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anti-Activin Receptor Type IC (ACVR1C) Antibodies

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Additionally we are shipping Activin Receptor Type IC Proteins (11) and Activin Receptor Type IC Kits (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACVR1C 130399 Q8NER5
ACVR1C 269275 Q8K348
ACVR1C 245921 P70539
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Top anti-Activin Receptor Type IC Antibodies at antibodies-online.com

Showing 10 out of 90 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ACVR1C Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB Mouse Acvr1c Antibody (C-term) (ABIN658527) western blot analysis in mouse heart tissue lysates (35 µg/lane). This demonstrates the Acvr1c antibody detected the Acvr1c protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ACVR1C Antibody (N-term A48) (ABIN391157) in HepG2 and Hela cell line lysate (35 µg/lane). ACVR1C (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. Western blot analysis of anti-ACVR1C Antibody (N-term) in HepG2 and Hela cell line lysate (35ug/lane). ACVR1C (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of ACVR1C in human placenta tissue lysate with AP30016PU-N ACVR1C antibody at (A) 1 and (B) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: HepG2 7.5% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using Activin A Receptor Type IC, antibody at 1:500 dilution. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human stomach labeled with Rabbit Anti ACTRIC/Activin A Receptor Type IC Polyclonal Antibody, Unconjugated (ABIN714596) at 1:200 followed by conjugation to the secondary antibody and DAB staining Lane 1: mouse brain lysates Lane 2: mouse heart lysates probed with Anti ACTRIC/Activin A Receptor Type IC Polyclonal Antibody, Unconjugated (ABIN714596) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 52kD. Observed band size: 52kD. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p) Anti-ACVR1C antibody  ABIN1048286 IHC staining of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-ACVR1C antibody  ABIN1048286 IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF, IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details

ACVR1C Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Activin Receptor Type IC Antibodies

  1. Mouse (Murine) Polyclonal ACVR1C Primary Antibody for WB - ABIN658527 : Andersson, Korach-Andre, Reissmann, Ibáñez, Bertolino: Growth/differentiation factor 3 signals through ALK7 and regulates accumulation of adipose tissue and diet-induced obesity. in Proceedings of the National Academy of Sciences of the United States of America 2008 (PubMed)
    Show all 5 references for ABIN658527

  2. Human Polyclonal ACVR1C Primary Antibody for EIA, IHC (p) - ABIN359225 : Munir, Xu, Wu, Yang, Lala, Peng: Nodal and ALK7 inhibit proliferation and induce apoptosis in human trophoblast cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 references for ABIN359225

  3. Human Polyclonal ACVR1C Primary Antibody for EIA, WB - ABIN499209 : Kogame, Matsuo, Nakatani, Kurisaki, Nishitani, Tsuchida, Sugino: ALK7 is a novel marker for adipocyte differentiation. in The journal of medical investigation : JMI 2006 (PubMed)
    Show all 4 references for ABIN499209

  4. Human Polyclonal ACVR1C Primary Antibody for IHC (p), WB - ABIN391157 : Kim, van Gelder, Kim, Lee, Baik, Chun, Lee, Choi, Kim: Activin receptor-like kinase-7 induces apoptosis through activation of MAPKs in a Smad3-dependent mechanism in hepatoma cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for ABIN391157

More Antibodies against Activin Receptor Type IC Interaction Partners

Human Activin Receptor Type IC (ACVR1C) interaction partners

  1. Loss of ALK7 expression are associated with invasion, metastasis of the pancreatic ductal adenocarcinoma.

  2. Alk7 is expressed in male germ cells and Sertoli cells.

  3. ACVR (show ACRV1 Antibodies) 1C is a tumor suppressor, and lowered ACVR (show ACRV1 Antibodies) 1C expression is an important marker for the metastasis, invasion, and prognosis of gallbladder cancer.

  4. Our findings suggested that the ALK7 gene polymorphism rs13010956 was significantly associated with metabolic syndrome risk in females and may be involved in cardiovascular remodeling in metabolic syndrome patients.

  5. reduction or lack of ALK7 expression may account for the loss of its ligand sensitivity of breast cancer cells, thereby leading to breast tumor progression.

  6. These findings suggest that the Nodal/ALK7 pathway plays important roles in human placentation and that its abnormal signaling may contribute to the development of preeclampsia.

  7. ALK7 and its isoforms are expressed in human placentae of different stages of pregnancy and that their expression is developmentally regulated

  8. ALK7 induces apoptosis through activation of the traditional TGF-beta (show TGFB1 Antibodies) pathway components

  9. the Nodal-ALK7 pathway inhibits cell proliferation by inducing G(1) cell cycle arrest

  10. AB and activin B and is responsible for ac (show Actbeta Antibodies)tivin-mediated se (show Actbeta Antibodies)cretion of insulin from pancrea (show Actbeta Antibodies)tic beta cell line, MIN6.

Mouse (Murine) Activin Receptor Type IC (ACVR1C) interaction partners

  1. ALK7 protects against pathological cardiac hypertrophy in mice.

  2. These findings suggest that endogenous expression of ALK7 is necessary to maintain repolarizing K+ currents in ventricular cardiomyocytes, and finally prevent action potential prolongation and ventricular arrhythmia.

  3. ALK7 signaling contributes to diet-induced catecholamine resistance in adipose tissue; ALK7 inhibitors may have therapeutic value in human obesity.

  4. Signaling through the TGF beta (show TGFB1 Antibodies)-activin (show Actbeta Antibodies) receptors ALK4 (show ACVR1B Antibodies)/5/7 regulates testis formation and male germ cell development.

  5. Alk7 is involved in modulation of adipose tissue metabolism in response to beta3-adrenergic receptor (show ADRB3 Antibodies) activation.

  6. Data indicate that activin receptor ALK7-knockout females showed delayed onset of puberty and abnormal estrous cyclicity.

  7. Activin receptor-like kinase 7 suppresses lipolysis to accumulate fat in obesity through downregulation of peroxisome proliferator-activated receptor gamma (show PPARG Antibodies) and C/EBPalpha (show CEBPA Antibodies).

  8. Knockdown or pharmacological inhibition of the Nodal/Activin receptor Alk4 (show ACVR1B Antibodies)/7 in cancer stem cells virtually abrogated their self-renewal capacity and in vivo tumorigenicity

  9. ALK7 is the signaling receptor for activin (show Actbeta Antibodies) AB and activin B (show Actbeta Antibodies) and is responsible for activin (show Actbeta Antibodies)-mediated secretion of insulin (show INS Antibodies) from pancreatic beta cell line, MIN6.

  10. ALK7 is not an essential mediator of Nodal signaling during mesendoderm formation and left-right patterning in the mouse but may instead mediate other activities of Nodal and related ligands in the development or function of particular tissues and organs

Activin Receptor Type IC (ACVR1C) Antigen Profile

Protein Summary

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001

Gene names and symbols associated with ACVR1C

  • activin A receptor, type IC (ACVR1C) antibody
  • activin A receptor, type IC (Acvr1c) antibody
  • ACVRLK7 antibody
  • Alk-7 antibody
  • Alk7 antibody
  • C230097P10 antibody
  • habrec1 antibody

Protein level used designations for ACVR1C

ACTR-IC , ALK-7 , activin receptor type IC , activin receptor type-1C , activin receptor-like kinase 7 , TGF-beta type 1 receptor , activin A receptor, type IC

GENE ID SPECIES
130399 Homo sapiens
269275 Mus musculus
245921 Rattus norvegicus
488361 Canis lupus familiaris
100156756 Sus scrofa
536380 Bos taurus
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