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Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Additionally we are shipping ATF7IP2 Kits (4) and ATF7IP2 Proteins (2) and many more products for this protein.
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Human Polyclonal ATF7IP2 Primary Antibody for FACS, IHC (p) - ABIN654466
Ichimura, Watanabe, Sakamoto, Aoto, Fujita, Nakao: Transcriptional repression and heterochromatin formation by MBD1 and MCAF/AM family proteins. in The Journal of biological chemistry 2005
These data suggest that MBD1 (show DPEP1 Antibodies).MCAF1 (show ATF7IP Antibodies).SETDB1 (show SETDB1 Antibodies) complex facilitates the formation of heterochromatic domains, emphasizing the role of MCAF (show CCL2 Antibodies)/AM family proteins in epigenetic control, and describe a new family member, MCAF2 (ATF7IP2).
cloning and characterization of PSM2; deduced protein has high similarity with human MCAF2; hypothesized that PSM2 might interact with some important partners by the conserved domain and be involved in the transcription modulation during gonad development
Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (By similarity).
ATF7-interacting protein 2
, MBD1-containing chromatin associated factor 2
, MBD1-containing chromatin-associated factor 2
, activating transcription factor 7-interacting protein 2
, protein similar to MCAF2