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Activating Transcription Factor 6 Proteins (ATF6)

ATF6 encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Additionally we are shipping ATF6 Antibodies (164) and ATF6 Kits (30) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATF6 22926 P18850
ATF6 226641  
Rat ATF6 ATF6 304962  
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Top ATF6 Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$774.40
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$952.01
Details

ATF6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,
,

More Proteins for Activating Transcription Factor 6 (ATF6) Interaction Partners

Human Activating Transcription Factor 6 (ATF6) interaction partners

  1. We found that HCS (show HLCS Proteins) identified compounds which inhibited ATF6 nuclear translocation with high specificity, as confirmed by the luciferase reporter assay and western blot analysis

  2. results identify a role for DREAM silencing in the activation of ATF6 signaling, which promotes early neuroprotection in HD.

  3. Endoplasmic reticulum stress related factor ATF6 and caspase-12 trigger apoptosis in neonatal hypoxic-ischemic encephalopathy.

  4. Defective podocyte insulin (show INS Proteins) signaling through p85-XBP1 (show XBP1 Proteins) promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.

  5. protein expression were significantly higher in the placentas of women with early and late SPE than in the control women, whereas there were no differences in ATF6 and Ire1 (show ERN1 Proteins) mRNA and protein.

  6. autosomal recessive achromatopsia is caused by a frameshift mutation in ATF6 in this Pakistani family

  7. A crucial and unexpected role for ATF6A in human foveal development and cone function.

  8. ATF6 preferentially reduces the secretion and extracellular aggregation of destabilized, aggregation-prone variants of the amyloidogenic protein TTR (show TTR Proteins), as compared to stable WT TTR (show TTR Proteins) and nonamyloidogenic TTR (show TTR Proteins) variants.

  9. The genetic variation in ATF6 is associated with pre-diabetes and has interactive effects with BMI on pre-diabetes in the Chinese Han population.

  10. Data show that silver nanoparticles induce activating transcription factor-6 (ATF-6) degradation, leading to activation of the NLRP-3 (show NLRP3 Proteins) inflammasome and pyroptosis.

Mouse (Murine) Activating Transcription Factor 6 (ATF6) interaction partners

  1. Our results suggest that ATF6alpha plays an important role in neuronal survival after KA-induced excitotoxicity through the regulation of Ca(2 (show CA2 Proteins)+) response and neuronal activity

  2. results identify a role for DREAM silencing in the activation of ATF6 signaling, which promotes early neuroprotection in HD.

  3. ATF6alpha regulates the expression of endoplasmic reticulum chaperones, C/EBP homologous protein (show DDIT3 Proteins), and ER-associated degradation components

  4. ATF6 positively regulates chondrocyte hypertrophy and endochondral bone formation.

  5. Defective podocyte insulin (show INS Proteins) signaling through p85 (show ECM1 Proteins)-XBP1 (show XBP1 Proteins) promotes ATF6-dependent maladaptive ER-stress response in diabetic nephropathy.

  6. alpha-syn inhibited processing of ATF6 directly through physical interactions and indirectly through restricted incorporation into COPII vesicles.

  7. DKK3 induces stem cell differentiation into smooth muscle lineage via ATF6 signaling and myocardin expression.

  8. The findings reveal a novel critical role of ATF6 in regulating ER stress-mediated apoptosis in chondrocyte differentiation and the molecular mechanisms involved.

  9. data suggest ATF6alpha required for the arginine vasopressin (show AVP Proteins) neuron system to maintain water balance under dehydration

  10. Atf6alpha is sufficient to induce the Lmf1 (show LMF1 Proteins) promoter in the absence of ER stress, and this effect is mediated by the TM-responsive cis (show CISH Proteins)-regulatory element

Cow (Bovine) Activating Transcription Factor 6 (ATF6) interaction partners

  1. Exposure of endothelial cells to VEGF (show VEGFA Proteins), high glucose, or hydrogen peroxide up-regulated the XBP1 (show XBP1 Proteins)/IRE1 alpha (show ERN1 Proteins) and ATF6 arms of the unfolded protein response compared with untreated cells.

ATF6 Protein Profile

Protein Summary

This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis.

Gene names and symbols associated with ATF6

  • activating transcription factor 6 (ATF6)
  • activating transcription factor 6 (Atf6)
  • activating transcription factor 6 (atf6)
  • 9130025P16Rik protein
  • 9630036G24 protein
  • AA789574 protein
  • ATF-6-like protein
  • Atf6 protein
  • ATF6A protein
  • Atf6alpha protein
  • ESTM49 protein
  • GB16435 protein

Protein level used designations for ATF6

activating transcription factor 6 , cyclic AMP-dependent transcription factor ATF-6 alpha-like , cAMP-dependent transcription factor ATF-6 alpha , cyclic AMP-dependent transcription factor ATF-6 alpha

GENE ID SPECIES
100051169 Equus caballus
412432 Apis mellifera
457461 Pan troglodytes
496056 Xenopus laevis
720056 Macaca mulatta
100122162 Nasonia vitripennis
100451142 Pongo abelii
22926 Homo sapiens
226641 Mus musculus
304962 Rattus norvegicus
100158076 Sus scrofa
530610 Bos taurus
100358536 Oryctolagus cuniculus
100730337 Cavia porcellus
488660 Canis lupus familiaris
424365 Gallus gallus
541606 Ovis aries
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