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Activin A Receptor Type II-Like 1 (ACVRL1) ELISA Kits

ACVRL1 encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. Additionally we are shipping ACVRL1 Antibodies (125) and ACVRL1 Proteins (20) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ACVRL1 94 P37023
ACVRL1 25237 P80203
ACVRL1 11482 Q61288
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Top ACVRL1 ELISA Kits at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.049 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$700.00
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Mouse
  96 Tests Log in to see 11 to 13 Days
$785.71
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Rat
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$785.71
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Rabbit
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$785.71
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Guinea Pig
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$801.43
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Pig
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$801.43
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Goat
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$801.43
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Dog
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$801.43
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Cow
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$817.14
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Chicken
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$817.14
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More ELISA Kits for ACVRL1 Interaction Partners

Cow (Bovine) Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. Results show that ALK5 (show TGFBR1 ELISA Kits) and ALK1 play antagonistic roles in TGF-beta (show TGFB1 ELISA Kits)-induced podosome formation in aortic endothelial cells.

  2. ALK1 and ALK5 are both essential for correct regulation of VEGF, and that disruption of either pathway leads to disease.

Zebrafish Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. Control of Notch (show NOTCH1 ELISA Kits) targets in arterial endothelium is context-dependent, with gene-specific and region-specific requirements for Notch (show NOTCH1 ELISA Kits) and Alk1

  2. Blood flow is required not only for alk1 expression but also for Alk1 activity.

  3. Study demonstrate that alk1 expression requires blood flow, and despite normal levels of shear stress, some flow-responsive genes are dysregulated in alk1 mutant arterial endothelial cells.

  4. vbg encodes activin receptor-like kinase 1 (acvrl1), a TGFbeta (show TGFB1 ELISA Kits) type I receptor that is expressed predominantly in the endothelium of the vessels that become dilated in vbg mutants.

Human Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. The preponderance of ACVRL1 mutations was due to founder mutations, specifically, c.830C>A (p.Thr277Lys), which was found in 24 families from the same geographical area of Norway.

  2. Report interaction between ALK1 signaling and connexin40 in the development of arteriovenous malformations.

  3. Data suggest ALK1 and ACVR2A (show ACVR2A ELISA Kits)/ACVR2B (show ACVR2B ELISA Kits), acting as BMP9 (show GDF2 ELISA Kits) co-receptors, rearrange pro-domains of BMP9 (show GDF2 ELISA Kits)--pro-domain dimer complex leading to displacement of pro-domains after receptor binding, release of mature non-dimer BPM9, and activation of signaling.

  4. Short hairpin-mediated downregulation of either ALK5 (show TGFBR1 ELISA Kits) or ALK1 resulted in a strong inhibition of TGFbeta (show TGFB1 ELISA Kits)-induced chondrogenesis.

  5. This work was designed to examine the pathogenicity of 23 nucleotide variations in ACVRL1 gene detected in more than 400 Hereditary Hemorrhagic Telangiectasia syndrome patients.

  6. The ACVRL1 c.314-35A>G polymorphism is associated with organ vascular malformations in hereditary hemorrhagic telangiectasia patients with ENG (show ENG ELISA Kits) mutations, but not in patients with ACVRL1 mutations.

  7. bone morphogenic proteins within the serum of cell culture medium are potent inducers of endothelial Hey1 (show HEY1 ELISA Kits) and Hey2 (show HEY2 ELISA Kits) gene expression within the first few hours after medium change

  8. endoglin (show ENG ELISA Kits) and ALK1 have been identified as potential therapeutic targets for antibody treatment in various cancers.

  9. Mutations in ACVRL1 gene is not associated with pulmonary arterial hypertension.

  10. In chronic subdural hematomas, the expression of ALK-1 was slightly increased in the dura and markedly up-regulated in the outer membrane.

Mouse (Murine) Activin A Receptor Type II-Like 1 (ACVRL1) interaction partners

  1. Conclude that the ALK-1 receptor is involved in the control of arterial pressure. High AP of Alk1(+/-) mice is explained mainly by the sympathetic overactivation, which is probably related to the decreased number of cholinergic neurons.

  2. Report interaction between ALK1 signaling and connexin40 in the development of arteriovenous malformations.

  3. In vascular sprouting, neuropilin-1 (show NRP1 ELISA Kits) suppresses the stalk-cell phenotype by limiting Smad2 (show SMAD2 ELISA Kits)/3 activation through Alk1 and Alk5 (show TGFBR1 ELISA Kits). Notch (show NOTCH1 ELISA Kits) downregulates Nrp1 (show NRP1 ELISA Kits), thus relieving the inhibition of Alk1 and Alk5 (show TGFBR1 ELISA Kits), thereby driving stalk-cell behaviour.

  4. BMP9 (show GDF2 ELISA Kits)/ALK1 augmented vasculogenesis and angiogenesis, and thereby enhanced neovascularization. Thus, we suggest that BMP9 (show GDF2 ELISA Kits)/ALK1 may improve the efficacy of EPC (show TCF21 ELISA Kits)-based therapies for treating ischemic diseases.

  5. BMP-9 (show GDF2 ELISA Kits) induces vascular smooth muscle cell osteogenic differentiation and calcification via ALK1, Smad (show SMAD1 ELISA Kits) and ALP dependent mechanisms.

  6. during development, endothelial Acvrl1 plays an essential role to regulate endothelial cell proliferation and arterial identity during angiogenesis, whilst in adult life endothelial Acvrl1 is required to maintain vascular integrity.

  7. Results show that ALK5 (show TGFBR1 ELISA Kits) and ALK1 play antagonistic roles in TGF-beta (show TGFB1 ELISA Kits)-induced podosome formation in aortic endothelial cells.

  8. ALK1 modulates obstruction-induced renal fibrosis by increased extracellular matrix synthesis in myofibroblasts, but without differences in myofibroblast number.

  9. the mechanisms responsible for the angiogenic imbalance and the response to anti-VEGF (show VEGFA ELISA Kits) therapy differ between Eng (show ENG ELISA Kits) and Alk1 heterozygous mice and raise the need for systemic monitoring of anti-angiogenic therapy effects in HHT patients.

  10. Deletion of Alk1 in endothelial cells in adult mice leads to an increased local endothelial cell proliferation during brain angiogenesis

ACVRL1 Antigen Profile

Antigen Summary

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Gene names and symbols associated with ACVRL1

  • activin A receptor type II-like 1 (ACVRL1) antibody
  • activin A receptor type II-like 1 (acvrl1) antibody
  • activin A receptor type II-like 1 (Acvrl1) antibody
  • activin A receptor, type II-like 1 (Acvrl1) antibody
  • ACVRL1 antibody
  • Acvrlk1 antibody
  • AI115505 antibody
  • AI427544 antibody
  • ALK-1 antibody
  • Alk1 antibody
  • HHT antibody
  • HHT2 antibody
  • hm:zehn1109 antibody
  • ORW2 antibody
  • R-3 antibody
  • R3 antibody
  • SETHKIR antibody
  • SKR3 antibody
  • TSR-I antibody
  • vgb antibody
  • zehn1109 antibody

Protein level used designations for ACVRL1

activin A receptor type II-like 1 , serine/threonine-protein kinase receptor R3 , serine/threonine-protein kinase receptor R3-like , activin receptor-like kinase 1 , vbg , violet beauregarde , TGF-B superfamily receptor type I , activin A receptor, type II-like kinase 1 , Activin receptor like kinase 1 , SKR3 , TSR-I , ALK-1 , activin receptor-like kinase-1

GENE ID SPECIES
451910 Pan troglodytes
534536 Bos taurus
696471 Macaca mulatta
100061313 Equus caballus
100135773 Felis catus
100482358 Ailuropoda melanoleuca
266753 Danio rerio
94 Homo sapiens
25237 Rattus norvegicus
477603 Canis lupus familiaris
100153279 Sus scrofa
100172614 Pongo abelii
11482 Mus musculus
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