Acetyl-CoA Acetyltransferase 1 Proteins (ACAT1)

ACAT1 encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Additionally we are shipping ACAT1 Antibodies (165) and ACAT1 Kits (15) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACAT1 38 P24752
ACAT1 25014 P17764
ACAT1 110446 Q8QZT1
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ACAT1 Proteins at antibodies-online.com

Showing 10 out of 13 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$319.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 60 to 71 Days
$3,067.17
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 60 to 71 Days
$3,067.17
Details
Yeast Cow His tag   1 mg Log in to see 60 to 71 Days
$3,089.17
Details
Yeast Macaca fascicularis His tag   1 mg Log in to see 60 to 71 Days
$3,089.17
Details
Yeast Rat His tag   1 mg Log in to see 60 to 71 Days
$3,089.17
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$384.00
Details

ACAT1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Rat (Rattus)

Mouse (Murine) ,
,

More Proteins for Acetyl-CoA Acetyltransferase 1 (ACAT1) Interaction Partners

Human Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. these results illustrate that ACAT1-catalyzed esterification of 24S-OHC with long-chain unsaturated fatty acid followed by formation of atypical LD-like structures at the ER membrane is a critical requirement for 24S-OHC-induced cell death.

  2. ACAT1 exonic mutations that affect ESE sequences may result in aberrant splicing. This may affect the activity of mitochondrial acetoacetyl-CoA thiolase.

  3. TLR4 (show TLR4 Proteins) siRNA inhibits cell proliferation, migration and invasion by suppressing ACAT1 expression, suggesting that TLR4 (show TLR4 Proteins) may be a potential therapeutic target for the treatment of colorectal cancer

  4. ACAT1 has a role in regulating the dynamics of free cholesterols in plasma membrane which leads to the APP (show APP Proteins)-alpha-processing alteration

  5. compound heterozygous of ACAT1 gene mutations probably underlie the beta-ketothiolase deficiency in our patient

  6. ACAT1 regulates glioblastoma-cell proliferation via modification of the Akt and/or the ERK1/2 pathway.

  7. Data indicate that acetyl-CoA (show LPCAT2 Proteins) acetyltransferase (ACAT1) and malate dehydrogenase (MDH2 (show MDH Proteins)) are involved in various drug-resistance-forming mechanisms.

  8. ACAT1, ACACA, ALDH6A1 (show ALDH6A1 Proteins) and MTHFD1 (show MTHFD1 Proteins) represent novel biomarkers in adipose tissue associated with type 2 diabetes in obese individuals.

  9. Data show that the C allele of acyl-CoA (show GNPAT Proteins) acyltransferase-1 (ACAT-1) rs1044925 was associated with a decreased risk of coronary artery disease and ischemic stroke patients.

  10. Acat1 gene knock-out increases phagocytic uptake of amyloid beta-protein (1 (show DLX4 Proteins)-42).

Cow (Bovine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. The transcript abundance of ACAT1 was increased in the more efficient low residual feed intake (RFI (show RNF34 Proteins)) animals and decreased in the less efficient high RFI (show RNF34 Proteins) animals

Mouse (Murine) Acetyl-CoA Acetyltransferase 1 (ACAT1) interaction partners

  1. Data show that microRNA miR (show MLXIP Proteins)-467b regulates the acetyl-CoA acetyltransferase 1 (ACAT1) expression via targeting ACAT1 (show SOAT1 Proteins) 3' untranslated regions (3'UTR).

  2. In a mouse model, targeting ACAT1 (show SOAT1 Proteins) specifically in a myeloid lineage may benefit atherosclerosis progression by reducing the infiltration of foamy macrophages.

  3. Oxidized low-density lipoprotein activated the TLR4 (show TLR4 Proteins)/MyD88 (show MYD88 Proteins)/NF-kappaB (show NFKB1 Proteins) inflammatory signaling pathway in vascular smooth muscle cell, which upregulates the ACAT1 (show SOAT1 Proteins) expression and promotes VSMC foam cell formation.

  4. Exacerbation of liver fibrosis by ACAT1 (show SOAT1 Proteins) deficiency was dependent on free cholesterol accumulation-induced enhancement of TLR4 (show TLR4 Proteins) signaling.

  5. ACAT1 (show SOAT1 Proteins) plays important roles in hematopoiesis in normal mouse and in Apoe (show APOE Proteins)(-/-) mouse during atherosclerosis development.

  6. ApoA-I (show APOA1 Proteins) Helsinki promotes accumulation of ACAT1 (show SOAT1 Proteins) in a mouse macrophage cell line.

  7. the plaque-modulating effects of K-604 can be explained by stimulation of procollagen production independent of ACAT (show SOAT1 Proteins) inhibition in addition to potent inhibition of macrophage ACAT-1 (show SOAT1 Proteins)

  8. ACAT1 (show SOAT1 Proteins) gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with Alzheimer disease.

  9. ACAT1 displays less capacity than ACAT2 to differentiate cholesterol from sitosterol

  10. ACAT1 (show SOAT1 Proteins) knockout macrophages show biochemical changes consistent with increased cytotoxicity and also a novel association with decreased expression of collagen type 3A1.

ACAT1 Protein Profile

Protein Summary

This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone.

Gene names and symbols associated with ACAT1

  • acetyl-CoA acetyltransferase 1 (ACAT1)
  • acetyl-CoA acetyltransferase 1 (Acat1)
  • acetyl-CoA acetyltransferase 1 (acat1)
  • acetyl-Coenzyme A acetyltransferase 1 (Acat1)
  • acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) (acat1)
  • 6330585C21Rik protein
  • Acat protein
  • acat1-a protein
  • fd16h07 protein
  • fd20g06 protein
  • MAT protein
  • RATACAL protein
  • T2 protein
  • THIL protein
  • wu:fd16h07 protein
  • wu:fd20g06 protein
  • zgc:86832 protein

Protein level used designations for ACAT1

acetyl-CoA acetyltransferase 1 , acetoacetyl Coenzyme A thiolase , acetoacetyl-CoA thiolase , acetyl-CoA acetyltransferase, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 , mitochondrial acetoacetyl-CoA thiolase , acetyl-Co A acetyltransferase 1 mitochondrial , acetyl-coenzyme A acetyltransferase 1 , Acetoacetyl-CoA thiolase A , acetyl-CoA acetyltransferase A, mitochondrial , acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase)

GENE ID SPECIES
100597123 Nomascus leucogenys
100626793 Sus scrofa
38 Homo sapiens
25014 Rattus norvegicus
414639 Xenopus laevis
418968 Gallus gallus
511082 Bos taurus
489421 Canis lupus familiaris
110446 Mus musculus
445290 Danio rerio
Selected quality suppliers for ACAT1 Proteins (ACAT1)
Did you look for something else?