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ASCL1 encodes a member of the basic helix-loop-helix (BHLH) family of transcription factors. Additionally we are shipping Achaete-Scute Complex Homolog 1 (Drosophila) Kits (21) and Achaete-Scute Complex Homolog 1 (Drosophila) Proteins (7) and many more products for this protein.
Showing 10 out of 136 products:
Mouse (Murine) Monoclonal ASCL1 Primary Antibody for WB - ABIN967560
Hu, Ippolito, Garabedian, Humphrey, Gordon: Molecular characterization of a metastatic neuroendocrine cell cancer arising in the prostates of transgenic mice. in The Journal of biological chemistry 2002
Show all 6 references for ABIN967560
Human Polyclonal ASCL1 Primary Antibody for WB - ABIN1881074
Phi, Kim, Eun, Wang, Park, Choi, Kim, Park, Cho, Kim: Upregulation of SOX2, NOTCH1, and ID1 in supratentorial primitive neuroectodermal tumors: a distinct differentiation pattern from that of medulloblastomas. in Journal of neurosurgery. Pediatrics 2010
Show all 5 references for ABIN1881074
Cow (Bovine) Polyclonal ASCL1 Primary Antibody for IHC, WB - ABIN2779585
Somasundaram, Reddy, Vinnakota, Britto, Subbarayan, Nambiar, Hebbar, Samuel, Shetty, Sreepathi, Santosh, Hegde, Hegde, Kondaiah, Rao: Upregulation of ASCL1 and inhibition of Notch signaling pathway characterize progressive astrocytoma. in Oncogene 2005
Show all 3 references for ABIN2779585
Mouse (Murine) Monoclonal ASCL1 Primary Antibody for IHC, WB - ABIN2668587
Lo, Johnson, Wuenschell, Saito, Anderson: Mammalian achaete-scute homolog 1 is transiently expressed by spatially restricted subsets of early neuroepithelial and neural crest cells. in Genes & development 1991
Show all 3 references for ABIN2668587
Human Polyclonal ASCL1 Primary Antibody for EIA, IHC (p) - ABIN357401
Sriuranpong, Borges, Strock, Nakakura, Watkins, Blaumueller, Nelkin, Ball: Notch signaling induces rapid degradation of achaete-scute homolog 1. in Molecular and cellular biology 2002
Show all 2 references for ABIN357401
Human Polyclonal ASCL1 Primary Antibody for WB - ABIN388761
Renault, Lieman, Ward, Krauter, Kucherlapati: Localization of the human achaete-scute homolog gene (ASCL1) distal to phenylalanine hydroxylase (PAH) and proximal to tumor rejection antigen (TRA1) on chromosome 12q22-q23. in Genomics 1996
Chicken Polyclonal ASCL1 Primary Antibody for WB - ABIN2792096
Osada, Tomida, Yatabe, Tatematsu, Takeuchi, Murakami, Kondo, Sekido, Takahashi: Roles of achaete-scute homologue 1 in DKK1 and E-cadherin repression and neuroendocrine differentiation in lung cancer. in Cancer research 2008
These results establish maternal Asc1l as a key factor in establishing pre-patterning of the early embryo, acting in opposition to VegT and biasing the animal pole to adopt neural fates.
analysis of cell-cycle-dependent phosphorylation of the key reprogramming transcription factor Ascl1 on multiple serine-proline sites
This report identifies novel roles (show DDC Antibodies)for the transcription factor Ascl1 in enteric gliogenesis and neurogenesis
ASCL1 expression is regulated by BRD4 (show BRD4 Antibodies) is frequently overexpressed in small cell lung cancer.
Data show that chrysin suppressed cell proliferation and reducing expression of achaete-scute complex-like 1 (ASCL1) and the neuroendocrine biomarker chromogranin A (CgA (show CHGA Antibodies)).
hASH1 is a specific marker to distinguish neuroendocrine tumors from squamous cell carcinomas and adenocarcinomas
Structural features were identified in ASH1L (show ASH1L Antibodies) related to its' function and enzymatic activity.
Both ASH1L (show ASH1L Antibodies) and SETD2 (show SETD2 Antibodies) are H3K36 specific methyltransferases but only SETD2 (show SETD2 Antibodies) can trimethylate this mark.
These data demonstrate that miR (show MLXIP Antibodies)-142-3p downregulation has a role in thyroid tumorigenesis, by regulating ASH1L (show ASH1L Antibodies) and MLL1.
Achaete-scute homolog 1 (ASCL1), a transcription factor required for proper development of pulmonary neuroendocrine cells, is essential for the survival of a majority of lung cancers with neuroendocrine features.
data suggest that a prominent down-regulation of hnRNP-A2/B1 (show HNRNPA2B1 Antibodies) during hypoxia is associated with the post-transcriptional suppression of hASH1 synthesis.
ASCL1 and RET (show RET Antibodies) expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation.
we observe that the early-born 5-HT (show DDC Antibodies)(+) neurons are generated in Ascl1(-/-) mutants
the combination of gain- and loss-of-function experiments in the developing midbrain showed co-operative roles for Mgn (show HELT Antibodies) and Mash1 genes in determining GABAergic identity.
This study findings demonstrate that Ascl1(CreERT2) and Glast (show SLC1A3 Antibodies)(CreERT2) mouse lines enable simple and reliable labeling of adult-born GC lineages within restricted time windows.
results show that at least one of the differences between mammal and fish Muller glia that bears on their difference in regenerative potential is the proneural transcription factor Ascl1
This suggests that the maintenance of ASCL1 in its multiply phosphorylated state might prevent terminal differentiation in neuroblastoma (show ARHGEF16 Antibodies).
CPAP (show CENPJ Antibodies) regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1.
a single transcription factor, Ascl1, is sufficient to convert brain astrocytes into functional neurons
Mash1 is required for the expression of GAD67 (show GAD1 Antibodies) and Dlx5 (show DLX5 Antibodies) in taste bud cells.
the prethalamic factors Dlxs upregulated by Ascl1/Helt (show HELT Antibodies) deficiency play unique roles in regulating thalamic progenitor specification.
GABAergic inducing activity of Ascl1 requires the direct transcriptional regulation of Ptf1a (show PTF1A Antibodies).
This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions.
achaete-scute complex homolog 1 (Drosophila)
, achaete-scute complex-like 1
, achaete-scute homolog 1
, achaete scute protein
, class A basic helix-loop-helix protein 46
, achaete-scute complex homolog-like 1
, mammalian achaete scute homolog 1
, achaete-scute complex homolog 1
, achaete-scute homolog 2
, transcription factor cash4
, ASH1-like protein
, absent small and homeotic disks protein 1 homolog
, histone-lysine N-methyltransferase ASH1L
, lysine N-methyltransferase 2H
, probable histone-lysine N-methyltransferase ASH1L