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Acid Phosphatase 2, Lysosomal Proteins (ACP2)

ACP2 encodes the beta subunit of lysosomal acid phosphatase (LAP). Additionally we are shipping ACP2 Antibodies (27) and ACP2 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACP2 53 P11117
ACP2 11432 P24638
Rat ACP2 ACP2 24162  
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Top ACP2 Proteins at antibodies-online.com

Showing 7 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 9 to 11 Days
$484.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ACP2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, ,
Mouse (Murine) ,
,

More Proteins for Acid Phosphatase 2, Lysosomal (ACP2) Interaction Partners

Human Acid Phosphatase 2, Lysosomal (ACP2) interaction partners

  1. An enzymatically inactive allel (show SCN7A Proteins)e of mouse Acp2 causes cerebellum abnormalities, growth retardation, hair-follicle abnormalities, and an ataxia-like phenotype.

Mouse (Murine) Acid Phosphatase 2, Lysosomal (ACP2) interaction partners

  1. ACP2 has critical roles in the development of the anterior cerebellum and it may regulate anterior and central zone compartmentation.

  2. These data suggest that ACP2 expression is dynamically regulated during development, and in the adult, it may function within a complex architecture that is linked to cerebellar modular organization.

  3. dephosphorylation of Man6P-containing lysosomal proteins requires the concerted action of Acp2 and Acp5 (show ACP5 Proteins) and is needed for hydrolysis and removal of degradation products

  4. Acp2 is the gene mutated in nax (show SCN7A Proteins) mice provides a valuable model system for studying the role of Acp2 in cerebellum and skin homeostasis.

  5. The data suggest that lysosomal dysfunction and accumulation of storage material require increased biogenesis of LAP/ACP2 and LAMP-2 (show LAMP2 Proteins) positive membranes which makes LAP/ACP2 suitable as biomarker of Batten disease.

ACP2 Protein Profile

Protein Summary

This gene encodes the beta subunit of lysosomal acid phosphatase (LAP). LAP is chemically and genetically distinct from red cell acid phosphatase. The encoded protein belongs to a family of distinct isoenzymes which hydrolyze orthophosphoric monoesters to alcohol and phosphate. Mutations in this gene or in the related alpha subunit gene cause acid phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with ACP2

  • acid phosphatase 2, lysosomal (ACP2)
  • acid phosphatase 2, lysosomal (acp2)
  • acid phosphatase 2, lysosomal (LOC100224806)
  • acid phosphatase 2, lysosomal (LOC100352644)
  • acid phosphatase 2, lysosomal (Acp2)
  • Acp-2 protein
  • ACP2 protein
  • LAP protein

Protein level used designations for ACP2

lysosomal acid phosphatase , lysosomal acid phosphatase 2 , acid phosphatase 2, lysosomal , LAP , Acid phosphatase 2, lysozymal , LMW-PTP-II low molecular weight phosphotyrosine protein phosphatase isozyme 2

GENE ID SPECIES
428864 Gallus gallus
451166 Pan troglodytes
713744 Macaca mulatta
779653 Xenopus (Silurana) tropicalis
100057910 Equus caballus
100224806 Taeniopygia guttata
100352644 Oryctolagus cuniculus
53 Homo sapiens
475983 Canis lupus familiaris
535407 Bos taurus
11432 Mus musculus
24162 Rattus norvegicus
100158274 Xenopus laevis
100174154 Pongo abelii
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