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Actin, gamma 2, Smooth Muscle, Enteric Proteins (ACTG2)

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Additionally we are shipping ACTG2 Antibodies (58) and ACTG2 Kits (28) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ACTG2 25365 P63269
ACTG2 72 P63267
ACTG2 11468 P63268
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Top ACTG2 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,026.83
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,026.83
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,026.83
Details

ACTG2 Proteins by Origin and Source

Origin Expressed in Conjugate
Rat (Rattus)

Human ,
,
Mouse (Murine)

More Proteins for Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) Interaction Partners

Rabbit Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) interaction partners

  1. TnT has a previously unrecognized role in forming the inactive state of regulated actin.

  2. The terminal pointed end subunit is tilted (show OTOP1 Proteins) towards the penultimate subunit, allowing specific and extra loop-to-loop inter-strand contacts between the two end subunits, which is not possible in other parts of the filament.

  3. There was no significant change in the expression of TGF-beta(2 (show TGFB2 Proteins)) and alpha-SMA (show SMN1 Proteins) after laser-assisted intrastromal scanning.

  4. The arrangement of actin subunits in an actin dimer assembled by tandem W domains resembles that of a long-pitch helix of the actin filament.

  5. The distribution of laminin and alphaSMA (show ACTA2 Proteins) in the testis and epididymis might point out to their roles in the male reproduction.

Human Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) interaction partners

  1. ACTG2 is expressed in a fraction of small intestinal neuroendocrine tumors, can inhibit cell growth in vitro, and is positively regulated by miR (show MLXIP Proteins)-145.

  2. Mutations within ACTG2 are associated with fetal megacystis in microcolon intestinal hypoperistalsis syndrome.

  3. Phenotypic spectrum of ACTG2 missense variants involved severe pathology in multiple smooth muscle-dependent organs including the biliary tract and the uterus in the family with visceral myopathy.

  4. gammaSMA expression in hepatocellular carcinoma is strongly correlated with the EMT (show ITK Proteins) process, HCC (show FAM126A Proteins) aggressiveness and the identification of cancer stem cells

  5. ACTG2 encodes g2 enteric actin and is the first gene to be clearly associated with Megacystis-microcolon-intestinal hypoperistalsis syndrome, suggesting an important role for contractile proteins in enteric smooth muscle disease.

  6. Two novel mutations in the ACTG2 gene, p.R178L and p.R178C, have been identified in two unrelated children with congenital distended bladder, microcolon, and intestinal hypoperistalsis (MMIHS).

  7. The R148S variant in ACTG2 as a cause of autosomal dominant familial visceral myopathy in one family.

  8. NOX4 (show NOX4 Proteins) and ROS (show ROS1 Proteins) have a role in myofibroblast differentiation and collagen and alpha-actin (show ACTA2 Proteins) production of TGF- beta1 (show TGFB1 Proteins)-induced nasal polyp-derived fibroblasts.

  9. SMGA (show SAMD4A Proteins) gene activity in prostate epithelia is due, in part, to the androgen-dependent expression of Nkx 3.1 (show NKX3-1 Proteins)

  10. RNA polymerase II accumulates in the promoter-proximal region of the dihydrofolate reductase (show DHFR Proteins) and gamma-actin (show ACTG1 Proteins) genes.

Mouse (Murine) Actin, gamma 2, Smooth Muscle, Enteric (ACTG2) interaction partners

  1. MYOCD can discriminate among several juxtaposed CArG elements, presumably through its novel partnership with NKX3.1 (show NKX3-1 Proteins), to optimally transactivate the human ACTG2 promoter

ACTG2 Protein Profile

Protein Summary

Actins are highly conserved proteins that are involved in various types of cell motility and in the maintenance of the cytoskeleton. Three types of actins, alpha, beta and gamma, have been identified in vertebrates. Alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. This gene encodes actin gamma 2\; a smooth muscle actin found in enteric tissues. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Based on similarity to peptide cleavage of related actins, the mature protein of this gene is formed by removal of two N-terminal peptides.

Gene names and symbols associated with ACTG2

  • actin, gamma 2, smooth muscle, enteric (ACTG2)
  • actin, alpha 2, smooth muscle, aorta (ACTA2)
  • actin, gamma 2, smooth muscle, enteric (Actg2)
  • ACT protein
  • Act-4 protein
  • Act4 protein
  • ACTA3 protein
  • ACTE protein
  • ACTG2 protein
  • ACTGE protein
  • ACTL3 protein
  • ACTSG protein
  • GAMMA-ACTIN protein
  • SMGA protein

Protein level used designations for ACTG2

actin, gamma 2, smooth muscle, enteric , actin, gamma-enteric smooth muscle-like , actin, gamma 2 propeptide-like , actin, aortic smooth muscle , alpha-actin-2 , alpha-smooth muscle actin , actin, gamma-enteric smooth muscle , alpha-actin-3 , gamma-2-actin , gamma-enteric smooth muscle actin , smooth muscle gamma-actin , actin-like protein , alpha-actin 3 , smooth muscle gamma actin

GENE ID SPECIES
475792 Canis lupus familiaris
707447 Macaca mulatta
739500 Pan troglodytes
100057561 Equus caballus
100404219 Callithrix jacchus
100350318 Oryctolagus cuniculus
100581173 Nomascus leucogenys
100009271 Oryctolagus cuniculus
25365 Rattus norvegicus
72 Homo sapiens
11468 Mus musculus
281595 Bos taurus
396084 Gallus gallus
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