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anti-Activating Transcription Factor 6 (ATF6) Antibodies

ATF6 encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Additionally we are shipping ATF6 Kits (30) and ATF6 Proteins (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATF6 22926 P18850
ATF6 226641  
ATF6 304962  
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Top anti-ATF6 Antibodies at antibodies-online.com

Showing 10 out of 164 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ATF6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB AP17892PU-N ATF6 Antibody (Center) staining of Formalin-Fixed and Paraffin-Embedded Human brain tissue. This antibody was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. AP17892PU-N ATF6 Antibody (Center) staining of A2058 cell line lysates (35ug/lane) in Western blot analysis. ATF6 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of ATF6 Antibody (Center) (ABIN652625) in A2058 cell line lysates (35 µg/lane). ATF6 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with ATF6 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of rat kidney tissue lysis using ATF6 antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-ATF6 Polyclonal Antibody, Unconjugated (ABIN732293) at 1:200 followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain labeled with Anti-ATF6 Polyclonal Antibody, unconjugated (ABIN732293) followed by incubation with conjugated secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemical staining of MCF7 cells using AP30088PU-N ATF6 antibody at 10 μg/ml. Immunofluorescence of ATF6 in MCF7 cells with this product atF6 antibody at 10 µg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of ATF6 in A20 with this product atF6 antibody at 10 μg/ml. Western blot analysis of ATF6 in MDA-MB-361 cell lysate with this product atF6 antibody at (A) 0.5 and (B) 1 µg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated IP, WB 50 μg Log in to see 7 to 8 Days
$401.50
Details
Human Mouse Un-conjugated IP, WB 100 μg Log in to see 7 to 8 Days
$518.10
Details
Hamster Mouse Un-conjugated FACS, IHC, WB ATF-6 mAb tested by Western blot. ATF-6 detection by Western blot. The analysis was performed using ATF-6 mAb and 10 µg 293 nuclear extract. A protein of approximately 90 kDa is detected. 100 μg Log in to see 1 to 2 Days
$466.67
Details

ATF6 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-ATF6 Antibodies

  1. Human Monoclonal ATF6 Primary Antibody for IP, WB - ABIN2451924 : Mori: Divest yourself of a preconceived idea: transcription factor ATF6 is not a soluble protein! in Molecular biology of the cell 2010 (PubMed)
    Show all 5 references for ABIN2451924

  2. Human Polyclonal ATF6 Primary Antibody for EIA, IF - ABIN499351 : Liu, Kaufman: The unfolded protein response. in Journal of cell science 2003 (PubMed)
    Show all 4 references for ABIN499351

  3. Human Polyclonal ATF6 Primary Antibody for EIA, IF - ABIN499353 : Haze, Yoshida, Yanagi, Yura, Mori: Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. in Molecular biology of the cell 1999 (PubMed)
    Show all 4 references for ABIN499353

  4. Human Monoclonal ATF6 Primary Antibody for IP, WB - ABIN2451923 : Yamamoto, Sato, Matsui, Sato, Okada, Yoshida, Harada, Mori: Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. in Developmental cell 2007 (PubMed)
    Show all 4 references for ABIN2451923

  5. Hamster Monoclonal ATF6 Primary Antibody for FACS, IHC - ABIN2668920 : Donati, Imbriano, Mantovani: Dynamic recruitment of transcription factors and epigenetic changes on the ER stress response gene promoters. in Nucleic acids research 2006 (PubMed)
    Show all 2 references for ABIN2668920

  6. Human Polyclonal ATF6 Primary Antibody for EIA, IHC (p) - ABIN453523 : Zhu, Johansen, Prywes: Interaction of ATF6 and serum response factor. in Molecular and cellular biology 1997 (PubMed)
    Show all 2 references for ABIN453523

  7. Human Polyclonal ATF6 Primary Antibody for FACS, IHC (p) - ABIN652625 : Lee, Jin, Kang, Kim, Guthrie, Sreevalsan, Lee, Safe: The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells. in Molecular cancer research : MCR 2014 (PubMed)
    Show all 2 references for ABIN652625

  8. Human Polyclonal ATF6 Primary Antibody for IF (p), IHC (p) - ABIN732293 : Jiang, Ren, Jiang, Wang, Zhang, Yin, Wang, Qi, Wang, Feng: Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model of amyotrophic lateral sclerosis. in Neuroscience 2014 (PubMed)

  9. Human Polyclonal ATF6 Primary Antibody for WB - ABIN1105462 : Thameem, Farook, Bogardus, Prochazka: Association of amino acid variants in the activating transcription factor 6 gene (ATF6) on 1q21-q23 with type 2 diabetes in Pima Indians. in Diabetes 2006 (PubMed)

  10. Human Polyclonal ATF6 Primary Antibody for WB - ABIN2777413 : Kerbiriou, Le Drévo, Férec, Trouvé: Coupling cystic fibrosis to endoplasmic reticulum stress: Differential role of Grp78 and ATF6. in Biochimica et biophysica acta 2007 (PubMed)

More Antibodies against ATF6 Interaction Partners

Human Activating Transcription Factor 6 (ATF6) interaction partners

  1. We found that HCS (show HLCS Antibodies) identified compounds which inhibited ATF6 nuclear translocation with high specificity, as confirmed by the luciferase reporter assay and western blot analysis

  2. results identify a role for DREAM silencing in the activation of ATF6 signaling, which promotes early neuroprotection in HD.

  3. Endoplasmic reticulum stress related factor ATF6 and caspase-12 (show CASP12 Antibodies) trigger apoptosis in neonatal hypoxic-ischemic encephalopathy.

  4. Defective podocyte insulin (show INS Antibodies) signaling through p85-XBP1 (show XBP1 Antibodies) promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.

  5. protein expression were significantly higher in the placentas of women with early and late SPE than in the control women, whereas there were no differences in ATF6 and Ire1 (show ERN1 Antibodies) mRNA and protein.

  6. autosomal recessive achromatopsia is caused by a frameshift mutation in ATF6 in this Pakistani family

  7. A crucial and unexpected role for ATF6A in human foveal development and cone function.

  8. ATF6 preferentially reduces the secretion and extracellular aggregation of destabilized, aggregation-prone variants of the amyloidogenic protein TTR (show TTR Antibodies), as compared to stable WT TTR (show TTR Antibodies) and nonamyloidogenic TTR (show TTR Antibodies) variants.

  9. The genetic variation in ATF6 is associated with pre-diabetes and has interactive effects with BMI on pre-diabetes in the Chinese Han population.

  10. Data show that silver nanoparticles induce activating transcription factor-6 (ATF-6) degradation, leading to activation of the NLRP-3 (show NLRP3 Antibodies) inflammasome and pyroptosis.

Mouse (Murine) Activating Transcription Factor 6 (ATF6) interaction partners

  1. Our results suggest that ATF6alpha plays an important role in neuronal survival after KA-induced excitotoxicity through the regulation of Ca(2 (show CA2 Antibodies)+) response and neuronal activity

  2. results identify a role for DREAM silencing in the activation of ATF6 signaling, which promotes early neuroprotection in HD.

  3. ATF6alpha regulates the expression of endoplasmic reticulum chaperones, C/EBP homologous protein (show DDIT3 Antibodies), and ER-associated degradation components

  4. ATF6 positively regulates chondrocyte hypertrophy and endochondral bone formation.

  5. Defective podocyte insulin (show INS Antibodies) signaling through p85 (show ECM1 Antibodies)-XBP1 (show XBP1 Antibodies) promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.

  6. alpha-syn inhibited processing of ATF6 directly through physical interactions and indirectly through restricted incorporation into COPII vesicles.

  7. DKK3 induces stem cell differentiation into smooth muscle lineage via ATF6 signaling and myocardin (show MYOCD Antibodies) expression.

  8. The findings reveal a novel critical role of ATF6 in regulating ER stress-mediated apoptosis in chondrocyte differentiation and the molecular mechanisms involved.

  9. data suggest ATF6alpha required for the arginine vasopressin (show AVP Antibodies) neuron system to maintain water balance under dehydration

  10. Atf6alpha is sufficient to induce the Lmf1 (show LMF1 Antibodies) promoter in the absence of ER stress, and this effect is mediated by the TM-responsive cis (show CISH Antibodies)-regulatory element

Cow (Bovine) Activating Transcription Factor 6 (ATF6) interaction partners

  1. Exposure of endothelial cells to VEGF (show VEGFA Antibodies), high glucose, or hydrogen peroxide up-regulated the XBP1 (show XBP1 Antibodies)/IRE1 alpha (show ERN1 Antibodies) and ATF6 arms of the unfolded protein response compared with untreated cells.

ATF6 Antigen Profile

Protein Summary

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.

Gene names and symbols associated with ATF6

  • activating transcription factor 6 (ATF6) antibody
  • activating transcription factor 6 (Atf6) antibody
  • activating transcription factor 6 (atf6) antibody
  • 9130025P16Rik antibody
  • 9630036G24 antibody
  • AA789574 antibody
  • ATF-6-like antibody
  • Atf6 antibody
  • ATF6A antibody
  • Atf6alpha antibody
  • ESTM49 antibody
  • GB16435 antibody

Protein level used designations for ATF6

activating transcription factor 6 , cyclic AMP-dependent transcription factor ATF-6 alpha-like , cAMP-dependent transcription factor ATF-6 alpha , cyclic AMP-dependent transcription factor ATF-6 alpha

GENE ID SPECIES
100051169 Equus caballus
412432 Apis mellifera
457461 Pan troglodytes
496056 Xenopus laevis
720056 Macaca mulatta
100122162 Nasonia vitripennis
100451142 Pongo abelii
22926 Homo sapiens
226641 Mus musculus
304962 Rattus norvegicus
100158076 Sus scrofa
530610 Bos taurus
100358536 Oryctolagus cuniculus
100730337 Cavia porcellus
488660 Canis lupus familiaris
424365 Gallus gallus
541606 Ovis aries
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