential therapeutic target for the treatment of colorectal cancer

  4. ACAT1 has a role in regulating the dynamics of free cholesterols in plasma membrane which leads to the APP (show APP Antibodies)-alpha-processing alteration

  5. compound heterozygous of ACAT1 gene mutations probably underlie the beta-ketothiolase deficiency in our patient

  6. ACAT1 regulates glioblastoma-cell proliferation via modification of the Akt (show AKT1 Antibodies) and/or the ERK1/2 (show MAPK1/3 Antibodies) pathway.

  7. Data indicate that acetyl-CoA (show LPCAT2 Antibodies) acetyltransferase (ACAT1) and malate dehydrogenase (MDH2 (show MDH Antibodies)) are involved in various drug-resistance-forming mechanisms.

  8. ACAT1, ACACA (show ACACA Antibodies), ALDH6A1 (show ALDH6A1 Antibodies) and MTHFD1 (show MTHFD1 Antibodies) represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals.

  9. Data show that the C allele of acyl-CoA (show GNPAT Antibodies) acyltransferase-1 (ACAT-1) rs1044925 was associated with a decreased risk of coronary artery disease and ischemic stroke patients.

  10. Acat1 gene knock-out increases phagocytic uptake of amyloid beta-protein (1 (show DLX4 Antibodies)-42).

Cow (Bovine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. The transcript abundance of ACAT1 was increased in the more efficient low residual feed intake (RFI (show RNF34 Antibodies)) animals and decreased in the less efficient high RFI (show RNF34 Antibodies) animals

Mouse (Murine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. Data show that microRNA miR (show MLXIP Antibodies)-467b regulates the acetyl-CoA acetyltransferase 1 (ACAT1) expression via targeting ACAT1 (show SOAT1 Antibodies) 3' untranslated regions (3'UTR (show UTS2R Antibodies)).

  2. In a mouse model, targeting ACAT1 (show SOAT1 Antibodies) specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages.

  3. Oxidized low-density lipoprotein activated the TLR4 (show TLR4 Antibodies)/MyD88 (show MYD88 Antibodies)/NF-kappaB (show NFKB1 Antibodies) inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 (show SOAT1 Antibodies) expression and promotes VSMC foam cell formation.

  4. Exacerbation of liver fibrosis by ACAT1 (show SOAT1 Antibodies) deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 (show TLR4 Antibodies) signaling.

  5. ACAT1 (show SOAT1 Antibodies) plays important roles in hematopoiesis in normal mouse and in Apoe (show APOE Antibodies)(-/-) mouse during atherosclerosis development.

  6. ApoA-I (show APOA1 Antibodies) Helsinki promotes accumulation of ACAT1 (show SOAT1 Antibodies) in a mouse macrophage cell line.

  7. the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT (show SOAT1 Antibodies) inhibition in addition to potent inhibition of macrophage ACAT-1 (show SOAT1 Antibodies)

  8. ACAT1 (show SOAT1 Antibodies) gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease.

  9. ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol

  10. ACAT1 (show SOAT1 Antibodies) knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1.

ACAT1 Antigen Profile

Protein Summary

This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

Gene names and symbols associated with ACAT1

  • acetyl-CoA acetyltransferase 1 (ACAT1) antibody
  • acetyl-CoA acetyltransferase 1 (Acat1) antibody
  • acetyl-CoA acetyltransferase 1 (acat1) antibody
  • acetyl-Coenzyme A acetyltransferase 1 (Acat1) antibody
  • acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (acat1) antibody
  • 6330585C21Rik antibody
  • Acat antibody
  • acat1-a antibody
  • fd16h07 antibody
  • fd20g06 antibody
  • MAT antibody
  • RATACAL antibody
  • T2 antibody
  • THIL antibody
  • wu:fd16h07 antibody
  • wu:fd20g06 antibody
  • zgc:86832 antibody

Protein level used designations for ACAT1

acetyl-CoA acetyltransferase 1 , acetoacetyl Coenzyme A thiolase , acetoacetyl-CoA thiolase , acetyl-CoA acetyltransferase, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 , mitochondrial acetoacetyl-CoA thiolase , acetyl-Co A acetyltransferase 1 mitochondrial , acetyl-coenzyme A acetyltransferase 1 , Acetoacetyl-CoA thiolase A , acetyl-CoA acetyltransferase A, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)

GENE ID SPECIES
100597123 Nomascus leucogenys
100626793 Sus scrofa
38 Homo sapiens
25014 Rattus norvegicus
414639 Xenopus laevis
418968 Gallus gallus
511082 Bos taurus
489421 Canis lupus familiaris
110446 Mus musculus
445290 Danio rerio
Selected quality suppliers for anti-ACAT1 (ACAT1) Antibodies
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