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Over-expression of atf4 in embryos interferes with neurogenesis and eye formation.
Unlike other CREB2 (ATF4) proteins, the ATF4 isolated from the gonads of Xenopus embryos contains a consensus phosphorylation site for protein kinase A (PKA).
expression levels of porcine ATF4 gene were up-regulated 60 days and 120 days after birth in both breeds and the expression level in Meishan pigs was obviously higher than that in Large White pigs
Tissue transcription analysis revealed that both porcine CREB2 (show ATF2 ELISA Kits) and CREB3 (show CREB3 ELISA Kits) mRNA were ubiquitously detected in all examined tissues.
Transcriptional activator. Binds the cAMP response present in many viral and cellular promoters (By similarity).
activating transcription factor 4 (tax-responsive enhancer element B67)
, activating transcription factor ATF-4
, cAMP-dependent transcription factor ATF-4
, cyclic AMP-dependent transcription factor ATF-4
, activating transcription factor 4C
, activating transcription factor 4
, cAMP response element-binding protein 2