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ATF3 encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Additionally we are shipping ATF3 Kits (35) and ATF3 Proteins (9) and many more products for this protein.
Showing 10 out of 124 products:
Human Monoclonal ATF3 Primary Antibody for WB - ABIN394440
Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010
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Human Polyclonal ATF3 Primary Antibody for IF (p), IHC (p) - ABIN669561
Hu, Li, Li: MARVELD1 Inhibits Nonsense-Mediated RNA Decay by Repressing Serine Phosphorylation of UPF1. in PLoS ONE 2013
Show all 4 references for ABIN669561
Human Polyclonal ATF3 Primary Antibody for EIA, WB - ABIN950549
Lee, Bahn, Whitlock, Baek: Activating transcription factor 2 (ATF2) controls tolfenamic acid-induced ATF3 expression via MAP kinase pathways. in Oncogene 2010
Show all 2 references for ABIN950549
Human Polyclonal ATF3 Primary Antibody for IP - ABIN336138
Wagner, Green: HTLV-I Tax protein stimulation of DNA binding of bZIP proteins by enhancing dimerization. in Science (New York, N.Y.) 1993
Human Polyclonal ATF3 Primary Antibody for FACS, WB - ABIN1536715
Mo, Dai, Kang, Cui, He et al.: Ectopic expression of human MutS homologue 2 on renal carcinoma cells is induced by oxidative stress with interleukin-18 promotion via p38 mitogen-activated protein kinase (MAPK) and c-Jun N-terminal ... in The Journal of biological chemistry 2012
Chicken Polyclonal ATF3 Primary Antibody for WB - ABIN2774825
Beleza-Meireles, Töhönen, Söderhäll, Schwentner, Radmayr, Kockum, Nordenskjöld: Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias. in European journal of endocrinology / European Federation of Endocrine Societies 2008
Data show that Atf3 was detected in retinal ganglion cell axons in both the nerve fiber layer and the optic nerve on the injured side.
Data show that ATF3 may be an important mediator of optic nerve regeneration-promoting gene expression in fish, a role which merits further investigation.
CARMA1 (show CARD11 Antibodies)- and MyD88 (show MYD88 Antibodies)-dependent activation of Jun (show JUN Antibodies)/ATF-type AP-1 (show FOSB Antibodies) complexes is a hallmark of ABC (show ABCB6 Antibodies) diffuse large B-cell lymphomas.
Activating transcription factor 3 represses inflammatory responses by binding to the p65 (show GORASP1 Antibodies) subunit of NF-kappaB (show NFKB1 Antibodies)
TGRL lipolysis products induce stress protein ATF3 via the TGF-beta (show TGFB1 Antibodies) receptor pathway, resulting in induction of apoptosis in aortic endothelial cells
ATF3 regulates canonical TGFbeta and Smad signaling and fibroblast (show TGFB1 Antibodies)activation in systemic sclerosis.
ATF3 overexpression leads to an increase of collective cell invasion phenotype in Colorectal Cancer.
Data suggest that after the expression of activating transcription factor 3 (ATF3) and microRNA miR (show MLXIP Antibodies)-30c-2-3p elicited by lysophosphatidic acid, miR (show MLXIP Antibodies)-30c-2-3p negatively regulates the expression of ATF3 through post-transcriptional silencing.
Taken together, these results suggest that ATF3 promotes the progression of human gliomas
DNA damage-triggered ATF3 controlled p53 (show TP53 Antibodies) accumulation and generation of double-strand breaks may serve as a switch between DNA damage and cell death following TOP2A (show TOP2A Antibodies) inhibitor treatment.
The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60 (show KAT5 Antibodies) stability by promoting USP7 (show USP7 Antibodies)-mediated deubiquitination of Tip60 (show KAT5 Antibodies).
ATF3 is inactive in healthy hepatic cells and activated following hepatitis C virus infection.
Activating transcription factor 3 represses inflammatory responses by binding to the p65 (show NFkBP65 Antibodies) subunit of NF-kappaB (show NFKB1 Antibodies)
Knockout of the ATF3 gene reduced the stimulatory effect of TGFbeta (show TGFB1 Antibodies) on fibroblasts by interfering with canonical Smad (show SMAD1 Antibodies) signalling and protected the mice from experimental fibrosis in two different models.
ATF3 is a key regulator in cardiac hypertrophy through a cross-talk between cardiomyocytes and macrophages.
Data show that activating transcription factor 3 (ATF3) acted as a transcriptional repressor and regulated interferon-beta (IFN-beta (show IFNB1 Antibodies)) via direct binding to a regulatory site distal to the Ifnb1 (show IFNB1 Antibodies) promoter.
ATF3 binds to carboxyl-terminal modulator protein (show THEM4 Antibodies) and suppresses its transcription following brain ischemia.
Involvement of ATF3 in the negative regulation of iNOS (show NOS2 Antibodies) expression and NO production in activated macrophages
ATF3 suppresses fibrosis early but not late during infarct-induced heart failure. Although ATF3 deficiency was associated with more fibrosis, this did not occur at the expense of survival, which was higher in the ATF3-null mice.
these results demonstrate that during acute inflammation Atf3 negatively regulates Ptgs2 (show PTGS2 Antibodies)
results thus link ATF3 to the AKT (show AKT1 Antibodies) signaling, and suggest that ATF3 is a tumor suppressor for the major subset of prostate cancers harboring dysfunctional Pten (show PTEN Antibodies)
ATF3 confers protection to lung injury by preventing inflammatory cell recruitment and barrier disruption in a cell-specific manner, ATF3 deletion releases Nrf2 (show NFE2L2 Antibodies) from ATF3-mediated transcriptional inhibition; however, absence of ATF3 results in Nrf2 (show NFE2L2 Antibodies) proteasomal degradation.
ATF3 appears to affect gonadotropin-stimulated progesterone secretion at a step or steps downstream of PKA signaling and before cholesterol conversion to progesterone.
ATF3 induction by acute hypoxia is mediated by nitric oxide and the JNK (show MAPK8 Antibodies) pathway in endothelial cells
Data indicate increasing expression for CREB (show CREB1 Antibodies), ATF1 (show AFT1 Antibodies), and ATF3 during gastrulation.
chromosome mapping of UCK2 (show UCK2 Antibodies), ATF3 and RGS18 (show RGS18 Antibodies) by radiation hybrid mapping. (UCK2 (show UCK2 Antibodies) AND ATF3 AND RGS18 (show RGS18 Antibodies))
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
cyclic AMP-dependent transcription factor ATF-3
, activating transcription factor 3
, cAMP-dependent transcription factor ATF-3
, transcription factor LRG-21
, liver regeneration factor 1