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anti-Aconitase 1 (ACO1) Antibodies

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity). Additionally we are shipping Aconitase 1 Proteins (15) and Aconitase 1 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACO1 11428 P28271
ACO1    
ACO1    
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Top anti-Aconitase 1 Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ICC, IF, WB WB Image Aconitase 1 antibody detects Aconitase 1 protein by western blot analysis. A. 30 μg 293T whole cell lysate/extract B. 30 μg HeLa whole cell lysate/extract C. 30 μg HepG2 whole cell lysate/extract 7.5 % SDS-PAGE Aconitase 1 antibody , dilution: 1:1000 ICC/IF Image Aconitase 1 antibody [N1C1] detects Aconitase 1 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: Aconitase 1 protein stained by Aconitase 1 antibody [N1C1] , diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 μm. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Human Rabbit Un-conjugated IC, IF, IHC, WB   200 μL Log in to see 9 Days
$487.50
Details
Chicken Rabbit Un-conjugated IHC, WB   200 μL Log in to see 9 Days
$575.00
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

ACO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,
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Human ,
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Rat (Rattus) ,
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More Antibodies against Aconitase 1 Interaction Partners

Mouse (Murine) Aconitase 1 (ACO1) interaction partners

  1. The Irp1-/- mice develop polycythemia and pulmonary hypertension, and suggesting that Irp1 plays an essential role in erythropoiesis and in the pulmonary and cardiovascular systems.

  2. IRP1 and IRP2 (show IREB2 Antibodies) mutant mice rapidly succumb to systemic infection with Salmonella Typhimurium, a pathogenic bacterium that multiplies within macrophages, with increased bacterial burdens in liver and spleen.

  3. results uncover an unexpected protective role of IRP1 in pathological conditions associated with altered Fe-S metabolism

  4. Aco1 KD in fully differentiated 3T3-L1 adipocytes decreased lipogenic, Idh1 (show IDH1 Antibodies), Adipoq (show ADIPOQ Antibodies), and Glut4 (show SLC2A4 Antibodies) gene expression.

  5. impaired mitochondrial [Fe-S] cluster biogenesis in Mfrn1 (show SLC25A37 Antibodies)(gt/gt (show FABP6 Antibodies)) cells results in elevated IRP1 RNA-binding that attenuates ALAS2 (show ALAS2 Antibodies) mRNA translation and protoporphyrin accumulation

  6. Data indicate that JTR-009, a benzimidazole, operated by preventing iron-regulatory protein-1 (IRP1) from binding to the iron-responsive element (IRE) in APP (show APP Antibodies) mRNA.

  7. Human ACO1 is a moonlighting protein that has both aconitase (show ACO2 Antibodies) enzyme activity as well as an mRNA binding function.

  8. Aco1 is a moonlighting protein that has aconitase (show ACO2 Antibodies) activity as well as mRNA binding ability.

  9. IRP1 is the principal regulator of HIF2alpha (show EPAS1 Antibodies) mRNA translation

  10. Irp1 deletion enhanced HIF2alpha (show EPAS1 Antibodies) protein expression in kidneys of Irp1(-/-) mice.

Aconitase 1 (ACO1) Antigen Profile

Protein Summary

Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity). Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes RNA binding (By similarity).

Gene names and symbols associated with anti-Aconitase 1 (ACO1) Antibodies

  • aconitase 1 (Aco1) antibody
  • Aco-1 antibody
  • AI256519 antibody
  • Irebp antibody
  • Irp1 antibody

Protein level used designations for anti-Aconitase 1 (ACO1) Antibodies

IRE-BP 1 , citrate hydro-lyase , cytoplasmic aconitase , cytoplasmic aconitate hydratase , iron regulatory protein 1 , iron-responsive element-binding protein 1

GENE ID SPECIES
11428 Mus musculus
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