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anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Antibodies

ACADM encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. Additionally we are shipping Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Proteins (15) and Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ACADM 34 P11310
ACADM 24158 P08503
ACADM 11364 P45952
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Top anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Antibodies at antibodies-online.com

Showing 10 out of 94 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ACADM Antibody Titration: 0.2-1 ug/mlPositive Contro... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ACADM Antibody Titration: 5.0ug/mlPositive Control: ... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Goat Un-conjugated IHC, ELISA, WB ABIN184850 staining (0.05µg/ml) of Human Heart lysate (RIPA buffer, 35... 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of ACADM Antibody (Center) (ABIN390808) in mouse... Formalin-fixed and paraffin-embedded human colon carcinoma reacted wit... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$283.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample A: 30μg of A431 whole cell lysate , 7.5% SDS PAGE anti... ICC/IF Image Immunofluorescence analysis of methanol-fixed A431, using... 100 μL Log in to see 2 to 3 Days
$358.60
Details

ACADM Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
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Rat (Rattus) , , , ,
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Mouse (Murine) , , , ,
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Top referenced anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Antibodies

  1. Human Polyclonal ACADM Primary Antibody for FACS, IF - ABIN390808 : Ferreira, Orlandi, Oliveira, Malta, Caxito, Gomes, Valadares, Godard: A985G mutation incidence in the medium-chain acyl-CoA dehydrogenase (MCAD) gene in Brazil. in Genetics and molecular research : GMR 2009 (PubMed)

  2. Human Polyclonal ACADM Primary Antibody for ELISA, WB - ABIN559743 : Rennison, McElfresh, Okere, Patel, Foster, Patel, Stoll, Minkler, Fujioka, Hoit, Young, Hoppel, Chandler: Enhanced acyl-CoA dehydrogenase activity is associated with improved mitochondrial and contractile function in heart failure. in Cardiovascular research 2008 (PubMed)

  3. Human Polyclonal ACADM Primary Antibody for IHC, ELISA - ABIN184850 : Matsubara, Kraus, Yang-Feng, Francke, Rosenberg, Tanaka: Molecular cloning of cDNAs encoding rat and human medium-chain acyl-CoA dehydrogenase and assignment of the gene to human chromosome 1. in Proceedings of the National Academy of Sciences of the United States of America 1986 (PubMed)

  4. Cow (Bovine) Polyclonal ACADM Primary Antibody for WB - ABIN2777594 : Parker: Binding of the human \electron transferring flavoprotein\" (ETF) to the medium chain acyl-CoA dehydrogenase (MCAD) involves an arginine and histidine residue." in Journal of enzyme inhibition and medicinal chemistry 2003 (PubMed)

  5. Human Polyclonal ACADM Primary Antibody for IHC (p), WB - ABIN374273 : Powelka, Seth, Virbasius, Kiskinis, Nicoloro, Guilherme, Tang, Straubhaar, Cherniack, Parker, Czech: Suppression of oxidative metabolism and mitochondrial biogenesis by the transcriptional corepressor RIP140 in mouse adipocytes. in The Journal of clinical investigation 2006 (PubMed)

  6. Cow (Bovine) Polyclonal ACADM Primary Antibody for WB - ABIN2777593 : Nichols, Saavedra-Matiz, Pass, Caggana: Novel mutations causing medium chain acyl-CoA dehydrogenase deficiency: under-representation of the common c.985 A > G mutation in the New York state population. in American journal of medical genetics. Part A 2008 (PubMed)

More Antibodies against Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Interaction Partners

Human Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. our study demonstrates that not all mutations identified in children with abnormal NBS (show NBN Antibodies) profiles suggestive of MCAD deficiency result in a total loss in MCAD activity and function

  2. mutations in the ACADM gene lower the temperature threshold at which medium-chain acyl-CoA dehydrogenase deficiency loss-of-function occurs.

  3. Segregation studies in the Gypsy families showed that 93/123 relatives were carriers of the acyl-coenzyme A (show SOAT2 Antibodies) dehydrogenase G985 allele, suggesting its high prevalence in this ethnic group.

  4. Identify an ACADM founder mutation for MCADD in Saudi Arabian population.

  5. This supports that c.1161A>G is a functional SNP, which leads to higher MCAD expression, perhaps due to improved splicing. This study is a proof of principle that synonymous SNPs are not neutral.

  6. medium chain acyl-CoA dehydrogenase involve in the metabolism of phenylbutyrate.

  7. Subjects with variant ACADM genotypes and residual MCAD enzyme activities <10% should be considered to have the same risks as patients with classical ACADM genotypes

  8. The octanoyl-CoA oxidation rate, therefore, allows a risk assessment at birth and the identification of new ACADM genotypes associated with asymptomatic disease variants.

  9. A novel variant in the Medium-Chain Acyl-CoA Dehydrogenase (MCAD) gene was identified in a Greek cohort of neonates with suspected MCAD deficiency.

  10. The mutation in Medium-chain acyl-CoA dehydrogenase deficiency is the first report of the c.461T>G mutation in the acyl-CoA dehydrogenase gene.

Pig (Porcine) Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. Investigation of ACADM in relation to fat deposition traits.

  2. Investigation of structure of enzyme (from kidney) complexed with FAD analogs (e.g., 8-NH2-FAD) and acyl-CoA (e.g., octanoyl-CoA).

Mouse (Murine) Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. the transcriptional regulatory circuits involved in the control of MCAD gene expression under hypoxic conditions are modulated by upstream factors that are sensitive to the levels of oxygen

  2. MCAD is reduced in liver, heart & kidney in lipopolysaccharide-induced acute phase response; binding liver nuclear extracts to ERRalpha (show ESRRA Antibodies) response element found in promoter region of MCAD was decreased during APR (show PMAIP1 Antibodies), suggesting less transcription of MCAD

  3. The MCAD-/- mice developed an organic aciduria and fatty liver, and showed profound cold intolerance at 4 degrees C with prior fasting.

  4. MCAD deficiency in mice leads to specific changes in hepatic carbohydrate management on exposure to metabolic stress.

  5. A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes (MCAD/citrate synthase (show CS Antibodies)) without affecting development of heart failure with pressure overload.

Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Antigen Profile

Protein Summary

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ACADM

  • acyl-CoA dehydrogenase (acd) antibody
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (ACADM) antibody
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (acadm) antibody
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (Acadm) antibody
  • acyl-Coenzyme A dehydrogenase, medium chain (Acadm) antibody
  • ACAD1 antibody
  • acaDM antibody
  • AU018656 antibody
  • MCAD antibody
  • MCADH antibody

Protein level used designations for ACADM

acyl-CoA dehydrogenase, C-4 to C-12 straight chain , medium-chain acyl-CoA dehydrogenase , acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain , medium-chain specific acyl-CoA dehydrogenase, mitochondrial-like , medium-chain specific acyl-CoA dehydrogenase, mitochondrial , C-4 to C-12 straight chain acyl-coenzyme A dehydrogenase , MCAD , acyl-coenzyme A dehydrogenase, C-4 to C-12 straight chain , Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain , Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain , acyl-Coenzyme A dehydrogenase, medium chain , acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, nuclear gene encoding mitochondrial protein

GENE ID SPECIES
8792410 Azospirillum sp. B510
8793572 Azospirillum sp. B510
100347504 Oryctolagus cuniculus
446467 Xenopus laevis
705168 Macaca mulatta
100391471 Callithrix jacchus
100600902 Nomascus leucogenys
34 Homo sapiens
505968 Bos taurus
24158 Rattus norvegicus
397104 Sus scrofa
490207 Canis lupus familiaris
469356 Pan troglodytes
11364 Mus musculus
Selected quality suppliers for anti-Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Antibodies
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