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Achaete-Scute Complex Homolog 1 (Drosophila) Proteins (ASCL1)

ASCL1 encodes a member of the trithorax group of transcriptional activators. Additionally we are shipping Achaete-Scute Complex Homolog 1 (Drosophila) Antibodies (136) and Achaete-Scute Complex Homolog 1 (Drosophila) Kits (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ASCL1 429 P50553
ASCL1 17172 Q02067
ASCL1 64186 P19359
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Top Achaete-Scute Complex Homolog 1 (Drosophila) Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
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Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,588.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
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ASCL1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) Interaction Partners

Xenopus laevis Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) interaction partners

  1. These results establish maternal Asc1l as a key factor in establishing pre-patterning of the early embryo, acting in opposition to VegT and biasing the animal pole to adopt neural fates.

  2. analysis of cell-cycle-dependent phosphorylation of the key reprogramming transcription factor Ascl1 on multiple serine-proline sites

Human Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) interaction partners

  1. This report identifies novel roles (show DDC Proteins)for the transcription factor Ascl1 in enteric gliogenesis and neurogenesis

  2. ASCL1 expression is regulated by BRD4 (show BRD4 Proteins) is frequently overexpressed in small cell lung cancer.

  3. Data show that chrysin suppressed cell proliferation and reducing expression of achaete-scute complex-like 1 (ASCL1) and the neuroendocrine biomarker chromogranin A (CgA (show CHGA Proteins)).

  4. hASH1 is a specific marker to distinguish neuroendocrine tumors from squamous cell carcinomas and adenocarcinomas

  5. Structural features were identified in ASH1L (show ASH1L Proteins) related to its' function and enzymatic activity.

  6. Both ASH1L and SETD2 are H3K36 specific methyltransferases but only SETD2 can trimethylate this mark.

  7. These data demonstrate that miR (show MLXIP Proteins)-142-3p downregulation has a role in thyroid tumorigenesis, by regulating ASH1L (show ASH1L Proteins) and MLL1.

  8. Achaete-scute homolog 1 (ASCL1), a transcription factor required for proper development of pulmonary neuroendocrine cells, is essential for the survival of a majority of lung cancers with neuroendocrine features.

  9. data suggest that a prominent down-regulation of hnRNP-A2/B1 (show HNRNPA2B1 Proteins) during hypoxia is associated with the post-transcriptional suppression of hASH1 synthesis.

  10. ASCL1 and RET (show RET Proteins) expression defines a clinically relevant subgroup of lung adenocarcinoma characterized by neuroendocrine differentiation.

Mouse (Murine) Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) interaction partners

  1. we observe that the early-born 5-HT (show DDC Proteins)(+) neurons are generated in Ascl1(-/-) mutants

  2. the combination of gain- and loss-of-function experiments in the developing midbrain showed co-operative roles for Mgn (show HELT Proteins) and Mash1 genes in determining GABAergic identity.

  3. This study findings demonstrate that Ascl1(CreERT2) and Glast (show SLC1A3 Proteins)(CreERT2) mouse lines enable simple and reliable labeling of adult-born GC lineages within restricted time windows.

  4. results show that at least one of the differences between mammal and fish Muller glia that bears on their difference in regenerative potential is the proneural transcription factor Ascl1

  5. This suggests that the maintenance of ASCL1 in its multiply phosphorylated state might prevent terminal differentiation in neuroblastoma (show ARHGEF16 Proteins).

  6. CPAP (show CENPJ Proteins) regulates progenitor divisions and neuronal migration in the cerebral cortex downstream of Ascl1.

  7. a single transcription factor, Ascl1, is sufficient to convert brain astrocytes into functional neurons

  8. Mash1 is required for the expression of GAD67 (show GAD1 Proteins) and Dlx5 (show DLX5 Proteins) in taste bud cells.

  9. the prethalamic factors Dlxs upregulated by Ascl1/Helt (show HELT Proteins) deficiency play unique roles in regulating thalamic progenitor specification.

  10. GABAergic inducing activity of Ascl1 requires the direct transcriptional regulation of Ptf1a (show PTF1A Proteins).

Achaete-Scute Complex Homolog 1 (Drosophila) (ASCL1) Protein Profile

Protein Summary

This gene encodes a member of the trithorax group of transcriptional activators. The protein contains four AT hooks, a SET domain, a PHD-finger motif, and a bromodomain. It is localized to many small speckles in the nucleus, and also to cell-cell tight junctions.

Gene names and symbols associated with ASCL1

  • achaete-scute complex homolog 1 (Drosophila) (ASCL1)
  • achaete-scute complex homolog 1 (LOC100220505)
  • achaete-scute complex homolog 1 (ascl1)
  • achaete-scute complex homolog 1 (Drosophila) (Ascl1)
  • achaete-scute complex homolog 2 (Drosophila) (ASCL2)
  • achaete-scute homolog 1-like (LOC100342114)
  • ash1 (absent, small, or homeotic)-like (Drosophila) (ASH1L)
  • AI225900 protein
  • ASCL1 protein
  • ascl1-A protein
  • ASH1 protein
  • ASH1L1 protein
  • bHLHa46 protein
  • HASH1 protein
  • KMT2H protein
  • MASH1 protein
  • Xash1 protein

Protein level used designations for ASCL1

achaete-scute complex homolog 1 (Drosophila) , achaete-scute complex-like 1 , achaete-scute homolog 1 , ASH-1 , achaete scute protein , class A basic helix-loop-helix protein 46 , achaete-scute complex homolog-like 1 , mASH-1 , mammalian achaete scute homolog 1 , achaete-scute complex homolog 1 , achaete-scute homolog 2 , transcription factor cash4 , ASH1-like protein , absent small and homeotic disks protein 1 homolog , histone-lysine N-methyltransferase ASH1L , lysine N-methyltransferase 2H , probable histone-lysine N-methyltransferase ASH1L

GENE ID SPECIES
698820 Macaca mulatta
100220505 Taeniopygia guttata
378517 Xenopus laevis
429 Homo sapiens
482628 Canis lupus familiaris
540473 Bos taurus
17172 Mus musculus
64186 Rattus norvegicus
386573 Gallus gallus
100734843 Cavia porcellus
395791 Gallus gallus
100342114 Oryctolagus cuniculus
55870 Homo sapiens
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