anti-Activin A Receptor, Type IIA (ACVR2A) Antibodies

ACVR2A encodes activin A type II receptor. Additionally we are shipping Activin Receptor Type IIA Proteins (37) and Activin Receptor Type IIA Kits (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACVR2A 92 P27037
ACVR2A 29263 P38444
ACVR2A 11480 P27038
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Top anti-Activin Receptor Type IIA Antibodies at antibodies-online.com

Showing 10 out of 113 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. (LEFT)Western blot analysis of anti-ACVR2A Antibody (N-term) in mouse liver brain and kidney tissue lysates (35ug/lane). ACVR2A (arrow) was detected using the purified Pab. (RIGHT)Western blot analysis of ACVR2A (arrow) using rabbit polyclonal ACVR2A Antibody 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ACVR2A Antibody (N-term) (ABIN391160) in mouse liver brain and kidney tissue lysates (35 µg/lane). ACVR2A (arrow) was detected using the purified polyclonal antibody. Western blot analysis of ACVR2A (arrow) using rabbit polyclonal ACVR2A Antibody (N-term) (ABIN391160). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the ACVR2A gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 0.2 mL Log in to see 11 to 13 Days
$542.85
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti ARIP2B Polyclonal Antibody, Unconjugated (ABIN728383) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1: mouse testis lysates Lane 2: mouse brain lysates probed with Anti ARIP2a Polyclonal Antibody, Unconjugated (ABIN728383) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 57kD. Observed band size: 57kD. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Cow Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$420.00
Details
Cow Rabbit Un-conjugated ICC, IHC, IP, WB 100 μg Log in to see 13 to 16 Days
$420.00
Details
Mouse Rabbit Un-conjugated WB Mouse Acvr2a Antibody (N-term)  western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Acvr2a antibody detected the Acvr2a protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB <b>Western blot</b> (WB) analyzes of ACTR-IIA antibody in extracts from rat kidney cells. 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Allophycocyanin FACS Detection of Activin RIIA in K562 Human Cell Line by Flow Cytometry. K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human Activin RIIA APC-conjugated Monoclonal Antibody. Detection of Activin RIIA in K562 Human Cell Line by Flow Cytometry. K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human Activin RIIA APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$357.00
Details

ACVR2A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Rat (Rattus)


Mouse (Murine)


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More Antibodies against Activin Receptor Type IIA Interaction Partners

Human Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. TGF-beta (show TGFB1 Antibodies) receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.(

  2. This locus harbors an evolutionary conserved gene-desert region with non-coding intergenic sequences likely involved in regulation of protein-coding flanking genes ZEB2 (show ZEB2 Antibodies) and ACVR2A. This region is intensively studied for mutations causing severe developmental/genetic disorders. Our analyses indicate a promising target region for interventions aimed to reduce risks of many major human diseases and mortality.

  3. Data suggest ALK1 (show ACVRL1 Antibodies) and ACVR2A/ACVR2B (show ACVR2B Antibodies), acting as BMP9 (show GDF2 Antibodies) co-receptors, rearrange pro-domains of BMP9 (show GDF2 Antibodies)--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  4. Activin A (show INHBA Antibodies) inhibited signaling by BMP-6 (show BMP6 Antibodies) and BMP-9 (show GDF2 Antibodies) by competing for type 2 receptors ACVR2A and ACVR2B (show ACVR2B Antibodies).

  5. Data suggest that an SNP in promoter region of ACVR2A (rs1424954, the pre-eclampsia susceptibility allele) down-regulates 1) expression of ACVR2A in trophoblasts and 2) signal transduction in response to excess activin-A (show INHBA Antibodies) (as seen in pre-eclampsia).

  6. Adenomyotic tissues express high levels of myostatin (show MSTN Antibodies), follistatin (show FST Antibodies), and activin (show Actbeta Antibodies) type II receptors.

  7. The gene ACVR2A was associated with the more severe early onset preeclampsia.

  8. For ACVR2A SNPs (rs10497025, rs1128919, rs13430086), no statistically significant difference was found between preeclampsia and control groups in terms of genotype and allele frequencies.

  9. ACVR2A was identified as a subnetwork component in functional association network analysis.

  10. ACVR2A showed statistically significant differential dose-expression relationship.

Cow (Bovine) Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. This genome-wide association study identified variants in the upstream region of ACVR2A, which were associated with female fertility in Japanese Black cattle.

Zebrafish Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. Roles in hindbrain and neural crest cell (NCC) patterning, in NCC derived pharyngeal arch cartilage and joint formation, and in tooth development.

Mouse (Murine) Activin A Receptor, Type IIA (ACVR2A) interaction partners

  1. Anti-ActRII blockade is an effective intervention against cancer cachexia providing benefit even in the presence of anti-cancer therapies.

  2. Data, including data from studies using transgenic mice, suggest that osteoblasts deficient in Acvr2A exhibit un-characteristic features; osteoclasts deficient in Acvr2A or Acvr2B (show ACVR2B Antibodies) or both appear normal. Acvr2A-deficient mice exhibit significantly increased femoral trabecular bone volume at 6 weeks of age; Acvr2B (show ACVR2B Antibodies)-deficient mice exhibit no significant change in any bone parameter.

  3. miR (show MLXIP Antibodies)-125b regulated the activin (show Actbeta Antibodies)/Smad2 (show SMAD2 Antibodies) signaling in neonatal mouse ovary by directly targeting the 3'-untranslated region of activin receptor type 2a

  4. Our study shows that a miR (show MLXIP Antibodies)-590/Acvr2a/Rad51b (show Rad51B Antibodies) signaling axis ensures the stabilization of mESCs by balancing DNA damage repair and rapid proliferation during self-renewal.

  5. Bmpr2 (show BMPR2 Antibodies) and Acvr2a normally play cell-type-specific, necessary roles in organelle biogenesis and the shutdown of developmental programs and cell division.

  6. Acvr2a is a Th17 specific gene making Th17 cells distinct from other helper T cells, Th1 (show HAND1 Antibodies), Th2, and Treg.

  7. stimulates expression of APRIL via the Smad3 (show SMAD3 Antibodies) and ERK (show EPHB2 Antibodies)/CREB (show CREB1 Antibodies) pathways in macrophages

  8. Results demonstrated that BMPRII (show BMPR2 Antibodies) and ActRII are the functional type II TGF-beta (show TGFB1 Antibodies) receptors in BMP-9 (show GDF2 Antibodies)-induced osteogenic differentiation of C3H10T1/2 cells.

  9. The coordinated activity of ActRIIA and BMPRII (show BMPR2 Antibodies) receptor subunits selectively mediates the chemotactic response to BMP7 (show BMP7 Antibodies).

  10. Activin (show Actbeta Antibodies) type IIB(ActRIIB (show ACVR2B Antibodies)) and its subfamily receptor, Activin (show Actbeta Antibodies) type IIA (ActRIIA), cooperatively mediate the Gdf11 (show GDF11 Antibodies) signal in patterning the axial vertebrae

Activin Receptor Type IIA (ACVR2A) Antigen Profile

Protein Summary

This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling\; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.

Gene names and symbols associated with ACVR2A

  • activin A receptor, type IIA (ACVR2A) antibody
  • activin A receptor, type IIA (acvr2a) antibody
  • activin A receptor, type IIA (LOC100224301) antibody
  • activin A receptor, type IIA (Acvr2a) antibody
  • activin A receptor, type IIAa (acvr2aa) antibody
  • activin receptor IIA (Acvr2a) antibody
  • actr2a antibody
  • ACTRII antibody
  • ActrIIa antibody
  • Acvr2 antibody
  • acvr2a antibody
  • rActR-II antibody
  • TactrII antibody
  • wu:fa02e10 antibody
  • XSTK9 antibody

Protein level used designations for ACVR2A

activin receptor IIA , activin receptor type-2A , activin A receptor, type IIA , ACTR-IIA , activin receptor type IIA , type II activin receptor , activin A receptor, type II , activin receptor, type IIA , ACTRIIA , activin receptor type II , activin type 2 receptor , activin receptor IIa , etID22865.9

GENE ID SPECIES
397282 Sus scrofa
476140 Canis lupus familiaris
100216172 Xenopus (Silurana) tropicalis
100224301 Taeniopygia guttata
100583170 Nomascus leucogenys
92 Homo sapiens
29263 Rattus norvegicus
281598 Bos taurus
396324 Gallus gallus
443304 Ovis aries
399283 Xenopus laevis
553359 Danio rerio
11480 Mus musculus
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