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Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) ELISA Kits

ACADM encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. Additionally we are shipping Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Antibodies (98) and Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Proteins (15) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ACADM 34 P11310
ACADM 24158 P08503
ACADM 11364 P45952
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Top Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain ELISA Kits at antibodies-online.com

Showing 5 out of 5 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Rat 0.78-50 ng/mL 96 Tests Log in to see 11 to 13 Days
$1,029.60
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Human
96 Tests Log in to see 11 to 13 Days
$743.60
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Mouse
96 Tests Log in to see 11 to 13 Days
$1,029.60
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Pig
96 Tests Log in to see 11 to 13 Days
$1,029.60
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Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
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More ELISA Kits for Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain Interaction Partners

Human Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. our study demonstrates that not all mutations identified in children with abnormal NBS (show NBN ELISA Kits) profiles suggestive of MCAD deficiency result in a total loss in MCAD activity and function

  2. mutations in the ACADM gene lower the temperature threshold at which medium-chain acyl-CoA dehydrogenase deficiency loss-of-function occurs.

  3. Segregation studies in the Gypsy families showed that 93/123 relatives were carriers of the acyl-coenzyme A (show SOAT2 ELISA Kits) dehydrogenase G985 allele, suggesting its high prevalence in this ethnic group.

  4. Identify an ACADM founder mutation for MCADD in Saudi Arabian population.

  5. This supports that c.1161A>G is a functional SNP, which leads to higher MCAD expression, perhaps due to improved splicing. This study is a proof of principle that synonymous SNPs are not neutral.

  6. medium chain acyl-CoA dehydrogenase involve in the metabolism of phenylbutyrate.

  7. Subjects with variant ACADM genotypes and residual MCAD enzyme activities <10% should be considered to have the same risks as patients with classical ACADM genotypes

  8. The octanoyl-CoA oxidation rate, therefore, allows a risk assessment at birth and the identification of new ACADM genotypes associated with asymptomatic disease variants.

  9. A novel variant in the Medium-Chain Acyl-CoA Dehydrogenase (MCAD) gene was identified in a Greek cohort of neonates with suspected MCAD deficiency.

  10. The mutation in Medium-chain acyl-CoA dehydrogenase deficiency is the first report of the c.461T>G mutation in the acyl-CoA dehydrogenase gene.

Pig (Porcine) Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. Investigation of ACADM in relation to fat deposition traits.

  2. Investigation of structure of enzyme (from kidney) complexed with FAD analogs (e.g., 8-NH2-FAD) and acyl-CoA (e.g., octanoyl-CoA).

Mouse (Murine) Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) interaction partners

  1. the transcriptional regulatory circuits involved in the control of MCAD gene expression under hypoxic conditions are modulated by upstream factors that are sensitive to the levels of oxygen

  2. MCAD is reduced in liver, heart & kidney in lipopolysaccharide-induced acute phase response; binding liver nuclear extracts to ERRalpha (show ESRRA ELISA Kits) response element found in promoter region of MCAD was decreased during APR (show PMAIP1 ELISA Kits), suggesting less transcription of MCAD

  3. The MCAD-/- mice developed an organic aciduria and fatty liver, and showed profound cold intolerance at 4 degrees C with prior fasting.

  4. MCAD deficiency in mice leads to specific changes in hepatic carbohydrate management on exposure to metabolic stress.

  5. A high-fat diet increases adiposity but maintains mitochondrial oxidative enzymes (MCAD/citrate synthase (show CS ELISA Kits)) without affecting development of heart failure with pressure overload.

Acyl-CoA Dehydrogenase, C-4 To C-12 Straight Chain (ACADM) Antigen Profile

Antigen Summary

This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ACADM

  • acyl-CoA dehydrogenase (acd) antibody
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (ACADM) antibody
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (acadm) antibody
  • acyl-CoA dehydrogenase, C-4 to C-12 straight chain (Acadm) antibody
  • acyl-Coenzyme A dehydrogenase, medium chain (Acadm) antibody
  • ACAD1 antibody
  • acaDM antibody
  • AU018656 antibody
  • MCAD antibody
  • MCADH antibody

Protein level used designations for ACADM

acyl-CoA dehydrogenase, C-4 to C-12 straight chain , medium-chain acyl-CoA dehydrogenase , acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain , medium-chain specific acyl-CoA dehydrogenase, mitochondrial-like , medium-chain specific acyl-CoA dehydrogenase, mitochondrial , C-4 to C-12 straight chain acyl-coenzyme A dehydrogenase , MCAD , acyl-coenzyme A dehydrogenase, C-4 to C-12 straight chain , Acyl-Coenzyme A dehydrogenase C-4 to C-12 straight-chain , Acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight-chain , acyl-Coenzyme A dehydrogenase, medium chain , acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain, nuclear gene encoding mitochondrial protein

GENE ID SPECIES
8792410 Azospirillum sp. B510
8793572 Azospirillum sp. B510
100347504 Oryctolagus cuniculus
446467 Xenopus laevis
705168 Macaca mulatta
100391471 Callithrix jacchus
100600902 Nomascus leucogenys
34 Homo sapiens
505968 Bos taurus
24158 Rattus norvegicus
397104 Sus scrofa
490207 Canis lupus familiaris
469356 Pan troglodytes
11364 Mus musculus
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