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anti-Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) Antibodies

ATF4 encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. Additionally we are shipping ATF4 Kits (32) and ATF4 Proteins (16) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATF4 468 P18848
ATF4 11911 Q06507
ATF4 79255 Q9ES19
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Top anti-ATF4 Antibodies at antibodies-online.com

Showing 10 out of 270 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated IHC, WB WB Suggested Anti-ATF4 Antibody Titration: 0.125ug/mlELISA Titer: 1:62500Positive Control: NIH/3T3 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ATF4 Antibody Titration: 5.0ug/mlELISA Titer: 1:62500Positive Control: Jurkat cell lysate WB Suggested Anti-ATF4  Antibody Titration: 5.0 µg/mL ELISA Titer: 1:.2500  Positive Control: Jurkat cell lysate  ATF4 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ATF4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human Muscle Host: Rabbit  Target Name: ATF4  Sample Tissue: Human Adult Placenta  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN184656 staining (1µg/ml) of Raji lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB ATF4 Antibody (Center) (ABIN656176) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the ATF4 antibody detected the ATF4 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, WB ATF4 Antibody (Center) western blot analysis in MDA-MB435 cell line lysates (35µg/lane).This demonstrates the ATF4 antibody detected the ATF4 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of ATF4 (arrow) using rabbit anti-ATF4 Antibody (S245) (ABIN390250). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ATF4 gene (Lane 2) (Origene Technologies). Western blot analysis of ATF4 Antibody (S245) Pab (ABIN390250) pre-incubated without(lane 1) and with(lane 2) blocking peptide in WiDr cell line lysate. ATF4 Antibody (pS245) (arrow) was detected using the purified polyclonal antibody (1:60/250 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to ATF4 on HeLa cell (antibody concentration 10 µg/mL). ATF4 monoclonal antibody (M01), clone 2B3 Western Blot analysis of ATF4 expression in NIH/3T3. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

ATF4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ATF4 Antibodies

  1. Human Monoclonal ATF4 Primary Antibody for IF, WB - ABIN394112 : Liew, Bochenski, Kawamori, Hu, Leech, Wanic, Malecki, Warram, Qi, Krolewski, Kulkarni: The pseudokinase tribbles homolog 3 interacts with ATF4 to negatively regulate insulin exocytosis in human and mouse beta cells. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 references for ABIN394112

  2. Human Polyclonal ATF4 Primary Antibody for EIA, WB - ABIN950550 : Dey, Baird, Zhou, Palam, Spandau, Wek: Both transcriptional regulation and translational control of ATF4 are central to the integrated stress response. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN950550

  3. Human Polyclonal ATF4 Primary Antibody for WB - ABIN656176 : Frank, Ge, Xie, Zhou, Tsai: Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for ABIN656176

  4. Mouse (Murine) Polyclonal ATF4 Primary Antibody for IHC, WB - ABIN2779918 : Smith, Schmechel, Raghavan, Abelson, Reilly, Katze, Kaufman, Bohjanen, Schiff: Reovirus induces and benefits from an integrated cellular stress response. in Journal of virology 2006 (PubMed)
    Show all 4 references for ABIN2779918

  5. Human Polyclonal ATF4 Primary Antibody for EIA, WB - ABIN358807 : Gombart, Grewal, Koeffler: ATF4 differentially regulates transcriptional activation of myeloid-specific genes by C/EBPepsilon and C/EBPalpha. in Journal of leukocyte biology 2007 (PubMed)
    Show all 4 references for ABIN358807

  6. Human Polyclonal ATF4 Primary Antibody for EIA, WB - ABIN374137 : Tsujimoto, Nyunoya, Morita, Sato, Shimotohno: Isolation of cDNAs for DNA-binding proteins which specifically bind to a tax-responsive enhancer element in the long terminal repeat of human T-cell leukemia virus type I. in Journal of virology 1991 (PubMed)
    Show all 2 references for ABIN374137

  7. Cow (Bovine) Polyclonal ATF4 Primary Antibody for WB - ABIN2780378 : Lassot, Estrabaud, Emiliani, Benkirane, Benarous, Margottin-Goguet: p300 modulates ATF4 stability and transcriptional activity independently of its acetyltransferase domain. in The Journal of biological chemistry 2005 (PubMed)

  8. Human Polyclonal ATF4 Primary Antibody for WB - ABIN390250 : Marchand, Tomkiewicz, Magne, Barouki, Garlatti: Endoplasmic reticulum stress induction of insulin-like growth factor-binding protein-1 involves ATF4. in The Journal of biological chemistry 2006 (PubMed)

  9. Human Polyclonal ATF4 Primary Antibody for WB - ABIN2792651 : Zhou, Palam, Jiang, Narasimhan, Staschke, Wek: Phosphorylation of eIF2 directs ATF5 translational control in response to diverse stress conditions. in The Journal of biological chemistry 2008 (PubMed)

More Antibodies against ATF4 Interaction Partners

Xenopus laevis Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) interaction partners

  1. Over-expression of atf4 in embryos interferes with neurogenesis and eye formation.

  2. Unlike other CREB2 (ATF4) proteins, the ATF4 isolated from the gonads of Xenopus embryos contains a consensus phosphorylation site for protein kinase A (PKA).

Human Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) interaction partners

  1. Inhibition or overexpression of ATF4 confirms the role of ATF4 in SESN2 (show SESN2 Antibodies) gene up-regulation induced by mitochondrial dysfunction.

  2. ATF4 and ATF6beta (show ATF6B Antibodies) act synergistically in the negative regulation of placental growth factor (show PGF Antibodies) mRNA expression

  3. Authors observed that a slow rate of ATF4-translation and late re-initiation of general translation coincided with cells which were resistant to ER stress-induced cell death.

  4. a reduction of cell death was associated with decreased levels of ATF4 in a rhabdomyosarcoma cell line

  5. Combined administration inhibited the cells most potently and time-dependently, decreased the expression of HO-1 (show HMOX1 Antibodies), and significantly increased the expression of ATF4, CHOP (show DDIT3 Antibodies), and Ire-1 (show ERN1 Antibodies) proteins expression levels

  6. Global profiling in human mesenchymal stem cells and a novel cell-free assay reveals that ATF4 requires C/EBPbeta (show CEBPB Antibodies) for genomic binding at a motif distinct from that bound by the C/EBPbeta (show CEBPB Antibodies) homodimer.

  7. This study outlines the mechanism of NIR (show NOC2L Antibodies) laser phototoxicity and the utility of monitoring surface temperature and ATF4 expression as potential biomarkers to develop safe and effective clinical applications.

  8. Up-regulation of ATF4 is associated with Pancreatic Neuroendocrine Tumors.

  9. The ATF4/p75NTR (show NGFR Antibodies)/IL-8 (show IL8 Antibodies) signal pathway may have an important role in EndoMT induced by SFO.

  10. ATF4 is a potential biomarker for esophageal squamous cell carcinoma (ESCC) prognosis and its dysregulation may play a key role in the regulation of invasion and metastasis in ESCC.

Mouse (Murine) Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) interaction partners

  1. TFEB (show TFEB Antibodies)-regulated signaling pathway for osteoblast differentiation is involved in ATF4/CHOP (show DDIT3 Antibodies)-dependent signaling pathway.

  2. These findings identify C/EBPgamma (show CEBPG Antibodies) as a novel antioxidant regulator and an obligatory ATF4 partner that controls redox homeostasis in normal and cancerous cells.

  3. Gcn2 (show EIF2AK4 Antibodies) & Atf4 are involved in L-proline metabolism regulation in embryonic stem cells.

  4. This study outlines the mechanism of NIR (show NOC2L Antibodies) laser phototoxicity and the utility of monitoring surface temperature and ATF4 expression as potential biomarkers to develop safe and effective clinical applications.

  5. ATF4 plays a pivotal role in functional expansion and repopulating efficiency of HSCs in developing FL

  6. results identify ursolic acid and tomatidine as potential agents and/or lead compounds for reducing ATF4 activity, weakness, and atrophy in aged skeletal muscle

  7. The CARE-LUC mouse model represents an innovative tool to investigate the eIF2alpha (show EIF2A Antibodies)-ATF4 axis and to develop drugs targeting this important pathway in the remediation of related pathologies.

  8. exogenous overexpression of ATF4 in breast cancer cells may facilitate the recruitment of macrophages into tumor tissues and promote tumor angiogenesis and tumor growth indirectly.

  9. We conclude that ATF4 is a key regulator of the physiological state necessary for neuronal plasticity and memory.

  10. Elevation of ATF4, at least in liver, thus seems to be a shared feature of diets, drugs, genes, and developmental alterations that extend maximum lifespan in mice.

Pig (Porcine) Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) interaction partners

  1. expression levels of porcine ATF4 gene were up-regulated 60 days and 120 days after birth in both breeds and the expression level in Meishan pigs was obviously higher than that in Large White pigs

  2. Tissue transcription analysis revealed that both porcine CREB2 (show ATF2 Antibodies) and CREB3 (show CREB3 Antibodies) mRNA were ubiquitously detected in all examined tissues.

ATF4 Antigen Profile

Protein Summary

This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

Gene names and symbols associated with ATF4

  • activating transcription factor 4 (tax-responsive enhancer element B67) (ATF4) antibody
  • activating transcription factor 4 (atf4-a) antibody
  • activating transcription factor 4b1 (tax-responsive enhancer element B67) (atf4b1) antibody
  • activating transcription factor 4 (atf4) antibody
  • activating transcription factor 4b2 (atf4b2) antibody
  • activating transcription factor 4 (ATF4) antibody
  • activating transcription factor 4 (Atf4) antibody
  • Atf-4 antibody
  • ATF4 antibody
  • ATF4C antibody
  • C/ATF antibody
  • CREB-2 antibody
  • CREB2 antibody
  • sb:eu681 antibody
  • TAXREB67 antibody
  • TXREB antibody
  • wu:fb08f07 antibody
  • wu:fj01c08 antibody
  • wu:fk30b04 antibody
  • zgc:85951 antibody
  • zgc:171702 antibody

Protein level used designations for ATF4

cyclic AMP-dependent transcription factor ATF-4 , activating transcription factor 4 (tax-responsive enhancer element B67) , cAMP-dependent transcription factor ATF-4 , activating transcription factor 4C , activating transcription factor 4 , DNA-binding protein TAXREB67 , cAMP response element-binding protein 2 , cAMP-responsive element-binding protein 2 , cyclic AMP-responsive element-binding protein 2 , tax-responsive enhancer element B67 , tax-responsive enhancer element-binding protein 67 , c/EBP-related ATF , tax-responsive enhancer element-binding protein 67 homolog , taxREB67 homolog , activating transcription factor ATF-4 , rATF-4

GENE ID SPECIES
395693 Gallus gallus
398804 Xenopus laevis
406514 Danio rerio
448005 Xenopus (Silurana) tropicalis
468334 Pan troglodytes
556410 Danio rerio
703965 Macaca mulatta
744513 Pan troglodytes
100216465 Ovis aries
468 Homo sapiens
11911 Mus musculus
79255 Rattus norvegicus
100732296 Cavia porcellus
474503 Canis lupus familiaris
100144302 Sus scrofa
509107 Bos taurus
Selected quality suppliers for anti-ATF4 (ATF4) Antibodies
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